CN100422141C - 制备2-二卤代酰基-3-氨基丙烯酸酯以及3-二卤代甲基吡唑-4-羧酸酯的方法 - Google Patents

制备2-二卤代酰基-3-氨基丙烯酸酯以及3-二卤代甲基吡唑-4-羧酸酯的方法 Download PDF

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Publication number
CN100422141C
CN100422141C CNB2004800312031A CN200480031203A CN100422141C CN 100422141 C CN100422141 C CN 100422141C CN B2004800312031 A CNB2004800312031 A CN B2004800312031A CN 200480031203 A CN200480031203 A CN 200480031203A CN 100422141 C CN100422141 C CN 100422141C
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alkyl
formula
another
chlorine
toluene
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Chinese (zh)
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CN1871204A (zh
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R·兰茨施
W·耶尔格斯
S·帕奇诺克
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Bayer Intellectual Property GmbH
Bayer CropScience AG
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Bayer CropScience AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNB2004800312031A 2003-10-23 2004-10-12 制备2-二卤代酰基-3-氨基丙烯酸酯以及3-二卤代甲基吡唑-4-羧酸酯的方法 Expired - Lifetime CN100422141C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10349500A DE10349500A1 (de) 2003-10-23 2003-10-23 Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern
DE10349500.2 2003-10-23

Publications (2)

Publication Number Publication Date
CN1871204A CN1871204A (zh) 2006-11-29
CN100422141C true CN100422141C (zh) 2008-10-01

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CNB2004800312031A Expired - Lifetime CN100422141C (zh) 2003-10-23 2004-10-12 制备2-二卤代酰基-3-氨基丙烯酸酯以及3-二卤代甲基吡唑-4-羧酸酯的方法

Country Status (14)

Country Link
US (1) US7358387B2 (https=)
EP (1) EP1678119B1 (https=)
JP (1) JP4725977B2 (https=)
KR (1) KR101116686B1 (https=)
CN (1) CN100422141C (https=)
AT (1) ATE494274T1 (https=)
BR (1) BRPI0415855B1 (https=)
DE (2) DE10349500A1 (https=)
DK (1) DK1678119T3 (https=)
IL (1) IL175024A (https=)
IN (1) IN2006DE01793A (https=)
MX (1) MXPA06004339A (https=)
TW (1) TWI363050B (https=)
WO (1) WO2005042468A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102471278A (zh) * 2009-07-28 2012-05-23 先正达参股股份有限公司 关于吡唑的烷基化方法

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KR101733625B1 (ko) 2008-12-11 2017-05-10 시오노기세야쿠 가부시키가이샤 카르바모일피리돈 ｈｉｖ 인테그라제 억제제 및 중간체의 합성
TWI518084B (zh) 2009-03-26 2016-01-21 鹽野義製藥股份有限公司 哌喃酮與吡啶酮衍生物之製造方法
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EP2496561B1 (en) 2009-11-05 2014-06-04 Basf Se Process for preparing aminale and their use for preparing 1,3-disubstituted pyrazole compounds
TWI582097B (zh) 2010-03-23 2017-05-11 Ｖｉｉｖ醫療保健公司 製備胺甲醯吡啶酮衍生物及中間體之方法
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JP5605104B2 (ja) * 2010-09-10 2014-10-15 セントラル硝子株式会社 ピラゾール化合物の製造方法
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JP5915004B2 (ja) * 2011-06-22 2016-05-11 セントラル硝子株式会社 ピラゾール化合物の製造方法
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CN102731402A (zh) * 2012-06-29 2012-10-17 上海康鹏化学有限公司 3-三氟甲基吡唑-4-羧酸和3-二氟甲基吡唑-4-羧酸的制备方法
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JP6431088B2 (ja) * 2014-03-24 2018-11-28 バイエル・クロップサイエンス・アクチェンゲゼルシャフト α，α−ジハロアミン類およびケチミン類からの３，５−ビス（ハロアルキル）ピラゾール誘導体の製造方法
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CN104529899A (zh) * 2014-12-19 2015-04-22 浙江泰达作物科技有限公司 高区域选择性制备1-烷基-3-卤代烷基吡唑衍生物的方法
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CN109689629B (zh) 2016-09-21 2022-11-29 拜耳作物科学股份公司 制备3-氟烷基-5-吡唑羧酸酯和3-氟烷基-5-吡唑羧酸的方法
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CN111116364B (zh) * 2019-12-30 2022-11-11 浙江本立科技股份有限公司 2-多卤代乙酰基-3-烷氧基丙烯酸酯的制备方法
CN113912541A (zh) * 2021-10-29 2022-01-11 南通宝凯药业有限公司 一种3-二氟甲基-1-甲基-1h-吡唑-4-羧酸的制备方法
CN114195715B (zh) * 2021-12-31 2024-05-10 福建永晶科技股份有限公司 1-甲基-3-二氟甲基-4-吡唑酸和1-甲基-3-三氟甲基-4-吡唑酸的制备方法
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CN102471278A (zh) * 2009-07-28 2012-05-23 先正达参股股份有限公司 关于吡唑的烷基化方法
CN102471278B (zh) * 2009-07-28 2015-04-01 先正达参股股份有限公司 关于吡唑的烷基化方法

Also Published As

Publication number Publication date
IL175024A0 (en) 2006-08-20
CN1871204A (zh) 2006-11-29
ATE494274T1 (de) 2011-01-15
IN2006DE01793A (https=) 2007-08-10
WO2005042468A1 (de) 2005-05-12
TWI363050B (en) 2012-05-01
DE10349500A1 (de) 2005-06-02
KR20060109901A (ko) 2006-10-23
KR101116686B1 (ko) 2012-02-22
JP2007509850A (ja) 2007-04-19
MXPA06004339A (es) 2006-06-05
IL175024A (en) 2011-05-31
JP4725977B2 (ja) 2011-07-13
EP1678119B1 (de) 2011-01-05
TW200526550A (en) 2005-08-16
BRPI0415855B1 (pt) 2013-11-05
BRPI0415855A (pt) 2007-01-09
DE502004012095D1 (de) 2011-02-17
US7358387B2 (en) 2008-04-15
DK1678119T3 (da) 2011-05-02
EP1678119A1 (de) 2006-07-12
US20060252944A1 (en) 2006-11-09

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