CL2018002411A1 - Medicamento para el tratamiento de infecciones de pie diabético - Google Patents

Medicamento para el tratamiento de infecciones de pie diabético

Info

Publication number
CL2018002411A1
CL2018002411A1 CL2018002411A CL2018002411A CL2018002411A1 CL 2018002411 A1 CL2018002411 A1 CL 2018002411A1 CL 2018002411 A CL2018002411 A CL 2018002411A CL 2018002411 A CL2018002411 A CL 2018002411A CL 2018002411 A1 CL2018002411 A1 CL 2018002411A1
Authority
CL
Chile
Prior art keywords
diabetic foot
medication
treatment
foot infections
infection site
Prior art date
Application number
CL2018002411A
Other languages
English (en)
Inventor
Grégoire Vuagniaux
Linda Kadi
Frederick Wittke
Original Assignee
Debiopharm Int Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Int Sa filed Critical Debiopharm Int Sa
Publication of CL2018002411A1 publication Critical patent/CL2018002411A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENCIÓN PROPORCIONA MEDIOS Y MÉTODOS PARA TRATAR INFECCIONES DE PIE DIABÉTICO. EN PARTICULAR, SE PROPORCIONAN COMPUESTOS FARMACOLÓGICOS QUE COMBINAN UNA ALTA ACTIVIDAD TERAPÉUTICA CONTRA BACTERIAS DE STAPHYLOCOCCUS SPP. CON UN ALTO GRADO DE PENETRACIÓN ÓSEA Y EFECTOS VASODILATADORES. ESTA COMBINACIÓN ÚNICA DE PROPIEDADES PERMITE LOGRAR ALTAS CONCENTRACIONES LOCALES DEL FÁRMACO EN EL SITIO DE INFECCIÓN INCLUSO EN PACIENTES CON PIE DIABÉTICO QUE TIENEN NORMALMENTE UNA MALA PERFUSIÓN SANGUÍNEA EN EL SITIO DE INFECCIÓN.
CL2018002411A 2016-02-26 2018-08-23 Medicamento para el tratamiento de infecciones de pie diabético CL2018002411A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16157688 2016-02-26
EP16157685 2016-02-26

Publications (1)

Publication Number Publication Date
CL2018002411A1 true CL2018002411A1 (es) 2018-12-07

Family

ID=58261637

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018002411A CL2018002411A1 (es) 2016-02-26 2018-08-23 Medicamento para el tratamiento de infecciones de pie diabético

Country Status (31)

Country Link
US (1) US10751351B2 (es)
EP (1) EP3419628B1 (es)
JP (1) JP6998881B2 (es)
KR (1) KR20180114177A (es)
CN (2) CN118416061A (es)
AU (1) AU2017223037B2 (es)
BR (2) BR112018016721A2 (es)
CA (1) CA3014541A1 (es)
CL (1) CL2018002411A1 (es)
CY (1) CY1123696T1 (es)
DK (1) DK3419628T3 (es)
EA (1) EA037121B1 (es)
ES (1) ES2842443T3 (es)
HR (1) HRP20210012T1 (es)
HU (1) HUE052140T2 (es)
IL (1) IL261116A (es)
LT (1) LT3419628T (es)
MA (1) MA43697B1 (es)
MX (1) MX2018010254A (es)
MY (1) MY189221A (es)
NZ (1) NZ745612A (es)
PH (1) PH12018501769A1 (es)
PL (1) PL3419628T3 (es)
PT (1) PT3419628T (es)
RS (1) RS61312B1 (es)
SG (1) SG11201807067YA (es)
SI (1) SI3419628T1 (es)
TN (1) TN2018000293A1 (es)
UA (1) UA123705C2 (es)
WO (1) WO2017144717A1 (es)
ZA (1) ZA201805408B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3897645A4 (en) 2018-12-21 2022-08-31 Acurx Pharmaceuticals, LLC DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF
US20220142993A1 (en) * 2019-02-14 2022-05-12 Debiopharm International S.A. Afabicin formulation, method for making the same and uses thereof
EP3982975A1 (en) 2019-06-14 2022-04-20 Debiopharm International SA Afabicin for use for treating bacterial infections involving biofilm

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BR112018016721A2 (pt) 2018-12-26
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