DE60201127D1 - Apparat und methode zur bildung von mikro- und submikropartikeln - Google Patents

Apparat und methode zur bildung von mikro- und submikropartikeln

Info

Publication number
DE60201127D1
DE60201127D1 DE60201127T DE60201127T DE60201127D1 DE 60201127 D1 DE60201127 D1 DE 60201127D1 DE 60201127 T DE60201127 T DE 60201127T DE 60201127 T DE60201127 T DE 60201127T DE 60201127 D1 DE60201127 D1 DE 60201127D1
Authority
DE
Germany
Prior art keywords
supercritical fluid
flow
solution
submicroparticles
micron
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60201127T
Other languages
English (en)
Other versions
DE60201127T2 (de
Inventor
Re Giovanni Del
Matteo Putrignano
Giacomo Gabriele Di
Palma Cesare Di
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dompe SpA
Original Assignee
Dompe SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8176607&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60201127(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dompe SpA filed Critical Dompe SpA
Publication of DE60201127D1 publication Critical patent/DE60201127D1/de
Application granted granted Critical
Publication of DE60201127T2 publication Critical patent/DE60201127T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02Spray pistols; Apparatus for discharge
    • B05B7/08Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Glanulating (AREA)
  • Disintegrating Or Milling (AREA)
  • Steroid Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
DE60201127T 2001-02-26 2002-02-26 Vorrichtung und Verfahren zur Bildung von Mikrometer- und Submikrometerteilchen Expired - Lifetime DE60201127T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01104705 2001-02-26
EP01104705 2001-02-26
PCT/GB2002/000840 WO2002068107A2 (en) 2001-02-26 2002-02-26 Apparatus and method for micron and submicron particle formation

Publications (2)

Publication Number Publication Date
DE60201127D1 true DE60201127D1 (de) 2004-10-07
DE60201127T2 DE60201127T2 (de) 2005-09-01

Family

ID=8176607

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60201127T Expired - Lifetime DE60201127T2 (de) 2001-02-26 2002-02-26 Vorrichtung und Verfahren zur Bildung von Mikrometer- und Submikrometerteilchen

Country Status (28)

Country Link
US (2) US7175886B2 (de)
EP (1) EP1363726B1 (de)
JP (1) JP4405153B2 (de)
KR (1) KR100858956B1 (de)
CN (1) CN100531886C (de)
AT (1) ATE274995T1 (de)
AU (1) AU2002236021B2 (de)
BR (1) BR0207570B1 (de)
CA (1) CA2438275C (de)
CZ (1) CZ301857B6 (de)
DE (1) DE60201127T2 (de)
DK (1) DK1363726T3 (de)
EE (1) EE05100B1 (de)
ES (1) ES2223034T3 (de)
HK (1) HK1063440A1 (de)
HU (1) HU228083B1 (de)
IL (2) IL157346A0 (de)
MX (1) MXPA03007541A (de)
NO (1) NO331676B1 (de)
NZ (1) NZ528082A (de)
PL (1) PL205820B1 (de)
PT (1) PT1363726E (de)
RU (1) RU2296002C2 (de)
SI (1) SI1363726T1 (de)
SK (1) SK287659B6 (de)
TR (1) TR200401219T4 (de)
WO (1) WO2002068107A2 (de)
ZA (1) ZA200306369B (de)

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TW586963B (en) 2001-07-20 2004-05-11 Nektar Therapeutics Uk Ltd Method and apparatus for preparing target substance in particulate form and fluid inlet assembly for said apparatus
WO2003035673A1 (en) * 2001-10-22 2003-05-01 Dompe S.P.A. Supercritical fluids processing: preparation of protein microparticles and their stabilisation
GB0300339D0 (en) * 2003-01-08 2003-02-05 Bradford Particle Design Ltd Particle formation
GB0300338D0 (en) * 2003-01-08 2003-02-05 Bradford Particle Design Ltd Particle formation
WO2004110585A1 (ja) * 2003-06-10 2004-12-23 Taisho Pharmaceutical Co., Ltd. 放射球状晶析物およびその製造方法並びにこれを利用するドライパウダー製剤
JP5016785B2 (ja) * 2004-12-28 2012-09-05 株式会社奈良機械製作所 微細粒子の生成装置
JP4896418B2 (ja) * 2005-03-23 2012-03-14 富士フイルム株式会社 有機微粒子およびその分散液の製造方法、ならびにそれにより得られる有機微粒子およびその分散液
US8240065B2 (en) * 2007-02-05 2012-08-14 Praxair Technology, Inc. Freeze-dryer and method of controlling the same
ES2336524B1 (es) 2007-10-17 2011-02-14 Activery Biotech, S.L. Procedimiento para la preparacion de particulas.
US8585943B2 (en) 2007-12-07 2013-11-19 Xspray Microparticles Ab Method and arrangement for the production of particles
CN101444709B (zh) * 2008-12-05 2010-06-02 厦门大学 一种以超临界二氧化碳从水溶液中获取固体颗粒的方法
KR101143926B1 (ko) 2009-02-10 2012-05-11 한국식품연구원 초임계유체 시스템에 의한 고추 올레오레진캡시컴나노체의 제조방법
EP2445648A1 (de) * 2009-06-25 2012-05-02 E. I. du Pont de Nemours and Company Sprayvorrichtung und ihre verwendung
US20110024354A1 (en) * 2009-07-30 2011-02-03 General Electric Company Desalination system and method
CN103037961A (zh) * 2010-06-14 2013-04-10 X喷雾微粒公司 用于生产微粒的装置与方法
CN102019241B (zh) * 2010-10-22 2012-08-01 山东大学 一种超临界流体纳微米材料制备用组合喷嘴
WO2014081881A2 (en) * 2012-11-20 2014-05-30 Andrew Paul Joseph Fluid-based extractor
US9908062B2 (en) 2012-11-20 2018-03-06 Andrew Paul Joseph Extraction apparatus and method
US8778181B1 (en) 2013-03-14 2014-07-15 Crititech, Inc. Equipment assembly for and method of processing particles
US9925512B2 (en) 2013-03-14 2018-03-27 Crititech, Inc. Equipment assembly for and method of processing particles
US20160244547A1 (en) * 2013-10-10 2016-08-25 New York University Efficient collection of nanoparticles
RU2590561C1 (ru) * 2015-03-26 2016-07-10 Сергей Александрович Сошин Установка для получения мелкодисперсных порошков и способ получения мелкодисперсных порошков
US10206873B1 (en) 2017-08-04 2019-02-19 Colorado Can Llc Dry powder formation using a variably constrained, divided pathway for mixing fluid streams
CN115253893A (zh) * 2022-07-25 2022-11-01 安徽科幂仪器有限公司 一种少量纳米极性颗粒的超临界二氧化碳制备装置及方法

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ES481924A1 (es) * 1978-06-28 1980-09-01 Gen Foods Ltd Un procedimiento mejorado para obtener un producto alimenti-cio secado por pulverizacion, tal como cafe, destrina y si- milares.
US4416600A (en) 1982-02-10 1983-11-22 Griff Williams Co. Apparatus for producing high purity metal powders
DE3302617C2 (de) * 1983-01-27 1987-04-23 Domino Printing Sciences Plc, Cambridge Farbspritzkopf
US6063910A (en) 1991-11-14 2000-05-16 The Trustees Of Princeton University Preparation of protein microparticles by supercritical fluid precipitation
US5301664A (en) * 1992-03-06 1994-04-12 Sievers Robert E Methods and apparatus for drug delivery using supercritical solutions
WO1994008599A1 (en) * 1992-10-14 1994-04-28 The Regents Of The University Of Colorado Ion-pairing of drugs for improved efficacy and delivery
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
GB9313650D0 (en) 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
GB9413202D0 (en) * 1994-06-30 1994-08-24 Univ Bradford Method and apparatus for the formation of particles
US5601781A (en) 1995-06-22 1997-02-11 General Electric Company Close-coupled atomization utilizing non-axisymmetric melt flow
US5804066A (en) 1996-02-08 1998-09-08 Aerojet-General Corporation Injector for SCWO reactor
WO1997031691A1 (en) 1996-03-01 1997-09-04 The University Of Kansas Methods and apparatus for particle precipitation and coating using near-critical and supercritical antisolvents
US5874029A (en) 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
US5833891A (en) * 1996-10-09 1998-11-10 The University Of Kansas Methods for a particle precipitation and coating using near-critical and supercritical antisolvents
US6197835B1 (en) 1996-05-13 2001-03-06 Universidad De Sevilla Device and method for creating spherical particles of uniform size
JPH10192670A (ja) 1996-12-27 1998-07-28 Inoue Seisakusho:Kk 超臨界状態を用いた分散方法及び分散装置
GB9703673D0 (en) 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
GB9810559D0 (en) * 1998-05-15 1998-07-15 Bradford Particle Design Ltd Method and apparatus for particle formation
FI981716A0 (fi) * 1998-08-07 1998-08-07 Urho Anttonen Menetelmä ja laitteisto pintojen käsittelemiseksi
GB9828204D0 (en) 1998-12-21 1999-02-17 Smithkline Beecham Plc Process
SE9901667D0 (sv) 1999-05-07 1999-05-07 Astra Ab Method and device for forming particles
CN1198593C (zh) * 1999-06-09 2005-04-27 罗伯特·E·希弗斯 超临界流体辅助的喷雾和鼓泡干燥
GB9915975D0 (en) * 1999-07-07 1999-09-08 Bradford Particle Design Ltd Method for the formation of particles
TW586963B (en) 2001-07-20 2004-05-11 Nektar Therapeutics Uk Ltd Method and apparatus for preparing target substance in particulate form and fluid inlet assembly for said apparatus
GB0300339D0 (en) * 2003-01-08 2003-02-05 Bradford Particle Design Ltd Particle formation
CN1238101C (zh) * 2003-10-10 2006-01-25 大连理工大学 用超临界反溶剂过程制备超细粉体的结晶釜

Also Published As

Publication number Publication date
US20080093757A1 (en) 2008-04-24
SK11892003A3 (sk) 2004-02-03
CA2438275C (en) 2010-05-25
ZA200306369B (en) 2004-05-03
US7635442B2 (en) 2009-12-22
CN1494455A (zh) 2004-05-05
WO2002068107A3 (en) 2002-12-05
RU2296002C2 (ru) 2007-03-27
WO2002068107A2 (en) 2002-09-06
CA2438275A1 (en) 2002-09-06
MXPA03007541A (es) 2004-10-15
PL363529A1 (en) 2004-11-29
DK1363726T3 (da) 2004-12-06
HU228083B1 (en) 2012-10-29
WO2002068107A8 (en) 2003-10-16
EE200300412A (et) 2003-12-15
IL157346A0 (en) 2004-02-19
NO331676B1 (no) 2012-02-20
BR0207570A (pt) 2004-04-27
CN100531886C (zh) 2009-08-26
US7175886B2 (en) 2007-02-13
ES2223034T3 (es) 2005-02-16
TR200401219T4 (tr) 2004-10-21
HK1063440A1 (en) 2004-12-31
NO20033780L (no) 2003-08-26
AU2002236021B2 (en) 2006-11-16
EP1363726A2 (de) 2003-11-26
EE05100B1 (et) 2008-12-15
KR100858956B1 (ko) 2008-09-17
PT1363726E (pt) 2004-11-30
US20040107901A1 (en) 2004-06-10
BR0207570B1 (pt) 2013-02-05
JP4405153B2 (ja) 2010-01-27
IL157346A (en) 2006-12-10
NO20033780D0 (no) 2003-08-26
SI1363726T1 (en) 2005-02-28
JP2004526560A (ja) 2004-09-02
CZ301857B6 (cs) 2010-07-14
KR20030092000A (ko) 2003-12-03
DE60201127T2 (de) 2005-09-01
RU2003125645A (ru) 2005-03-10
NZ528082A (en) 2004-05-28
PL205820B1 (pl) 2010-05-31
TR200401219T3 (de) 2004-08-23
ATE274995T1 (de) 2004-09-15
CZ20032596A3 (cs) 2004-07-14
SK287659B6 (sk) 2011-05-06
EP1363726B1 (de) 2004-09-01
HUP0303221A2 (hu) 2003-12-29

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8365 Fully valid after opposition proceedings
8328 Change in the person/name/address of the agent

Representative=s name: KUDLEK & GRUNERT PATENTANWAELTE PARTNERSCHAFT, 803