CN101316832A - δ-9-四氢大麻酚的生成方法 - Google Patents

δ-9-四氢大麻酚的生成方法 Download PDF

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Publication number
CN101316832A
CN101316832A CNA2006800443431A CN200680044343A CN101316832A CN 101316832 A CN101316832 A CN 101316832A CN A2006800443431 A CNA2006800443431 A CN A2006800443431A CN 200680044343 A CN200680044343 A CN 200680044343A CN 101316832 A CN101316832 A CN 101316832A
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CN
China
Prior art keywords
sulphonate
compound
alkyl
replacement
aryl
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Pending
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CNA2006800443431A
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English (en)
Chinese (zh)
Inventor
D·C·伯迪克
S·J·科利尔
F·乔斯
B·比奥拉托
B·J·保罗
H·梅克勒
M·A·海勒
A·J·哈伯肖
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Curia Global Inc
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AMR Technology Inc
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Publication of CN101316832A publication Critical patent/CN101316832A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/11—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
    • C07C37/16—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms by condensation involving hydroxy groups of phenols or alcohols or the ether or mineral ester group derived therefrom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
CNA2006800443431A 2005-09-29 2006-09-28 δ-9-四氢大麻酚的生成方法 Pending CN101316832A (zh)

Applications Claiming Priority (2)

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US72203105P 2005-09-29 2005-09-29
US60/722,031 2005-09-29

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CN101316832A true CN101316832A (zh) 2008-12-03

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CNA2006800443431A Pending CN101316832A (zh) 2005-09-29 2006-09-28 δ-9-四氢大麻酚的生成方法

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EP (3) EP2578577A1 (US07674922-20100309-C00031.png)
JP (1) JP2009510078A (US07674922-20100309-C00031.png)
KR (1) KR20080063800A (US07674922-20100309-C00031.png)
CN (2) CN102766128A (US07674922-20100309-C00031.png)
AU (1) AU2006297300B2 (US07674922-20100309-C00031.png)
CA (1) CA2623723A1 (US07674922-20100309-C00031.png)
IL (1) IL190388A0 (US07674922-20100309-C00031.png)
NZ (3) NZ601567A (US07674922-20100309-C00031.png)
WO (1) WO2007041167A2 (US07674922-20100309-C00031.png)
ZA (1) ZA200802767B (US07674922-20100309-C00031.png)

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CN106632214A (zh) * 2016-12-28 2017-05-10 西北大学 一种大麻酚类化合物的合成方法
CN109153661A (zh) * 2016-05-13 2019-01-04 西姆莱斯有限公司 用于纯化大麻素化合物的方法
CN111372907A (zh) * 2017-09-01 2020-07-03 普优峰全球股份有限公司 合成大麻二酚组合物和用于制备其的方法
CN111943813A (zh) * 2019-05-17 2020-11-17 上海特化医药科技有限公司 大麻二酚类化合物的制备方法
CN112094257A (zh) * 2020-08-19 2020-12-18 公安部禁毒情报技术中心 一种△-9四氢大麻酚的制备方法
CN113087743A (zh) * 2020-01-08 2021-07-09 成都百裕制药股份有限公司 四氢大麻酚衍生物及其制备方法和在医药上的应用
CN113896616A (zh) * 2020-07-06 2022-01-07 复旦大学 一种大麻二酚的制备方法
CN114269717A (zh) * 2019-05-23 2022-04-01 凯尔化学科技公司 催化大麻素方法和前体
CN114644547A (zh) * 2020-12-21 2022-06-21 云南汉盟制药有限公司 一种大麻二酚和/或次大麻二酚的制备方法
CN115504864A (zh) * 2021-06-07 2022-12-23 南通新世元生物科技有限公司 从工业大麻中获取高纯度大麻二酚的方法

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