SG11201807067YA - Medicament for treatment of diabetic foot infections - Google Patents

Medicament for treatment of diabetic foot infections

Info

Publication number
SG11201807067YA
SG11201807067YA SG11201807067YA SG11201807067YA SG11201807067YA SG 11201807067Y A SG11201807067Y A SG 11201807067YA SG 11201807067Y A SG11201807067Y A SG 11201807067YA SG 11201807067Y A SG11201807067Y A SG 11201807067YA SG 11201807067Y A SG11201807067Y A SG 11201807067YA
Authority
SG
Singapore
Prior art keywords
international
diabetic foot
february
pct
medicament
Prior art date
Application number
SG11201807067YA
Inventor
Grégoire Vuagniaux
Linda Kadi
Frederick Wittke
Original Assignee
Debiopharm Int Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Int Sa filed Critical Debiopharm Int Sa
Publication of SG11201807067YA publication Critical patent/SG11201807067YA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD 1111101110101011111 HO 11111 011101011101110111 010111111101111011# International Bureau .. .... ..Yejd (10) International Publication Number (43) International Publication Date ..... .....!;,' WO 2017/144717 Al 31 August 2017 (31.08.2017) WIPO I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 31/675 (2006.01) A61P 31/04 (2006.01) kind of national protection available): AE, AG, AL, AM, A61K 31/4375 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, (21) International Application Number: DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, PCT/EP2017/054470 HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, (22) International Filing Date: KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, 27 February 2017 (27.02.2017) MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (25) Filing Language: English RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (26) Publication Language: English TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: 16157688.9 26 February 2016 (26.02.2016) EP (84) Designated States (unless otherwise indicated, for every 16157685.5 26 February 2016 (26.02.2016) EP kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, (71) Applicant: DEBIOPHARM INTERNATIONAL S.A. TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, [CH/CH]; Forum \"apres-demain\", Chemin Messidor 5-7, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, 1002 Lausanne (CH). DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, _ (72) Inventors: VUAGNIAUX, Gregoire; Rue Orient-Ville 8, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, 1005 Lausanne (CH). KADI, Linda; 43 Impasse des SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Rossanets, 01170 Segny (FR). WITTKE, Frederick; Zen- — _ tralstrasse 64, 6030 Ebikon (CH). Published: Agents: BACHELIN, MARTIN, HOFFMANN EITLE — with international search report (Art. 21(3)) PATENT- UND RECHTSANWALTE PARTMBB et al.; ArabellastraBe 30, 81925 Munich (DE). (74) _ = = = = = = = = = = = = = 1-1 IN Il IN 7r 7r Il IN 1-1 (54) Title: MEDICAMENT FOR TREATMENT OF DIABETIC FOOT INFECTIONS 0 N (57) : The present invention provides means and methods for treating diabetic foot infections. In particular, drug com - ea. ) pounds are provided that combine a high therapeutic activity against Staphylococcus Spp. bacteria with a high degree of bone penet- ration and vasodilatory effects. This unique combination of properties allows to accomplish high local concentrations of the drug at the site of infection even in diabetic foot patients typically having poor blood perfusion at the site of infection.
SG11201807067YA 2016-02-26 2017-02-27 Medicament for treatment of diabetic foot infections SG11201807067YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16157688 2016-02-26
EP16157685 2016-02-26
PCT/EP2017/054470 WO2017144717A1 (en) 2016-02-26 2017-02-27 Medicament for treatment of diabetic foot infections

Publications (1)

Publication Number Publication Date
SG11201807067YA true SG11201807067YA (en) 2018-09-27

Family

ID=58261637

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201807067YA SG11201807067YA (en) 2016-02-26 2017-02-27 Medicament for treatment of diabetic foot infections

Country Status (31)

Country Link
US (1) US10751351B2 (en)
EP (1) EP3419628B1 (en)
JP (1) JP6998881B2 (en)
KR (1) KR20180114177A (en)
CN (2) CN118416061A (en)
AU (1) AU2017223037B2 (en)
BR (2) BR112018016721A2 (en)
CA (1) CA3014541A1 (en)
CL (1) CL2018002411A1 (en)
CY (1) CY1123696T1 (en)
DK (1) DK3419628T3 (en)
EA (1) EA037121B1 (en)
ES (1) ES2842443T3 (en)
HR (1) HRP20210012T1 (en)
HU (1) HUE052140T2 (en)
IL (1) IL261116A (en)
LT (1) LT3419628T (en)
MA (1) MA43697B1 (en)
MX (1) MX2018010254A (en)
MY (1) MY189221A (en)
NZ (1) NZ745612A (en)
PH (1) PH12018501769A1 (en)
PL (1) PL3419628T3 (en)
PT (1) PT3419628T (en)
RS (1) RS61312B1 (en)
SG (1) SG11201807067YA (en)
SI (1) SI3419628T1 (en)
TN (1) TN2018000293A1 (en)
UA (1) UA123705C2 (en)
WO (1) WO2017144717A1 (en)
ZA (1) ZA201805408B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3897645A4 (en) 2018-12-21 2022-08-31 Acurx Pharmaceuticals, LLC Dna polymerase iiic inhibitors and use thereof
US20220142993A1 (en) * 2019-02-14 2022-05-12 Debiopharm International S.A. Afabicin formulation, method for making the same and uses thereof
EP3982975A1 (en) 2019-06-14 2022-04-20 Debiopharm International SA Afabicin for use for treating bacterial infections involving biofilm

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