CN101171237B - 用于制备任选2-取代的1，6-二氢-6-氧代-4-嘧啶羧酸的方法 - Google Patents

用于制备任选2-取代的1，6-二氢-6-氧代-4-嘧啶羧酸的方法 Download PDF

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CN101171237B
CN101171237B CN200680015454XA CN200680015454A CN101171237B CN 101171237 B CN101171237 B CN 101171237B CN 200680015454X A CN200680015454X A CN 200680015454XA CN 200680015454 A CN200680015454 A CN 200680015454A CN 101171237 B CN101171237 B CN 101171237B
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formula
compound
replaces
acid
cyclopropyl
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CN101171237A (zh
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R·夏皮罗
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Kedihua Agricultural Technology Co ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN200680015454XA 2005-05-06 2006-04-28 用于制备任选2-取代的1，6-二氢-6-氧代-4-嘧啶羧酸的方法 Active CN101171237B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67826405P 2005-05-06 2005-05-06
US60/678,264 2005-05-06
PCT/US2006/016340 WO2006121648A2 (en) 2005-05-06 2006-04-28 Method for preparation of optionally 2-substituted 1,6-dihydro-6-oxo-4-pyrimidinecarboxylic acids

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CN2011100456237A Division CN102153516B (zh) 2005-05-06 2006-04-28 用于制备嘧啶羧酸化合物的中间体

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CN101171237A CN101171237A (zh) 2008-04-30
CN101171237B true CN101171237B (zh) 2011-04-20

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CN2011100456237A Active CN102153516B (zh) 2005-05-06 2006-04-28 用于制备嘧啶羧酸化合物的中间体
CN200680015454XA Active CN101171237B (zh) 2005-05-06 2006-04-28 用于制备任选2-取代的1，6-二氢-6-氧代-4-嘧啶羧酸的方法

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US (2) US8198442B2 (OSRAM)
EP (1) EP1877384B1 (OSRAM)
JP (1) JP5161764B2 (OSRAM)
KR (1) KR101379967B1 (OSRAM)
CN (2) CN102153516B (OSRAM)
AT (1) ATE506352T1 (OSRAM)
AU (1) AU2006246374B2 (OSRAM)
BR (1) BRPI0612475B8 (OSRAM)
CA (1) CA2607934C (OSRAM)
DE (1) DE602006021411D1 (OSRAM)
DK (1) DK1877384T3 (OSRAM)
EG (1) EG25480A (OSRAM)
ES (1) ES2362005T3 (OSRAM)
GE (1) GEP20105099B (OSRAM)
IL (2) IL185885A (OSRAM)
MA (1) MA29464B1 (OSRAM)
ME (1) ME00498B (OSRAM)
MX (1) MX2007013424A (OSRAM)
NZ (1) NZ561399A (OSRAM)
PL (1) PL1877384T3 (OSRAM)
RS (2) RS20070434A (OSRAM)
TN (1) TNSN07403A1 (OSRAM)
UA (1) UA92171C2 (OSRAM)
WO (1) WO2006121648A2 (OSRAM)
ZA (1) ZA200707975B (OSRAM)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006247581B2 (en) * 2005-05-16 2011-10-20 E. I. Du Pont De Nemours And Company Method for preparing substituted pyrimidines
EP1931619B1 (en) * 2005-09-29 2015-06-24 DSM Sinochem Pharmaceuticals Netherlands B.V. Methanesulphonic acid salt of dihydrophenylglycine methyl ester or of phenylglycine methyl ester
ES2401348T3 (es) * 2007-08-13 2013-04-18 Dow Agrosciences, Llc 2-(Fenil 2-fluoro-substituido)-6-amino-5-cloro-4-pirimidinacarboxilatos y su uso como herbicidas
EP2327694B1 (en) 2007-10-02 2013-07-24 Dow AgroSciences LLC Substituted 4-amino-picolinic acids and their use as herbicides
RU2454407C1 (ru) * 2008-04-18 2012-06-27 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи 2-(замещенный фенил)-6-гидрокси или алкокси-5-замещенные-4-пиримидинкарбоксилаты и их применение в качестве гербицидов
TWI596088B (zh) * 2011-01-25 2017-08-21 陶氏農業科學公司 ４－胺基－６－（經取代的苯基）吡啶甲酸酯及６－胺基－２－（經取代的苯基）－４－嘧啶羧酸酯之芳烷酯以及其等作為除草劑之用途
BR112014001882B1 (pt) * 2011-07-27 2019-05-07 Bayer Intellectual Property Gmbh Composições herbicidas, uso de ácidos picolínicos e ácidos pirimidina-4-carboxílicos substituídos, e método para controlar plantas indesejadas
US9113629B2 (en) * 2013-03-15 2015-08-25 Dow Agrosciences Llc 4-amino-6-(4-substituted-phenyl)-picolinates and 6-amino-2-(4-substituted-phenyl)-pyrimidine-4-carboxylates and their use as herbicides
US9637505B2 (en) 2013-03-15 2017-05-02 Dow Agrosciences Llc 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic)pyrimidine-4-carboxylates and their use as herbicides
KR102305436B1 (ko) * 2013-03-15 2021-09-27 코르테바 애그리사이언스 엘엘씨 4-아미노-6-(헤테로시클릭)피콜리네이트 및 6-아미노-2-(헤테로시클릭)피리미딘-4-카르복실레이트 및 제초제로서의 그의 용도
TWI689252B (zh) 2014-09-15 2020-04-01 美商陶氏農業科學公司 源自於施用吡啶羧酸除草劑與乙醯乳酸合成酶（ａｌｓ）抑制劑的協同性雜草控制
TWI685302B (zh) 2014-09-15 2020-02-21 美商陶氏農業科學公司 包含吡啶羧酸除草劑之安全的除草組成物
AR101858A1 (es) 2014-09-15 2017-01-18 Dow Agrosciences Llc Composiciones herbicidas protegidas que comprenden un herbicida de ácido piridincarboxílico
TWI689251B (zh) 2014-09-15 2020-04-01 美商陶氏農業科學公司 源自於施用吡啶羧酸除草劑與合成生長素除草劑及/或生長素轉運抑制劑的協同性雜草控制
US10455836B2 (en) 2014-09-15 2019-10-29 Dow Agrosciences Llc Synergistic weed control from applications of pyridine carboxylic acid herbicides and photosystem II inhibitors

Citations (1)

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US4666915A (en) * 1983-11-05 1987-05-19 Morishita Pharmaceutical Co. Ltd. 2-anilino-1,6-dihydro-6-oxo-5-pyrimidine-carboxylic acid derivatives, process for the preparation thereof, and antiallergic agent containing the same

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CA207185A (en) 1921-01-04 C. Wagner Virgil Warming plate
JPH0331267A (ja) 1989-06-28 1991-02-12 Morishita Pharmaceut Co Ltd ２―アニリノ―１，６―ジヒドロ―６―オキソ―４―ピリミジンカルボン酸誘導体
JPH0341071A (ja) 1989-07-06 1991-02-21 Morishita Pharmaceut Co Ltd １，６―ジヒドロ―６―オキソ―２―フェノキシアルキルチオ―５―ピリミジンカルボン酸類
DE3935277A1 (de) 1989-10-24 1991-05-02 Hoechst Ag Sulfonierte heterocyclische carboxamide, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als herbizide oder wachstumsregulatoren
US5637618A (en) 1990-06-01 1997-06-10 Bioresearch, Inc. Specific eatable taste modifiers
DE4029654A1 (de) 1990-09-19 1992-04-02 Hoechst Ag 2-phenyl-pyrimidine, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide
DE4131924A1 (de) 1991-09-25 1993-07-08 Hoechst Ag Substituierte 4-alkoxypyrimidine, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
DE4408404A1 (de) 1994-03-12 1995-09-14 Huels Chemische Werke Ag Verfahren zur Herstellung von Chlorpyrimidinen
CA2321153A1 (en) 1998-02-17 1999-08-19 Timothy D. Cushing Anti-viral pyrimidine derivatives
SK285728B6 (sk) 1999-04-15 2007-07-06 Basf Aktiengesellschaft Spôsob prípravy substituovaných pyrimidínov
US6281358B1 (en) 1999-04-15 2001-08-28 American Cyanamid Company Process for the preparation of substituted pyrimidines
US20030130264A1 (en) 2001-02-16 2003-07-10 Tularik Inc. Methods of using pyrimidine-based antiviral agents
ATE440825T1 (de) 2003-06-06 2009-09-15 Vertex Pharma Pyrimidin-derivate zur verwendung als modulatoren von atp-bindende kassette transportern
TWI355894B (en) 2003-12-19 2012-01-11 Du Pont Herbicidal pyrimidines
JPWO2006083012A1 (ja) 2005-02-02 2008-06-26 味の素株式会社 ピリミジン化合物の製造方法
DE102005027150A1 (de) 2005-03-12 2006-09-28 Bayer Healthcare Ag Pyrimidincarbonsäure-Derivate und ihre Verwendung
AU2006247581B2 (en) 2005-05-16 2011-10-20 E. I. Du Pont De Nemours And Company Method for preparing substituted pyrimidines

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Publication number Priority date Publication date Assignee Title
US4666915A (en) * 1983-11-05 1987-05-19 Morishita Pharmaceutical Co. Ltd. 2-anilino-1,6-dihydro-6-oxo-5-pyrimidine-carboxylic acid derivatives, process for the preparation thereof, and antiallergic agent containing the same

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Title
Daves G. D. et al.Pyrimidines. Ⅱ. Orotic Acid Analogs.《J. Org. Chem.》.1961,第26卷(第8期),2755-2763.
Daves G. D. et al.Pyrimidines. Ⅱ. Orotic Acid Analogs.《J. Org. Chem.》.1961,第26卷(第8期),2755-2763. *
Gershon H..Pyrimidines. Ⅱ. Chlorinated Pyrimidines Derived from OroticAcid.《J. Org. Chem.》.1962,第27卷(第10期),3507-3510. *
徐进宜等.1-取代2-烷基-4-氯-1 6-二氢-6-甲基-5-嘧啶甲酸乙酯类化合物的合成及其降压活性.《中国药科大学学报》.1999
徐进宜等.1-取代2-烷基-4-氯-1, 6-二氢-6-甲基-5-嘧啶甲酸乙酯类化合物的合成及其降压活性.《中国药科大学学报》.1999,第30卷(第6期),406-410. *

Also Published As

Publication number Publication date
CA2607934A1 (en) 2006-11-16
CN102153516A (zh) 2011-08-17
MX2007013424A (es) 2008-01-16
BRPI0612475B8 (pt) 2022-12-06
RS20070434A (sr) 2009-01-22
ZA200707975B (en) 2008-11-26
WO2006121648A2 (en) 2006-11-16
AU2006246374A1 (en) 2006-11-16
AU2006246374B2 (en) 2012-03-29
DK1877384T3 (da) 2011-08-15
EP1877384B1 (en) 2011-04-20
JP2008540414A (ja) 2008-11-20
DE602006021411D1 (de) 2011-06-01
CN102153516B (zh) 2013-02-06
BRPI0612475A2 (pt) 2010-11-23
IL185885A0 (en) 2008-01-06
BRPI0612475B1 (pt) 2020-03-10
KR101379967B1 (ko) 2014-04-01
PL1877384T3 (pl) 2011-09-30
GEP20105099B (en) 2010-10-25
CN101171237A (zh) 2008-04-30
ATE506352T1 (de) 2011-05-15
WO2006121648A3 (en) 2006-12-28
RS51804B (sr) 2011-12-31
US8198442B2 (en) 2012-06-12
UA92171C2 (ru) 2010-10-11
EG25480A (en) 2012-01-15
JP5161764B2 (ja) 2013-03-13
IL222041A (en) 2016-10-31
EP1877384A2 (en) 2008-01-16
KR20080006576A (ko) 2008-01-16
US20090043098A1 (en) 2009-02-12
TNSN07403A1 (en) 2009-03-17
NZ561399A (en) 2009-11-27
US20120232271A1 (en) 2012-09-13
ME00498B (me) 2011-10-10
MA29464B1 (fr) 2008-05-02
IL185885A (en) 2012-10-31
ES2362005T3 (es) 2011-06-27
CA2607934C (en) 2013-10-01

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Effective date of registration: 20220908

Address after: Indiana, USA

Patentee after: Kedihua Agricultural Technology Co.,Ltd.

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Patentee before: DuPont