CN101273034B - 抑制由vla-4介导的白细胞粘附的嘧啶基酰胺化合物 - Google Patents

抑制由vla-4介导的白细胞粘附的嘧啶基酰胺化合物 Download PDF

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CN101273034B
CN101273034B CN2006800356541A CN200680035654A CN101273034B CN 101273034 B CN101273034 B CN 101273034B CN 2006800356541 A CN2006800356541 A CN 2006800356541A CN 200680035654 A CN200680035654 A CN 200680035654A CN 101273034 B CN101273034 B CN 101273034B
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nitrogen
ring
heterocycle
alkyl
ethyl
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CN101273034A (zh
Inventor
克里斯托夫·迈克尔·塞姆科
许英姿
弗兰克·斯塔潘贝克
珍妮弗·莉·史密斯
卡桑德拉·伊内兹·罗西特
朱里·Y·福田
安德烈·W·康拉迪
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Wyeth LLC
Elan Pharmaceuticals LLC
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Elan Pharmaceuticals LLC
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CN2006800356541A 2005-09-29 2006-09-28 抑制由vla-4介导的白细胞粘附的嘧啶基酰胺化合物 Expired - Fee Related CN101273034B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72235805P 2005-09-29 2005-09-29
US60/722,358 2005-09-29
PCT/US2006/038009 WO2007041270A1 (en) 2005-09-29 2006-09-28 Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by vla-4

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CN101273034A CN101273034A (zh) 2008-09-24
CN101273034B true CN101273034B (zh) 2011-07-27

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US (2) US7511052B2 (enExample)
EP (1) EP1940826B1 (enExample)
JP (1) JP5101512B2 (enExample)
KR (1) KR20080059268A (enExample)
CN (1) CN101273034B (enExample)
AT (1) ATE493405T1 (enExample)
AU (1) AU2006297220B8 (enExample)
BR (1) BRPI0616687A2 (enExample)
CA (1) CA2624450C (enExample)
DE (1) DE602006019296D1 (enExample)
DK (1) DK1940826T3 (enExample)
EA (1) EA015388B1 (enExample)
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NO (1) NO20082002L (enExample)
NZ (1) NZ567270A (enExample)
WO (1) WO2007041270A1 (enExample)
ZA (2) ZA200803280B (enExample)

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WO2007100763A2 (en) * 2006-02-28 2007-09-07 Elan Pharmaceuticals, Inc. Methods of treating inflammatory and autoimmune diseases with alpha-4 inhibitory compounds
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US20240301512A1 (en) 2021-01-29 2024-09-12 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of assessing the risk of developing progressive multifocal leukoencephalopathy in patients treated with vla-4 antagonists
CN118871130A (zh) * 2022-03-11 2024-10-29 国立大学法人大阪大学 包含vla-4阻断物质的用于预防或治疗心肌炎的组合物

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