CL2018001845A1 - Moduladores de la 5'-nucleotidasa, ecto y su uso - Google Patents

Moduladores de la 5'-nucleotidasa, ecto y su uso

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Publication number
CL2018001845A1
CL2018001845A1 CL2018001845A CL2018001845A CL2018001845A1 CL 2018001845 A1 CL2018001845 A1 CL 2018001845A1 CL 2018001845 A CL2018001845 A CL 2018001845A CL 2018001845 A CL2018001845 A CL 2018001845A CL 2018001845 A1 CL2018001845 A1 CL 2018001845A1
Authority
CL
Chile
Prior art keywords
ecto
compounds
nucleotidase
modulators
compositions
Prior art date
Application number
CL2018001845A
Other languages
English (en)
Inventor
Laurent Pierre Paul Debien
Juan Carlos Jaen
Jaroslaw Kalisiak
Kenneth V Lawson
Manmohan Reddy Leleti
Erick Allen Lindsey
Dillon Harding Miles
Eric Newcomb
Jay Patrick Powers
Brandon Reid Rosen
Ehesan Ul Sharif
Original Assignee
Arcus Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arcus Biosciences Inc filed Critical Arcus Biosciences Inc
Publication of CL2018001845A1 publication Critical patent/CL2018001845A1/es

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    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
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    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
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Abstract

COMPUESTOS QUE MODULAN LA CONVERSIÓN DE AMP A ADENOSINA POR LA 5’-NUCLEOTIDASA, ECTO, Y COMPOSICIONES QUE CONTIENEN LOS COMPUESTOS Y MÉTODOS PARA SINTETIZAR LOS COMPUESTOS, QUE SE DESCRIBEN EN ESTE DOCUMENTO. EL USO DE DICHOS COMPUESTOS Y COMPOSICIONES PARA EL TRATAMIENTO Y/O PREVENCIÓN DE UN DIVERSO ARREGLO DE ENFERMEDADES, DESÓRDENES Y CONDICIONES, INCLUYENDO DESÓRDENES RELACIONADOS CON CÁNCER E INMUNOLÓGICOS, QUE SE ENCUENTRAN MEDIADOS POR LA 5'-NUCLEOTIDASA, ECTO TAMBIÉN ES PROPORCIONADO.
CL2018001845A 2016-01-08 2018-07-05 Moduladores de la 5'-nucleotidasa, ecto y su uso CL2018001845A1 (es)

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US201662276564P 2016-01-08 2016-01-08
US201662324077P 2016-04-18 2016-04-18

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US11267845B2 (en) 2016-11-18 2022-03-08 Arcus Biosciences, Inc. Inhibitors of CD73-mediated immunosuppression
UA125524C2 (uk) 2016-12-08 2022-04-13 Ф. Хоффманн-Ля Рош Аг Ефірні похідні ізоксазолу як позитивні алостеричні модулятори рецептора гамк а альфа-5
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