CL2013002172A1 - Procedimiento de preparacion de un extracto de fruto de momordica charantia (melón amargo o balsamina). - Google Patents

Procedimiento de preparacion de un extracto de fruto de momordica charantia (melón amargo o balsamina).

Info

Publication number
CL2013002172A1
CL2013002172A1 CL2013002172A CL2013002172A CL2013002172A1 CL 2013002172 A1 CL2013002172 A1 CL 2013002172A1 CL 2013002172 A CL2013002172 A CL 2013002172A CL 2013002172 A CL2013002172 A CL 2013002172A CL 2013002172 A1 CL2013002172 A1 CL 2013002172A1
Authority
CL
Chile
Prior art keywords
extract
juice
momordica charantia
fruit
preparation
Prior art date
Application number
CL2013002172A
Other languages
English (en)
Inventor
Somesh Sharma
Vijay Singh Chauhan
Ashish Suthar
Original Assignee
Piramal Entpr Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46580277&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2013002172(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Piramal Entpr Ltd filed Critical Piramal Entpr Ltd
Publication of CL2013002172A1 publication Critical patent/CL2013002172A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/31Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Confectionery (AREA)

Abstract

Procedimiento para la obtención de un extracto de Momordica charantia (melón amargo o balsamina). Este procedimiento consiste en la preparación del jugo del fruto del vegetal, luego el filtrado de este jugo, luego la modificación del pH del jugo, después la neutralización alcalina del jugo, para finalizar con el secado y obtención del extracto. La solicitud contiene ejemplos que describen los detalles para la preparación del extracto de Momordica charantia. En una versión de la preparación se utiliza filtro Nutsch y secado al vacío; en otro caso se utiliza filtrado por centrifugación a alta velocidad y secado por pulverizado a alta temperatura; y en un tercer ejemplo se utiliza ácido oxálico (en vez de cítrico) e hidróxido de calcio en la etapa de neutralización.
CL2013002172A 2011-01-28 2013-07-29 Procedimiento de preparacion de un extracto de fruto de momordica charantia (melón amargo o balsamina). CL2013002172A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN246MU2011 2011-01-28

Publications (1)

Publication Number Publication Date
CL2013002172A1 true CL2013002172A1 (es) 2014-10-17

Family

ID=46580277

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013002172A CL2013002172A1 (es) 2011-01-28 2013-07-29 Procedimiento de preparacion de un extracto de fruto de momordica charantia (melón amargo o balsamina).

Country Status (19)

Country Link
US (1) US9034400B2 (es)
EP (1) EP2667884B1 (es)
JP (1) JP6018583B2 (es)
KR (1) KR20140038372A (es)
CN (1) CN103458906B (es)
BR (1) BR112013019251A2 (es)
CA (1) CA2825845C (es)
CL (1) CL2013002172A1 (es)
EC (1) ECSP13012854A (es)
ES (1) ES2621355T3 (es)
HU (1) HUE032416T2 (es)
IL (1) IL227677A (es)
MX (1) MX2013008754A (es)
MY (1) MY162398A (es)
PE (1) PE20140728A1 (es)
RU (1) RU2586770C2 (es)
UA (1) UA112174C2 (es)
WO (1) WO2012101657A1 (es)
ZA (1) ZA201305700B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2016005576A (es) * 2013-10-28 2016-12-09 Piramal Entpr Ltd Composicion herbaria, procedimiento para su preparacion y uso de la misma.
US10675319B2 (en) 2016-06-21 2020-06-09 Tci Co., Ltd. Method for regulating circadian clock, regulating diurnal preference, adjusting a biological clock, improving sleep quality and/or facilitating sleep by using momordica charantia extract
CN107468729A (zh) * 2017-08-17 2017-12-15 广西壮族自治区农业科学院农产品加工研究所 一种明日叶提取物的提取方法

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IN81887B (es) 1962-04-23 1975-08-16 M Rao
GB1435664A (en) 1974-07-08 1976-05-12 Khanna P Nag T N Jain S C Process for isolation if insulin
US5098710A (en) * 1987-06-18 1992-03-24 Yaguang Liu Production of kuguasu
CN1180545A (zh) 1996-10-24 1998-05-06 谢春生 一种复方苦瓜制剂
ATE403672T1 (de) 1997-04-01 2008-08-15 Theracos Inc Oral aktive fraktion der momordica charantia, ihre aktiven peptide und ihre verwendung bei der behandlung des diabetes
CN100413884C (zh) 1999-04-13 2008-08-27 普什帕康纳 从苦瓜中提取降血糖多肽的方法及其产物和用途
CN1098858C (zh) * 1999-07-30 2003-01-15 王力 苦瓜素的提取工艺
CN1303698A (zh) 1999-12-02 2001-07-18 潘君琦 一种苦瓜降糖胶囊及其制备工艺
CN1290575A (zh) * 1999-12-28 2001-04-11 孙进元 一种选矿用浮选剂
IN188858B (es) * 2000-08-11 2002-11-16 Ajanta Pharma Ltd
WO2003032966A1 (fr) * 2001-10-09 2003-04-24 Fancl Corporation Compositions destinees a potentialiser le glutathion
CN1418890A (zh) * 2002-09-23 2003-05-21 北海海玉农业开发有限责任公司 一种苦瓜降糖多肽的制备方法
JP2005126370A (ja) 2003-10-23 2005-05-19 Media Price Co Ltd 苦瓜を原料とするモモルデシンの回収方法
CN1290575C (zh) 2004-03-22 2006-12-20 武汉大学 含活性蛋白质的苦瓜降糖原药的制备方法
CN1858223A (zh) 2005-04-30 2006-11-08 邹远东 苦瓜多肽的制备方法和用途
JP2006314273A (ja) 2005-05-13 2006-11-24 Media Price Co Ltd 苦瓜を原料とするモモルデシンの回収方法
CN1302003C (zh) 2005-06-30 2007-02-28 天津农学院 苦瓜皂甙和苦瓜多糖的综合提取方法
CN100506238C (zh) * 2006-04-21 2009-07-01 江苏大学 一种苦瓜多糖降血糖组合物及其制备方法
JP2008120701A (ja) 2006-11-09 2008-05-29 Kuniaki Nejime 血糖値低下剤
CN101223967A (zh) * 2008-02-01 2008-07-23 广州蓝韵医药研究有限公司 苦瓜系列食品的制备方法
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CN101461514B (zh) * 2009-01-22 2011-11-30 韩金光 苦瓜提取物的制备方法
CN101485429B (zh) 2009-02-25 2013-03-27 武汉科技大学 一种可降糖的苦瓜冻干粉的制备方法
CN101637491B (zh) 2009-06-10 2011-03-30 北京一品堂医药科技有限公司 一种具有辅助降血糖、辅助降血脂功能的保健食品及其制备方法
CN101597389B (zh) 2009-07-03 2010-10-13 广东省农业科学院农业生物技术研究所 一种苦瓜皂甙和多糖混合物及其提取工艺与应用

Also Published As

Publication number Publication date
MX2013008754A (es) 2015-10-29
UA112174C2 (uk) 2016-08-10
CN103458906A (zh) 2013-12-18
CN103458906B (zh) 2016-05-25
BR112013019251A2 (pt) 2016-10-11
ZA201305700B (en) 2014-07-30
IL227677A0 (en) 2013-09-30
JP2014505071A (ja) 2014-02-27
IL227677A (en) 2016-11-30
RU2013139644A (ru) 2015-03-10
EP2667884A1 (en) 2013-12-04
JP6018583B2 (ja) 2016-11-02
US20140087012A1 (en) 2014-03-27
ECSP13012854A (es) 2013-11-29
EP2667884B1 (en) 2017-01-04
US9034400B2 (en) 2015-05-19
WO2012101657A1 (en) 2012-08-02
MY162398A (en) 2017-06-15
ES2621355T3 (es) 2017-07-03
EP2667884A4 (en) 2014-10-22
HUE032416T2 (en) 2017-09-28
CA2825845C (en) 2019-08-27
AU2012210142A1 (en) 2013-08-15
AU2012210142A8 (en) 2013-09-12
CA2825845A1 (en) 2012-08-02
PE20140728A1 (es) 2014-07-05
KR20140038372A (ko) 2014-03-28
RU2586770C2 (ru) 2016-06-10

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