CN100531886C - 形成微米和亚微米颗粒的装置及其方法 - Google Patents

形成微米和亚微米颗粒的装置及其方法 Download PDF

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Publication number
CN100531886C
CN100531886C CNB028055683A CN02805568A CN100531886C CN 100531886 C CN100531886 C CN 100531886C CN B028055683 A CNB028055683 A CN B028055683A CN 02805568 A CN02805568 A CN 02805568A CN 100531886 C CN100531886 C CN 100531886C
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China
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supercritical fluid
solution
nozzle
solvent
particle formation
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English (en)
Chinese (zh)
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CN1494455A (zh
Inventor
乔瓦尼·德尔里
马蒂奥·帕特里格纳诺
加布里埃尔·迪贾科莫
西泽尔·迪帕尔马
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Dompe SpA
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Dompe SpA
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/08—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Disintegrating Or Milling (AREA)
  • Glanulating (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Luminescent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
CNB028055683A 2001-02-26 2002-02-26 形成微米和亚微米颗粒的装置及其方法 Expired - Fee Related CN100531886C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01104705.7 2001-02-26
EP01104705 2001-02-26

Publications (2)

Publication Number Publication Date
CN1494455A CN1494455A (zh) 2004-05-05
CN100531886C true CN100531886C (zh) 2009-08-26

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ID=8176607

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CNB028055683A Expired - Fee Related CN100531886C (zh) 2001-02-26 2002-02-26 形成微米和亚微米颗粒的装置及其方法

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Country Link
US (2) US7175886B2 (enExample)
EP (1) EP1363726B1 (enExample)
JP (1) JP4405153B2 (enExample)
KR (1) KR100858956B1 (enExample)
CN (1) CN100531886C (enExample)
AT (1) ATE274995T1 (enExample)
AU (1) AU2002236021B2 (enExample)
BR (1) BR0207570B1 (enExample)
CA (1) CA2438275C (enExample)
CZ (1) CZ301857B6 (enExample)
DE (1) DE60201127T2 (enExample)
DK (1) DK1363726T3 (enExample)
EE (1) EE05100B1 (enExample)
ES (1) ES2223034T3 (enExample)
HU (1) HU228083B1 (enExample)
IL (2) IL157346A0 (enExample)
MX (1) MXPA03007541A (enExample)
NO (1) NO331676B1 (enExample)
NZ (1) NZ528082A (enExample)
PL (1) PL205820B1 (enExample)
PT (1) PT1363726E (enExample)
RU (1) RU2296002C2 (enExample)
SI (1) SI1363726T1 (enExample)
SK (1) SK287659B6 (enExample)
TR (1) TR200401219T4 (enExample)
WO (1) WO2002068107A2 (enExample)
ZA (1) ZA200306369B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102458676A (zh) * 2009-06-25 2012-05-16 纳幕尔杜邦公司 喷涂装置及其用途

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW586963B (en) 2001-07-20 2004-05-11 Nektar Therapeutics Uk Ltd Method and apparatus for preparing target substance in particulate form and fluid inlet assembly for said apparatus
KR100887429B1 (ko) * 2001-10-22 2009-03-09 돔페 파르마 에스.피.에이. 초임계 유체 공정: 단백질 미세입자의 제조 및 그의 안정화
GB0300338D0 (en) * 2003-01-08 2003-02-05 Bradford Particle Design Ltd Particle formation
GB0300339D0 (en) * 2003-01-08 2003-02-05 Bradford Particle Design Ltd Particle formation
EP1683560A4 (en) * 2003-06-10 2008-10-01 Taisho Pharmaceutical Co Ltd RADIAL SPHERICAL CRYSTALLIZATION PRODUCT, METHOD FOR THE PRODUCTION THEREOF, AND THE DRY POWDER CONTAINING THE CRYSTALLIZATION PRODUCT
JP5016785B2 (ja) * 2004-12-28 2012-09-05 株式会社奈良機械製作所 微細粒子の生成装置
JP4896418B2 (ja) * 2005-03-23 2012-03-14 富士フイルム株式会社 有機微粒子およびその分散液の製造方法、ならびにそれにより得られる有機微粒子およびその分散液
US8240065B2 (en) * 2007-02-05 2012-08-14 Praxair Technology, Inc. Freeze-dryer and method of controlling the same
ES2336524B1 (es) * 2007-10-17 2011-02-14 Activery Biotech, S.L. Procedimiento para la preparacion de particulas.
US8585943B2 (en) * 2007-12-07 2013-11-19 Xspray Microparticles Ab Method and arrangement for the production of particles
CN101444709B (zh) * 2008-12-05 2010-06-02 厦门大学 一种以超临界二氧化碳从水溶液中获取固体颗粒的方法
KR101143926B1 (ko) 2009-02-10 2012-05-11 한국식품연구원 초임계유체 시스템에 의한 고추 올레오레진캡시컴나노체의 제조방법
US20110024354A1 (en) * 2009-07-30 2011-02-03 General Electric Company Desalination system and method
CN103037961A (zh) * 2010-06-14 2013-04-10 X喷雾微粒公司 用于生产微粒的装置与方法
CN102019241B (zh) * 2010-10-22 2012-08-01 山东大学 一种超临界流体纳微米材料制备用组合喷嘴
WO2014081881A2 (en) 2012-11-20 2014-05-30 Andrew Paul Joseph Fluid-based extractor
US9908062B2 (en) 2012-11-20 2018-03-06 Andrew Paul Joseph Extraction apparatus and method
US9925512B2 (en) 2013-03-14 2018-03-27 Crititech, Inc. Equipment assembly for and method of processing particles
US8778181B1 (en) 2013-03-14 2014-07-15 Crititech, Inc. Equipment assembly for and method of processing particles
WO2015053857A2 (en) * 2013-10-10 2015-04-16 New York University Efficient collection of nanoparticles
RU2590561C1 (ru) * 2015-03-26 2016-07-10 Сергей Александрович Сошин Установка для получения мелкодисперсных порошков и способ получения мелкодисперсных порошков
US10206873B1 (en) 2017-08-04 2019-02-19 Colorado Can Llc Dry powder formation using a variably constrained, divided pathway for mixing fluid streams
CN115253893A (zh) * 2022-07-25 2022-11-01 安徽科幂仪器有限公司 一种少量纳米极性颗粒的超临界二氧化碳制备装置及方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576111A (en) * 1983-01-27 1986-03-18 Domino Printing Sciences Plc Marking jet discharging head
WO1996000610A1 (en) * 1994-06-30 1996-01-11 University Of Bradford Method and apparatus for the formation of particles
GB2322326A (en) * 1997-02-21 1998-08-26 Bradford Particle Design Ltd Controlled formation of particles using supercritical fluids
US5874029A (en) * 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
WO2000010739A1 (en) * 1998-08-07 2000-03-02 Urho Anttonen Process and device for treating surfaces

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES481924A1 (es) * 1978-06-28 1980-09-01 Gen Foods Ltd Un procedimiento mejorado para obtener un producto alimenti-cio secado por pulverizacion, tal como cafe, destrina y si- milares.
US4416600A (en) 1982-02-10 1983-11-22 Griff Williams Co. Apparatus for producing high purity metal powders
US6063910A (en) * 1991-11-14 2000-05-16 The Trustees Of Princeton University Preparation of protein microparticles by supercritical fluid precipitation
US5301664A (en) * 1992-03-06 1994-04-12 Sievers Robert E Methods and apparatus for drug delivery using supercritical solutions
WO1994008599A1 (en) * 1992-10-14 1994-04-28 The Regents Of The University Of Colorado Ion-pairing of drugs for improved efficacy and delivery
GB9313642D0 (en) 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
GB9313650D0 (en) 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
US5601781A (en) * 1995-06-22 1997-02-11 General Electric Company Close-coupled atomization utilizing non-axisymmetric melt flow
US5804066A (en) * 1996-02-08 1998-09-08 Aerojet-General Corporation Injector for SCWO reactor
JP3986086B2 (ja) 1996-03-01 2007-10-03 ザ ユニバーシティ オブ カンザス 近臨界および超臨界反溶媒を用いる粒子析出方法および被覆方法
US5833891A (en) * 1996-10-09 1998-11-10 The University Of Kansas Methods for a particle precipitation and coating using near-critical and supercritical antisolvents
US6116516A (en) * 1996-05-13 2000-09-12 Universidad De Sevilla Stabilized capillary microjet and devices and methods for producing same
JPH10192670A (ja) * 1996-12-27 1998-07-28 Inoue Seisakusho:Kk 超臨界状態を用いた分散方法及び分散装置
GB9810559D0 (en) * 1998-05-15 1998-07-15 Bradford Particle Design Ltd Method and apparatus for particle formation
GB9828204D0 (en) 1998-12-21 1999-02-17 Smithkline Beecham Plc Process
SE9901059L (sv) * 1999-03-22 2000-09-23 Johan Carlfors Metod för framställning av partiklar
SE9901667D0 (sv) 1999-05-07 1999-05-07 Astra Ab Method and device for forming particles
JP4874483B2 (ja) * 1999-06-09 2012-02-15 ロバート イー． シーバース 超臨界流体補助ネブライゼーション及びバブル乾燥
GB9915975D0 (en) * 1999-07-07 1999-09-08 Bradford Particle Design Ltd Method for the formation of particles
TW586963B (en) 2001-07-20 2004-05-11 Nektar Therapeutics Uk Ltd Method and apparatus for preparing target substance in particulate form and fluid inlet assembly for said apparatus
GB0300339D0 (en) * 2003-01-08 2003-02-05 Bradford Particle Design Ltd Particle formation
CN1238101C (zh) * 2003-10-10 2006-01-25 大连理工大学 用超临界反溶剂过程制备超细粉体的结晶釜

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576111A (en) * 1983-01-27 1986-03-18 Domino Printing Sciences Plc Marking jet discharging head
WO1996000610A1 (en) * 1994-06-30 1996-01-11 University Of Bradford Method and apparatus for the formation of particles
US5874029A (en) * 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
GB2322326A (en) * 1997-02-21 1998-08-26 Bradford Particle Design Ltd Controlled formation of particles using supercritical fluids
WO2000010739A1 (en) * 1998-08-07 2000-03-02 Urho Anttonen Process and device for treating surfaces

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102458676A (zh) * 2009-06-25 2012-05-16 纳幕尔杜邦公司 喷涂装置及其用途

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DK1363726T3 (da) 2004-12-06
PL205820B1 (pl) 2010-05-31
TR200401219T3 (enExample) 2004-08-23
RU2003125645A (ru) 2005-03-10
WO2002068107A8 (en) 2003-10-16
JP2004526560A (ja) 2004-09-02
HU228083B1 (en) 2012-10-29
IL157346A (en) 2006-12-10
KR100858956B1 (ko) 2008-09-17
NZ528082A (en) 2004-05-28
KR20030092000A (ko) 2003-12-03
ES2223034T3 (es) 2005-02-16
SK287659B6 (sk) 2011-05-06
PL363529A1 (en) 2004-11-29
ZA200306369B (en) 2004-05-03
BR0207570A (pt) 2004-04-27
CA2438275A1 (en) 2002-09-06
IL157346A0 (en) 2004-02-19
EE200300412A (et) 2003-12-15
DE60201127D1 (de) 2004-10-07
HK1063440A1 (zh) 2004-12-31
CZ20032596A3 (cs) 2004-07-14
DE60201127T2 (de) 2005-09-01
EE05100B1 (et) 2008-12-15
ATE274995T1 (de) 2004-09-15
SI1363726T1 (en) 2005-02-28
AU2002236021B2 (en) 2006-11-16
NO20033780L (no) 2003-08-26
CN1494455A (zh) 2004-05-05
CZ301857B6 (cs) 2010-07-14
TR200401219T4 (tr) 2004-10-21
EP1363726B1 (en) 2004-09-01
CA2438275C (en) 2010-05-25
US7175886B2 (en) 2007-02-13
US7635442B2 (en) 2009-12-22
HUP0303221A2 (hu) 2003-12-29
EP1363726A2 (en) 2003-11-26
JP4405153B2 (ja) 2010-01-27
WO2002068107A2 (en) 2002-09-06
MXPA03007541A (es) 2004-10-15
NO331676B1 (no) 2012-02-20
WO2002068107A3 (en) 2002-12-05
SK11892003A3 (sk) 2004-02-03
US20080093757A1 (en) 2008-04-24
PT1363726E (pt) 2004-11-30
RU2296002C2 (ru) 2007-03-27
BR0207570B1 (pt) 2013-02-05
US20040107901A1 (en) 2004-06-10
NO20033780D0 (no) 2003-08-26

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