BR0316607A - Derivados de hidroxifenil benzofenona substituìdos com amino - Google Patents

Derivados de hidroxifenil benzofenona substituìdos com amino

Info

Publication number
BR0316607A
BR0316607A BR0316607-4A BR0316607A BR0316607A BR 0316607 A BR0316607 A BR 0316607A BR 0316607 A BR0316607 A BR 0316607A BR 0316607 A BR0316607 A BR 0316607A
Authority
BR
Brazil
Prior art keywords
sub
alkyl
radical
optionally substituted
amino
Prior art date
Application number
BR0316607-4A
Other languages
English (en)
Other versions
BR0316607B1 (pt
Inventor
Juerg Haase
Thomas Ehlis
Elek Borsos
Stefan Mueller
Original Assignee
Ciba Sc Holding Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Sc Holding Ag filed Critical Ciba Sc Holding Ag
Publication of BR0316607A publication Critical patent/BR0316607A/pt
Publication of BR0316607B1 publication Critical patent/BR0316607B1/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/40—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)

Abstract

"DERIVADOS DE HIDROXIFENIL BENZOFENONA SUBSTITUìDOS COM AMINO". A presente invenção refere-se a derivados de hidroxifenil benzofenona substituídos com amino da fórmula na qual R~ 1~ e R~ 2~ de modo independente um do outro são: C~ 1~-C~ 20~ alquila; C~ 2~-C~ 20~ alquenila; C~ 3-C~ 10~ cicloalquila; C~ 3~-C~ 10~ cicloalquenila; ou R~ 1~ e R~ 2~ em conjunto com o átomo de nitrogênio de ligação formam um anel heterocíclico de 5- ou 6- membros; n~ 1~ é um número a partir de 1 até 4; quando n~ 1~ = 1, R~ 2~ é um radical heterocíclico saturado ou não saturado; hidróxi C~ 1~-C~ 5~ alquila; cicloalquila substituída de forma opcional com uma ou mais C~ 1~-C~ 5~ alquila; fenila substituída de forma opcional com um radical heterocíclico, amino carbonil ou C~ 1~-C~ 5~ alquil carbóxi; quando n~ 1~, for 2 R3 é um radical alquileno-, cicloalquileno, alquenileno que é substituído de forma opcional por um grupo carbonil- ou carbóxi; ou R3 em conjunto com A forma um radical bivalente da fórmula na qual n2 é um número a partir de 1 até 3; quando n, for 3, R3 é um radical alcantriíla; quando n, for 4, R~ 3~ é um radical alcantetraíla; A é -O- ou -N(R~ 5~)=; e R~ 5~ é hidrogênio; C~ 1~-C~ 5~ alquila; ou hidróxi C~ 1~-C~ 5~ alquila. Os compostos são úteis como filtros de radiação ultravioleta em aplicações de protetores solares.
BRPI0316607-4A 2002-12-12 2003-12-03 Derivados de hidroxifenil benzofenona substituídos com amino, seu uso, e preparação cosmética. BR0316607B1 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP02406093 2002-12-12
EP02406093.1 2002-12-12
CH20031113/03 2003-06-25
CH11132003 2003-06-25
EP03102297.3 2003-07-25
EP03102297 2003-07-25
PCT/EP2003/050937 WO2004052837A2 (en) 2002-12-12 2003-12-03 Amino substituted hydroxyphenyl benzophenone derivatives

Publications (2)

Publication Number Publication Date
BR0316607A true BR0316607A (pt) 2005-10-11
BR0316607B1 BR0316607B1 (pt) 2014-12-23

Family

ID=32511848

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0316607-4A BR0316607B1 (pt) 2002-12-12 2003-12-03 Derivados de hidroxifenil benzofenona substituídos com amino, seu uso, e preparação cosmética.

Country Status (11)

Country Link
US (1) US7374749B2 (pt)
EP (1) EP1569893B1 (pt)
JP (1) JP4566907B2 (pt)
KR (1) KR101057747B1 (pt)
CN (1) CN100349857C (pt)
AT (1) ATE553076T1 (pt)
AU (1) AU2003298343B2 (pt)
BR (1) BR0316607B1 (pt)
ES (1) ES2381872T3 (pt)
MX (1) MX271169B (pt)
WO (1) WO2004052837A2 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2412866A (en) * 2004-04-02 2005-10-12 Ciba Sc Holding Ag Amino-benzophenone UV filter formulations for the prevention of tanning
DE102005023634A1 (de) * 2005-05-19 2006-11-23 Beiersdorf Ag Wirkstoffkombinationen aus 2-(4'-(Diethylamino)-2'-hydoxybenzoyl)-benzoesäurehexylester und einem oder mehreren Glucosylglyceriden
GB2433439A (en) * 2005-12-21 2007-06-27 Ciba Sc Holding Ag Use of transmission dyes to protect human skin from UV radiation
EP1981895B1 (en) * 2006-02-09 2016-04-27 Basf Se Hydroxybenzophenone derivatives
DE102007005334A1 (de) 2007-02-01 2008-08-07 Beiersdorf Ag Piperazinderivate in diolhaltigen kosmetischen Zubereitungen
DE102007005333A1 (de) * 2007-02-01 2008-08-07 Beiersdorf Ag Organische Mikropigmente in kosmetischen Lichtschutzemulsionen
DE102007005336A1 (de) * 2007-02-01 2008-08-07 Beiersdorf Ag UV-Filterkombination mit Piperazinderivaten
DE102007005335A1 (de) * 2007-02-01 2008-08-07 Beiersdorf Ag Lichtschutzzubereitung mit einer Kombination von Mikropigmenten
WO2008107347A2 (en) * 2007-03-07 2008-09-12 Basf Se Use of amines and amides for the stabilization of organic micronized uv absorbers
CN101686921B (zh) * 2007-05-08 2016-10-05 巴斯夫欧洲公司 透射染料的晶型
BRPI0812845B1 (pt) * 2007-07-04 2016-07-19 Basf Se método para a preparação de uma composição compreendendo um absorvedor de uv orgânico insolúvel micronizado.
DE102007038414A1 (de) 2007-08-09 2009-02-12 Beiersdorf Ag Neue kosmetische Emulgatorkombination
KR20150132598A (ko) * 2007-11-29 2015-11-25 바스프 에스이 미세화된 유기 ｕｖ 흡수제에 대한 분쇄 조제
EP2238121A1 (de) * 2008-02-06 2010-10-13 Merck Patent GmbH Uva filter auf der basis von ascorbinsäurederivaten
US20120269750A1 (en) * 2009-11-05 2012-10-25 L'oreal Cosmetic compositions comprising an ester derived from 4-carboxy-2-pyrrolidinone and a lipophilic screening agent; use of said derivative as a solvent for a benzophenone lipophilic screening agent
US9855207B2 (en) * 2011-01-28 2018-01-02 Momentive Performance Materials Gmbh UV-photo-protecting cosmetic composition
US9203541B2 (en) 2012-09-28 2015-12-01 Intel Corporation Methods and apparatus for multiphase sampling of modulated light
CN103059168B (zh) * 2013-01-17 2014-09-17 长沙新宇高分子科技有限公司 一种二苯甲酮类光引发剂及其制备方法
US9682920B2 (en) 2013-06-27 2017-06-20 Dsm Ip Assets B.V. Method for producing 2-(4-N,N-dialkylamino-2-hydroxybenzoyl) benzoates
CN109320429A (zh) * 2013-08-12 2019-02-12 太阳化学公司 低聚氨基酮及其作为光敏引发剂的用途
JP6580788B2 (ja) 2015-12-02 2019-09-25 ノバルティス アーゲー 水溶性ｕｖ吸収化合物およびその使用
JP6546352B2 (ja) 2016-02-22 2019-07-17 ノバルティス アーゲー Ｕｖ吸収ビニルモノマーおよびその使用
PE20201164A1 (es) 2017-07-11 2020-10-28 Vertex Pharma Carboxamidas como moduladores de los canales de sodio
JP7015775B2 (ja) * 2018-11-28 2022-02-03 芳弘 二村 遺伝子修復作用を呈するポリフェノール誘導体
WO2023247598A1 (en) * 2022-06-22 2023-12-28 Skinosive Multi-photoprotective compounds and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19855649A1 (de) * 1998-12-03 2000-06-08 Basf Ag Dimere alpha-Alkyl-Styrolderivate als photostabile UV-Filter in kosmetischen und pharmazeutischen Zubereitungen
DE19917906A1 (de) * 1999-04-20 2000-10-26 Basf Ag Verwendung von aminosubstituierten Hydroxybenzophenonen als photostabile UV-Filter in kosmetischen und pharmazeutischen Zubereitungen
DE10113058A1 (de) * 2001-03-15 2002-09-19 Basf Ag Verwendung von Lichtschutzmittelkombinationen, die als wesentlichen Bestandteil 2-(4-Alkoxy-anilinomethylen)-malonsäure-dialkylester enthalten als photostabile UV-Filter in kosmetischen und pharmazeutischen Zubereitungen
FR2833164B1 (fr) * 2001-12-07 2004-07-16 Oreal Compositions cosmetiques antisolaires a base d'un melange synergique de filtres et utilisations
JP2015098471A (ja) * 2013-11-18 2015-05-28 東洋合成工業株式会社 化学種発生向上試剤

Also Published As

Publication number Publication date
AU2003298343A1 (en) 2004-06-30
BR0316607B1 (pt) 2014-12-23
US20060018846A1 (en) 2006-01-26
AU2003298343B2 (en) 2010-02-25
EP1569893A2 (en) 2005-09-07
EP1569893B1 (en) 2012-04-11
KR101057747B1 (ko) 2011-08-19
KR20050085469A (ko) 2005-08-29
US7374749B2 (en) 2008-05-20
JP4566907B2 (ja) 2010-10-20
MX271169B (es) 2009-10-23
WO2004052837A3 (en) 2004-09-10
CN100349857C (zh) 2007-11-21
JP2006509834A (ja) 2006-03-23
ATE553076T1 (de) 2012-04-15
ES2381872T3 (es) 2012-06-01
MXPA05006197A (es) 2005-08-19
CN1726184A (zh) 2006-01-25
WO2004052837A2 (en) 2004-06-24

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: C07C 229/52 , C07C 237/42 , C07C 237/32 , C07C 237/34 , C07C 237/40 , C07D 295/18 , C07D 277/66 , C07D 277/46 , C07D 313/12 , A61K 7/44

Ipc: A61K 8/42 (2006.01), A61K 8/44 (2006.01), A61K 8/4

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 23/12/2014, OBSERVADAS AS CONDICOES LEGAIS.