CL2012000518A1 - Uso de un anticuerpo aislado o fragmento de enlace antígeno del mismo que comprende una región variable de cadena ligera y una de cadena pesada (sec nº38 y nº40) útil en el tratamiento y prevención de mieloma en un mamífero (div. sol. 3615-07). - Google Patents
Uso de un anticuerpo aislado o fragmento de enlace antígeno del mismo que comprende una región variable de cadena ligera y una de cadena pesada (sec nº38 y nº40) útil en el tratamiento y prevención de mieloma en un mamífero (div. sol. 3615-07).Info
- Publication number
- CL2012000518A1 CL2012000518A1 CL2012000518A CL2012000518A CL2012000518A1 CL 2012000518 A1 CL2012000518 A1 CL 2012000518A1 CL 2012000518 A CL2012000518 A CL 2012000518A CL 2012000518 A CL2012000518 A CL 2012000518A CL 2012000518 A1 CL2012000518 A1 CL 2012000518A1
- Authority
- CL
- Chile
- Prior art keywords
- div
- myeloma
- sol
- mammal
- antigen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Uso de un anticuerpo aislado o fragmento de enlace antígeno del mismo que comprende una región variable de cadena ligera y una de cadena pesada (SEC Nº38 y Nº40) útil en el tratamiento y prevención de mieloma en un mamífero (Div. Sol. 3615-07).
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87458906P | 2006-12-13 | 2006-12-13 | |
US87093706P | 2006-12-20 | 2006-12-20 | |
US94601107P | 2007-06-25 | 2007-06-25 | |
US97927407P | 2007-10-11 | 2007-10-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2012000518A1 true CL2012000518A1 (es) | 2012-10-05 |
Family
ID=39400630
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2012000518A CL2012000518A1 (es) | 2006-12-13 | 2012-02-28 | Uso de un anticuerpo aislado o fragmento de enlace antígeno del mismo que comprende una región variable de cadena ligera y una de cadena pesada (sec nº38 y nº40) útil en el tratamiento y prevención de mieloma en un mamífero (div. sol. 3615-07). |
CL2012000519A CL2012000519A1 (es) | 2006-12-13 | 2012-02-28 | Uso de un anticuerpo aislado o fragmento de enlace antígeno del mismo que comprende una región variable de cadena ligera y una de cadena pesada (sec nº38 y nº40) útil en el tratamiento y prevención de carcinoma de células escamosas en un mamífero (div. sol. 3615-07). |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2012000519A CL2012000519A1 (es) | 2006-12-13 | 2012-02-28 | Uso de un anticuerpo aislado o fragmento de enlace antígeno del mismo que comprende una región variable de cadena ligera y una de cadena pesada (sec nº38 y nº40) útil en el tratamiento y prevención de carcinoma de células escamosas en un mamífero (div. sol. 3615-07). |
Country Status (12)
Country | Link |
---|---|
US (1) | US20110262525A1 (es) |
EP (1) | EP2104501B1 (es) |
JP (2) | JP2010513278A (es) |
CN (1) | CN102123712B (es) |
AU (1) | AU2007334456A1 (es) |
CA (1) | CA2672828A1 (es) |
CL (2) | CL2012000518A1 (es) |
MX (1) | MX2009006466A (es) |
NO (1) | NO20092637L (es) |
NZ (1) | NZ578329A (es) |
TW (1) | TW200840583A (es) |
WO (1) | WO2008076278A2 (es) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101313702B1 (ko) | 2005-02-03 | 2013-10-04 | 와이어쓰 | 제피티니브 및/또는 에를로티니브 내성암 치료용 약제학적 조성물 |
TW200803892A (en) | 2005-11-04 | 2008-01-16 | Wyeth Corp | Antineoplastic combinations with MTOR inhibitor, herceptin, and/or HKI-272 |
AU2008223541B2 (en) * | 2007-03-02 | 2012-04-05 | Amgen Inc. | Methods and compositions for treating tumor diseases |
AU2012203443B2 (en) * | 2007-03-02 | 2014-03-06 | Amgen Inc. | Methods and compositions for treating tumor diseases |
US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
JP2011505873A (ja) * | 2007-12-18 | 2011-03-03 | シェーリング コーポレイション | 抗igf1r療法に対する感受性のバイオマーカー |
PE20091714A1 (es) * | 2008-04-11 | 2009-11-15 | Galaxy Biotech Llc | Combinacion del inhibidor hgf y el agonista pten |
PT2310011E (pt) | 2008-06-17 | 2013-10-07 | Wyeth Llc | Combinações antineoplásicas contendo hki-272 e vinorelbina |
KR20140069340A (ko) | 2008-08-04 | 2014-06-09 | 와이어쓰 엘엘씨 | 4-아닐리노-3-사이아노퀴놀린과 카페시타빈의 항신생물성 조합물 |
CA2756870A1 (en) | 2009-03-31 | 2010-10-07 | Arqule, Inc. | Substituted indolo-pyridinone compounds |
HUE061640T2 (hu) | 2009-04-06 | 2023-07-28 | Wyeth Llc | Gyógykezelési rendszer mellrákhoz neratinib alkalmazásával |
JP2013512215A (ja) * | 2009-11-25 | 2013-04-11 | ノバルティス アーゲー | 二環式ヘテロアリールのベンゼン縮合6員酸素含有ヘテロ環誘導体 |
GB201007286D0 (en) | 2010-04-30 | 2010-06-16 | Astex Therapeutics Ltd | New compounds |
GB201020179D0 (en) | 2010-11-29 | 2011-01-12 | Astex Therapeutics Ltd | New compounds |
WO2012088266A2 (en) | 2010-12-22 | 2012-06-28 | Incyte Corporation | Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3 |
AU2012253571A1 (en) | 2011-05-09 | 2014-01-09 | Mayo Foundation For Medical Education And Research | Cancer treatments |
GB201118656D0 (en) | 2011-10-28 | 2011-12-07 | Astex Therapeutics Ltd | New compounds |
GB201118675D0 (en) | 2011-10-28 | 2011-12-14 | Astex Therapeutics Ltd | New compounds |
GB201118654D0 (en) | 2011-10-28 | 2011-12-07 | Astex Therapeutics Ltd | New compounds |
GB201118652D0 (en) | 2011-10-28 | 2011-12-07 | Astex Therapeutics Ltd | New compounds |
WO2013152252A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
GB201209613D0 (en) | 2012-05-30 | 2012-07-11 | Astex Therapeutics Ltd | New compounds |
GB201209609D0 (en) | 2012-05-30 | 2012-07-11 | Astex Therapeutics Ltd | New compounds |
RS55908B1 (sr) | 2012-06-13 | 2017-09-29 | Incyte Holdings Corp | Substituisana triciklična jedinjenja kao inhibitori fgfr |
WO2014026125A1 (en) | 2012-08-10 | 2014-02-13 | Incyte Corporation | Pyrazine derivatives as fgfr inhibitors |
EP3967306A1 (en) | 2012-10-01 | 2022-03-16 | Mayo Foundation for Medical Education and Research | Cancer treatments |
US10015980B2 (en) * | 2012-10-22 | 2018-07-10 | University Of Southern California | Methods and formulations promoting tissue/organ regeneration, longevity and healthspan |
US9266892B2 (en) | 2012-12-19 | 2016-02-23 | Incyte Holdings Corporation | Fused pyrazoles as FGFR inhibitors |
MX367878B (es) | 2013-04-19 | 2019-09-10 | Incyte Holdings Corp | Heterociclos bicíclicos como inhibidores de los receptores del factor de crecimiento de fibroblastos (fgfr). |
GB201307577D0 (en) | 2013-04-26 | 2013-06-12 | Astex Therapeutics Ltd | New compounds |
CN106458999B (zh) | 2014-03-26 | 2019-12-03 | 阿斯特克斯治疗有限公司 | 组合 |
JO3512B1 (ar) | 2014-03-26 | 2020-07-05 | Astex Therapeutics Ltd | مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز |
BR112016022062B1 (pt) * | 2014-03-26 | 2023-04-11 | Astex Therapeutics Limited | Combinação, composição farmacêutica, uso de uma combinação ou de uma composição farmacêutica, e, produto farmacêutico |
KR20170020371A (ko) * | 2014-06-16 | 2017-02-22 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 골수종의 치료 |
US9446148B2 (en) | 2014-10-06 | 2016-09-20 | Mayo Foundation For Medical Education And Research | Carrier-antibody compositions and methods of making and using the same |
CN106999517A (zh) * | 2014-10-07 | 2017-08-01 | 免疫医疗公司 | 抗体‑药物缀合物的新辅助剂用途 |
US10851105B2 (en) | 2014-10-22 | 2020-12-01 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
CN104447777B (zh) * | 2014-11-26 | 2016-09-14 | 浙江大学 | 一种辣椒碱-喜树碱类抗癌药物偶联物及其制备方法和应用 |
CN104478890B (zh) * | 2014-11-26 | 2016-09-14 | 浙江大学 | 一种全反式维甲酸-喜树碱类抗癌药物偶联物及其制备方法和应用 |
JOP20200201A1 (ar) | 2015-02-10 | 2017-06-16 | Astex Therapeutics Ltd | تركيبات صيدلانية تشتمل على n-(3.5- ثنائي ميثوكسي فينيل)-n'-(1-ميثيل إيثيل)-n-[3-(ميثيل-1h-بيرازول-4-يل) كينوكسالين-6-يل]إيثان-1.2-ثنائي الأمين |
ES2751669T3 (es) | 2015-02-20 | 2020-04-01 | Incyte Corp | Heterociclos bicíclicos como inhibidores FGFR |
MA41551A (fr) | 2015-02-20 | 2017-12-26 | Incyte Corp | Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4 |
WO2016134294A1 (en) | 2015-02-20 | 2016-08-25 | Incyte Corporation | Bicyclic heterocycles as fgfr4 inhibitors |
US10478494B2 (en) | 2015-04-03 | 2019-11-19 | Astex Therapeutics Ltd | FGFR/PD-1 combination therapy for the treatment of cancer |
TW201707725A (zh) | 2015-08-18 | 2017-03-01 | 美國馬友醫藥教育研究基金會 | 載體-抗體組合物及其製造及使用方法 |
US11155555B2 (en) | 2015-09-23 | 2021-10-26 | Janssen Pharmaceutica Nv | Compounds |
RU2747644C2 (ru) | 2015-09-23 | 2021-05-11 | Янссен Фармацевтика Нв | Бигетероарил-замещенные 1,4-бензодиазепины и пути их применения для лечения рака |
AU2016331819B2 (en) * | 2015-09-30 | 2023-08-24 | Janssen Biotech, Inc. | Agonistic antibodies specifically binding human CD40 and methods of use |
TW201713360A (en) | 2015-10-06 | 2017-04-16 | Mayo Foundation | Methods of treating cancer using compositions of antibodies and carrier proteins |
WO2017120501A1 (en) | 2016-01-07 | 2017-07-13 | Mayo Foundation For Medical Education And Research | Methods of treating cancer with interferon |
CA3014531A1 (en) | 2016-02-12 | 2017-08-17 | Mayo Foundation For Medical Education And Research | Hematologic cancer treatments |
AU2017238119A1 (en) | 2016-03-21 | 2018-10-11 | Mayo Foundation For Medical Education And Research | Methods for reducing toxicity of a chemotherapeutic drug |
WO2017165439A1 (en) | 2016-03-21 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods for improving the therapeutic index for a chemotherapeutic drug |
US10105389B1 (en) | 2016-04-01 | 2018-10-23 | Howard Alliger | Method and compositions for treating cancerous tumors |
US10618969B2 (en) | 2016-04-06 | 2020-04-14 | Mayo Foundation For Medical Education And Research | Carrier-binding agent compositions and methods of making and using the same |
CN107569493B (zh) * | 2016-07-04 | 2020-03-06 | 北京市神经外科研究所 | 氟维司群在制备治疗无功能垂体腺瘤的药物中的用途 |
EP3506950A1 (en) | 2016-09-01 | 2019-07-10 | Mayo Foundation for Medical Education and Research | Methods and compositions for targeting t-cell cancers |
EP4177271A1 (en) | 2016-09-01 | 2023-05-10 | Mayo Foundation for Medical Education and Research | Carrier-pd-l1 binding agent compositions for treating cancers |
JP2019526587A (ja) | 2016-09-06 | 2019-09-19 | マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチMayo Foundation For Medical Education And Research | Pd−l1を発現する癌を処置する方法 |
WO2018048815A1 (en) | 2016-09-06 | 2018-03-15 | Nantibodyfc, Llc | Methods of treating triple-negative breast cancer using compositions of antibodies and carrier proteins |
MX2019002564A (es) | 2016-09-06 | 2019-09-18 | Mayo Found Medical Education & Res | Composiciones de agente de unión de albúmina-paclitaxel y métodos de uso y elaboración de las mismas. |
JP7032406B2 (ja) * | 2016-09-13 | 2022-03-08 | ラスナ・リサーチ・インコーポレイテッド | ダクチノマイシン組成物並びに骨髄異形成症候群及び急性骨髄性白血病の治療方法 |
EP3630195A4 (en) * | 2017-05-21 | 2021-03-24 | IGF Oncology, LLC | INSULIN-LIKE GROWTH FACTOR CONJUGATE - CHEMOTHERAPEUTIC PRODUCT FOR THE TREATMENT OF MYELODYSPLASIC SYNDROME |
AR111960A1 (es) | 2017-05-26 | 2019-09-04 | Incyte Corp | Formas cristalinas de un inhibidor de fgfr y procesos para su preparación |
AU2019262195B2 (en) | 2018-05-04 | 2024-09-12 | Incyte Corporation | Solid forms of an FGFR inhibitor and processes for preparing the same |
MA52493A (fr) | 2018-05-04 | 2021-03-10 | Incyte Corp | Sels d'un inhibiteur de fgfr |
US11628162B2 (en) | 2019-03-08 | 2023-04-18 | Incyte Corporation | Methods of treating cancer with an FGFR inhibitor |
WO2021007269A1 (en) | 2019-07-09 | 2021-01-14 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
TW202128173A (zh) * | 2019-10-09 | 2021-08-01 | 美商G1治療公司 | 失調之纖維母細胞生長因子受體訊息傳遞的癌症之標靶性治療 |
CN115835908A (zh) | 2019-10-14 | 2023-03-21 | 因赛特公司 | 作为fgfr抑制剂的双环杂环 |
WO2021076728A1 (en) | 2019-10-16 | 2021-04-22 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
JP2023505258A (ja) | 2019-12-04 | 2023-02-08 | インサイト・コーポレイション | Fgfr阻害剤としての三環式複素環 |
US11407750B2 (en) | 2019-12-04 | 2022-08-09 | Incyte Corporation | Derivatives of an FGFR inhibitor |
WO2021146424A1 (en) | 2020-01-15 | 2021-07-22 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
CN113512116B (zh) * | 2020-04-10 | 2022-09-20 | 苏州普乐康医药科技有限公司 | 一种抗igf-1r抗体及其应用 |
JP2023533060A (ja) * | 2020-07-08 | 2023-08-01 | デイトン・セラピューティクス・アクチェンゲゼルシャフト | リンパ系組織の悪性腫瘍 |
CN112125916A (zh) * | 2020-09-28 | 2020-12-25 | 杭州仁者生物科技有限公司 | 胰岛素样生长因子-1受体的新型小分子抑制剂及其用途 |
CA3215903A1 (en) | 2021-04-12 | 2022-10-20 | Incyte Corporation | Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent |
CA3220274A1 (en) | 2021-06-09 | 2022-12-15 | Incyte Corporation | Tricyclic heterocycles as fgfr inhibitors |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986005807A1 (en) | 1985-04-01 | 1986-10-09 | Celltech Limited | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
US6300129B1 (en) * | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
GB9800569D0 (en) | 1998-01-12 | 1998-03-11 | Glaxo Group Ltd | Heterocyclic compounds |
DZ3494A1 (fr) | 2001-01-05 | 2002-07-11 | Pfizer | Anticorps anti-recepteur du facteur de croissance i analogue a l'insuline |
TWI238824B (en) * | 2001-05-14 | 2005-09-01 | Novartis Ag | 4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives |
FR2834900B1 (fr) | 2002-01-18 | 2005-07-01 | Pf Medicament | Nouvelles compositions a activite anti-igf-ir et anti-egfr et leurs applications |
EP1806364B1 (fr) * | 2002-01-18 | 2013-07-31 | Pierre Fabre Medicament | Nouveaux anticorps anti-igf-ir et leurs applications |
FR2834991B1 (fr) | 2002-01-18 | 2004-12-31 | Pf Medicament | Nouveaux anticorps anti-igf-ir et leurs applications |
FR2834990A1 (fr) | 2002-01-18 | 2003-07-25 | Pf Medicament | Nouveaux anticorps anti-igf-ir et leurs applications |
US20050113577A1 (en) | 2002-04-16 | 2005-05-26 | Karki Shyam B. | Solid forms of slats with tyrosine kinase activity |
NZ571508A (en) * | 2002-05-24 | 2010-05-28 | Schering Corp | Neutralizing human anti-IGFR antibody |
US7538195B2 (en) | 2002-06-14 | 2009-05-26 | Immunogen Inc. | Anti-IGF-I receptor antibody |
CA2514231A1 (en) | 2003-02-13 | 2004-08-26 | Pfizer Products Inc. | Uses of anti-insulin-like growth factor i receptor antibodies |
WO2004083248A1 (en) | 2003-03-14 | 2004-09-30 | Pharmacia Corporation | Antibodies to igf-i receptor for the treatment of cancers |
JP4473257B2 (ja) | 2003-04-02 | 2010-06-02 | エフ.ホフマン−ラ ロシュ アーゲー | インスリン様成長因子i受容体に対する抗体及びその使用 |
JP2007535895A (ja) | 2003-05-01 | 2007-12-13 | イムクローン システムズ インコーポレイティド | ヒトインシュリン様成長因子−1受容体に対する完全ヒト抗体 |
ES2368741T3 (es) * | 2004-02-25 | 2011-11-21 | Dana-Farber Cancer Institute, Inc. | Inhibidores del receptor 1 del factor de crecimiento de tipo insulina para inhibir el crecimiento de células tumorales. |
US7811562B2 (en) * | 2004-12-03 | 2010-10-12 | Schering Corporation | Biomarkers for pre-selection of patients for anti-IGF1R therapy |
WO2006113483A2 (en) * | 2005-04-15 | 2006-10-26 | Schering Corporation | Methods and compositions for treating or preventing cancer |
-
2007
- 2007-12-11 AU AU2007334456A patent/AU2007334456A1/en not_active Abandoned
- 2007-12-11 US US12/518,409 patent/US20110262525A1/en not_active Abandoned
- 2007-12-11 WO PCT/US2007/025398 patent/WO2008076278A2/en active Application Filing
- 2007-12-11 EP EP07862806.2A patent/EP2104501B1/en active Active
- 2007-12-11 MX MX2009006466A patent/MX2009006466A/es not_active Application Discontinuation
- 2007-12-11 JP JP2009541358A patent/JP2010513278A/ja not_active Withdrawn
- 2007-12-11 CA CA002672828A patent/CA2672828A1/en not_active Abandoned
- 2007-12-11 NZ NZ578329A patent/NZ578329A/en not_active IP Right Cessation
- 2007-12-11 CN CN200780051289.8A patent/CN102123712B/zh not_active Expired - Fee Related
- 2007-12-12 TW TW096147348A patent/TW200840583A/zh unknown
-
2009
- 2009-07-10 NO NO20092637A patent/NO20092637L/no not_active Application Discontinuation
-
2012
- 2012-02-28 CL CL2012000518A patent/CL2012000518A1/es unknown
- 2012-02-28 CL CL2012000519A patent/CL2012000519A1/es unknown
- 2012-07-12 JP JP2012156460A patent/JP2012193204A/ja active Pending
Also Published As
Publication number | Publication date |
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EP2104501A2 (en) | 2009-09-30 |
CN102123712B (zh) | 2014-03-19 |
JP2012193204A (ja) | 2012-10-11 |
WO2008076278A4 (en) | 2009-06-25 |
CL2012000519A1 (es) | 2012-10-05 |
WO2008076278A3 (en) | 2009-05-07 |
CN102123712A (zh) | 2011-07-13 |
JP2010513278A (ja) | 2010-04-30 |
CA2672828A1 (en) | 2008-06-26 |
NZ578329A (en) | 2012-05-25 |
WO2008076278A2 (en) | 2008-06-26 |
TW200840583A (en) | 2008-10-16 |
AU2007334456A1 (en) | 2008-06-26 |
MX2009006466A (es) | 2009-06-26 |
NO20092637L (no) | 2009-09-11 |
WO2008076278A8 (en) | 2013-03-28 |
US20110262525A1 (en) | 2011-10-27 |
EP2104501B1 (en) | 2014-03-12 |
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