CN100349857C - 氨基取代的羟苯基二苯甲酮衍生物 - Google Patents

氨基取代的羟苯基二苯甲酮衍生物 Download PDF

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Publication number
CN100349857C
CN100349857C CNB2003801058851A CN200380105885A CN100349857C CN 100349857 C CN100349857 C CN 100349857C CN B2003801058851 A CNB2003801058851 A CN B2003801058851A CN 200380105885 A CN200380105885 A CN 200380105885A CN 100349857 C CN100349857 C CN 100349857C
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CN
China
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alkyl
formula
group
compound
alkylene
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Expired - Lifetime
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CNB2003801058851A
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English (en)
Chinese (zh)
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CN1726184A (zh
Inventor
J·哈斯
T·埃利斯
E·博尔索斯
S·米勒
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BASF Schweiz AG
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Ciba Spezialitaetenchemie Holding AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/40—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB2003801058851A 2002-12-12 2003-12-03 氨基取代的羟苯基二苯甲酮衍生物 Expired - Lifetime CN100349857C (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
EP02406093.1 2002-12-12
EP02406093 2002-12-12
CH20031113/03 2003-06-25
CH1113/03 2003-06-25
CH11132003 2003-06-25
EP03102297.3 2003-07-25
EP03102297 2003-07-25
PCT/EP2003/050937 WO2004052837A2 (en) 2002-12-12 2003-12-03 Amino substituted hydroxyphenyl benzophenone derivatives

Publications (2)

Publication Number Publication Date
CN1726184A CN1726184A (zh) 2006-01-25
CN100349857C true CN100349857C (zh) 2007-11-21

Family

ID=32511848

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB2003801058851A Expired - Lifetime CN100349857C (zh) 2002-12-12 2003-12-03 氨基取代的羟苯基二苯甲酮衍生物

Country Status (11)

Country Link
US (1) US7374749B2 (https=)
EP (1) EP1569893B1 (https=)
JP (1) JP4566907B2 (https=)
KR (1) KR101057747B1 (https=)
CN (1) CN100349857C (https=)
AT (1) ATE553076T1 (https=)
AU (1) AU2003298343B2 (https=)
BR (1) BR0316607B1 (https=)
ES (1) ES2381872T3 (https=)
MX (1) MX271169B (https=)
WO (1) WO2004052837A2 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2412866A (en) * 2004-04-02 2005-10-12 Ciba Sc Holding Ag Amino-benzophenone UV filter formulations for the prevention of tanning
DE102005023634A1 (de) * 2005-05-19 2006-11-23 Beiersdorf Ag Wirkstoffkombinationen aus 2-(4'-(Diethylamino)-2'-hydoxybenzoyl)-benzoesäurehexylester und einem oder mehreren Glucosylglyceriden
GB2433439A (en) 2005-12-21 2007-06-27 Ciba Sc Holding Ag Use of transmission dyes to protect human skin from UV radiation
US7999128B2 (en) * 2006-02-09 2011-08-16 Basf Se Hydroxybenzophenone derivatives
DE102007005335A1 (de) * 2007-02-01 2008-08-07 Beiersdorf Ag Lichtschutzzubereitung mit einer Kombination von Mikropigmenten
DE102007005334A1 (de) 2007-02-01 2008-08-07 Beiersdorf Ag Piperazinderivate in diolhaltigen kosmetischen Zubereitungen
DE102007005333A1 (de) * 2007-02-01 2008-08-07 Beiersdorf Ag Organische Mikropigmente in kosmetischen Lichtschutzemulsionen
DE102007005336A1 (de) * 2007-02-01 2008-08-07 Beiersdorf Ag UV-Filterkombination mit Piperazinderivaten
US20100143274A1 (en) * 2007-03-07 2010-06-10 Ciba Corporation Use of amines and amides for the stabilization of organic micronized uv absorbers
ES2603878T3 (es) * 2007-05-08 2017-03-01 Basf Se Modificaciones cristalinas de colorantes de transmisión
US8393556B2 (en) * 2007-07-04 2013-03-12 Basf Se Preparation of nanoscalar UV absorbers
DE102007038414A1 (de) 2007-08-09 2009-02-12 Beiersdorf Ag Neue kosmetische Emulgatorkombination
KR20150132598A (ko) * 2007-11-29 2015-11-25 바스프 에스이 미세화된 유기 ｕｖ 흡수제에 대한 분쇄 조제
US20100322880A1 (en) * 2008-02-06 2010-12-23 Merck Patent Gmbh Uva filters based on ascorbic acid derivatives
EP2496207A1 (en) * 2009-11-05 2012-09-12 L'Oréal Cosmetic compositions comprising an ester derived from 4-carboxy-2-pyrrolidinone and a lipophilic screening agent; use of said derivative as a solvent for a benzophenone lipophilic screening agent
MX348556B (es) * 2011-01-28 2017-06-16 Momentive Performance Mat Gmbh Composicion cosmetica fotoprotectora de rayos ultravioleta.
US9203541B2 (en) 2012-09-28 2015-12-01 Intel Corporation Methods and apparatus for multiphase sampling of modulated light
CN103059168B (zh) * 2013-01-17 2014-09-17 长沙新宇高分子科技有限公司 一种二苯甲酮类光引发剂及其制备方法
MX368523B (es) * 2013-06-27 2019-10-07 Dsm Ip Assets Bv Metodo para producir benzoatos de 2-(4-n, n-dialquilamino-2-hidrox ibenzoilo).
CN105517990B (zh) * 2013-08-12 2018-10-02 太阳化学公司 低聚氨基酮及其作为光敏引发剂的用途
JP6580788B2 (ja) 2015-12-02 2019-09-25 ノバルティス アーゲー 水溶性ｕｖ吸収化合物およびその使用
CA3116257C (en) 2016-02-22 2024-01-16 Alcon Inc. Uv-absorbing vinylic monomers and uses thereof
SG11202000230VA (en) 2017-07-11 2020-02-27 Vertex Pharma Carboxamides as modulators of sodium channels
JP7015775B2 (ja) * 2018-11-28 2022-02-03 芳弘 二村 遺伝子修復作用を呈するポリフェノール誘導体
US12441703B2 (en) 2019-01-10 2025-10-14 Vertex Pharmaceuticals Incorporated Carboxamides as modulators of sodium channels
WO2020146612A1 (en) 2019-01-10 2020-07-16 Vertex Pharmaceuticals Incorporated Esters and carbamates as modulators of sodium channels
WO2023247598A1 (en) * 2022-06-22 2023-12-28 Skinosive Multi-photoprotective compounds and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1046391A2 (de) * 1999-04-20 2000-10-25 Basf Aktiengesellschaft Verwendung von aminosubstituierten Hydroxybenzophenonen als photostabile UV-Filter in kosmetischen und pharmazeutischen Zubereitungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19855649A1 (de) * 1998-12-03 2000-06-08 Basf Ag Dimere alpha-Alkyl-Styrolderivate als photostabile UV-Filter in kosmetischen und pharmazeutischen Zubereitungen
DE10113058A1 (de) * 2001-03-15 2002-09-19 Basf Ag Verwendung von Lichtschutzmittelkombinationen, die als wesentlichen Bestandteil 2-(4-Alkoxy-anilinomethylen)-malonsäure-dialkylester enthalten als photostabile UV-Filter in kosmetischen und pharmazeutischen Zubereitungen
FR2833164B1 (fr) * 2001-12-07 2004-07-16 Oreal Compositions cosmetiques antisolaires a base d'un melange synergique de filtres et utilisations
JP2015098471A (ja) * 2013-11-18 2015-05-28 東洋合成工業株式会社 化学種発生向上試剤

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1046391A2 (de) * 1999-04-20 2000-10-25 Basf Aktiengesellschaft Verwendung von aminosubstituierten Hydroxybenzophenonen als photostabile UV-Filter in kosmetischen und pharmazeutischen Zubereitungen

Also Published As

Publication number Publication date
BR0316607A (pt) 2005-10-11
JP2006509834A (ja) 2006-03-23
US7374749B2 (en) 2008-05-20
KR101057747B1 (ko) 2011-08-19
BR0316607B1 (pt) 2014-12-23
AU2003298343A1 (en) 2004-06-30
MXPA05006197A (es) 2005-08-19
ATE553076T1 (de) 2012-04-15
ES2381872T3 (es) 2012-06-01
US20060018846A1 (en) 2006-01-26
KR20050085469A (ko) 2005-08-29
JP4566907B2 (ja) 2010-10-20
CN1726184A (zh) 2006-01-25
EP1569893B1 (en) 2012-04-11
AU2003298343B2 (en) 2010-02-25
WO2004052837A2 (en) 2004-06-24
EP1569893A2 (en) 2005-09-07
WO2004052837A3 (en) 2004-09-10
MX271169B (es) 2009-10-23

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Granted publication date: 20071121