CL2009001490A1 - Sistema de suministro intrauterino que comprende un progestageno o una droga con actividad progestagenica y una sustancia terapeuticamente activa seleccionada de naproxeno, indometacina, ibuprofeno, acido mefenamico o flurbiprofeno, con la capacidad de evitar o suprimir el sangrado anormal y/o irregular. - Google Patents

Sistema de suministro intrauterino que comprende un progestageno o una droga con actividad progestagenica y una sustancia terapeuticamente activa seleccionada de naproxeno, indometacina, ibuprofeno, acido mefenamico o flurbiprofeno, con la capacidad de evitar o suprimir el sangrado anormal y/o irregular.

Info

Publication number
CL2009001490A1
CL2009001490A1 CL2009001490A CL2009001490A CL2009001490A1 CL 2009001490 A1 CL2009001490 A1 CL 2009001490A1 CL 2009001490 A CL2009001490 A CL 2009001490A CL 2009001490 A CL2009001490 A CL 2009001490A CL 2009001490 A1 CL2009001490 A1 CL 2009001490A1
Authority
CL
Chile
Prior art keywords
active substance
therapeutically active
progestagen
drug
ability
Prior art date
Application number
CL2009001490A
Other languages
English (en)
Inventor
Jukarainen Harri
Duesterberg Bernd
Ahola Manja
Pihlaja Jyrki
Kleemola Satu
Parkatti Tero
Bernhard Lindenthal
Ulrike Fuhrmann
Tuula Valo
Lyytikäinen Heikki
Ina Gröticke
Original Assignee
Bayer Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40020198&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2009001490(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Oy filed Critical Bayer Oy
Publication of CL2009001490A1 publication Critical patent/CL2009001490A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Communication Control (AREA)

Abstract

SISTEMA DE SUMINISTRO INTRAUTERINO PARA LA LIBERACIÓN CONTROLADA DE PROGESTÁGENO —O UNA DROGA QUE TIENE UNA ACTIVIDAD PROGESTAGÉNICA— DURANTE UN PERÍODO PROLONGADO Y A UN NIVEL REQUERIDO PARA LA ANTICONCEPCIÓN Y PARA REDUCIR PROBLEMAS MENSTRUALES Y PARA INDUCIR AMENORREA Y EN EL CUAL, EL SISTEMA DE SUMINISTRO INTRAUTERINO COMPRENDE UNA ESTRUCTURA DE UN CUERPO Y AL MENOS UN DEPÓSITO QUE COMPRENDE UN NÚCLEO Y - OPCIONALMENTE— UNA MEMBRANA QUE REVISTE EL NÚCLEO, EL NÚCLEO Y LA MEMBRANA CONSISTEN ESENCIALMENTE EN UNA COMPOSICIÓN POLIMÉRICA IGUAL O DIFERENTE, DONDE DICHO SISTEMA DE SUMINISTRO INTRAUTERINO ADICIONALMENTE COMPRENDE AL MENOS UNA SUSTANCIA TERAPÉUTICAMENTE ACTIVA CON LA CAPACIDAD DE EVITAR O SUPRIMIR EL SANGRADO ENDOMETRIAL ANORMAL Y/O IRREGULAR, DONDE LA SUSTANCIA TERAPÉUTICAMENTE ACTIVA SE SELECCIONA DE NAPROXENO, INDOMETACINA, IBUPROFENO, ÁCIDO MEFENÁMICO O FLURBIPROFENO.
CL2009001490A 2008-07-03 2009-06-26 Sistema de suministro intrauterino que comprende un progestageno o una droga con actividad progestagenica y una sustancia terapeuticamente activa seleccionada de naproxeno, indometacina, ibuprofeno, acido mefenamico o flurbiprofeno, con la capacidad de evitar o suprimir el sangrado anormal y/o irregular. CL2009001490A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08397516A EP2140860A1 (en) 2008-07-03 2008-07-03 An improved method of contraception

Publications (1)

Publication Number Publication Date
CL2009001490A1 true CL2009001490A1 (es) 2010-08-06

Family

ID=40020198

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009001490A CL2009001490A1 (es) 2008-07-03 2009-06-26 Sistema de suministro intrauterino que comprende un progestageno o una droga con actividad progestagenica y una sustancia terapeuticamente activa seleccionada de naproxeno, indometacina, ibuprofeno, acido mefenamico o flurbiprofeno, con la capacidad de evitar o suprimir el sangrado anormal y/o irregular.

Country Status (22)

Country Link
US (3) US20110146693A1 (es)
EP (3) EP2140860A1 (es)
JP (3) JP2011526609A (es)
KR (2) KR20110026516A (es)
CN (2) CN102088954A (es)
AR (1) AR072544A1 (es)
CA (1) CA2730040A1 (es)
CL (1) CL2009001490A1 (es)
CY (1) CY1120878T1 (es)
DK (1) DK2905014T3 (es)
ES (1) ES2673154T3 (es)
HR (1) HRP20180869T1 (es)
HU (1) HUE037520T2 (es)
LT (1) LT2905014T (es)
PE (1) PE20100057A1 (es)
PL (1) PL2905014T3 (es)
PT (1) PT2905014T (es)
SI (1) SI2905014T1 (es)
TR (1) TR201807996T4 (es)
TW (2) TW201002288A (es)
UY (1) UY31957A (es)
WO (1) WO2010000943A1 (es)

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Also Published As

Publication number Publication date
UY31957A (es) 2010-01-29
KR20150136143A (ko) 2015-12-04
CY1120878T1 (el) 2019-12-11
US20180263899A1 (en) 2018-09-20
KR20110026516A (ko) 2011-03-15
LT2905014T (lt) 2018-07-10
US20110146693A1 (en) 2011-06-23
JP2014129412A (ja) 2014-07-10
HUE037520T2 (hu) 2018-09-28
HRP20180869T1 (hr) 2018-08-24
WO2010000943A1 (en) 2010-01-07
TWI602556B (zh) 2017-10-21
ES2673154T3 (es) 2018-06-20
TR201807996T4 (tr) 2018-06-21
JP6008893B2 (ja) 2016-10-19
DK2905014T3 (en) 2018-06-25
EP2140860A1 (en) 2010-01-06
PT2905014T (pt) 2018-06-22
SI2905014T1 (en) 2018-08-31
TW201002288A (en) 2010-01-16
US20140127280A1 (en) 2014-05-08
JP2016166245A (ja) 2016-09-15
KR101659530B1 (ko) 2016-09-23
CN102088954A (zh) 2011-06-08
EP2905014A1 (en) 2015-08-12
EP2313084A1 (en) 2011-04-27
PE20100057A1 (es) 2010-02-25
PL2905014T3 (pl) 2018-10-31
EP2313084A4 (en) 2014-03-05
EP2905014B1 (en) 2018-04-25
US9999592B2 (en) 2018-06-19
US10532025B2 (en) 2020-01-14
CA2730040A1 (en) 2010-01-07
AR072544A1 (es) 2010-09-08
JP2011526609A (ja) 2011-10-13
CN103976816A (zh) 2014-08-13
TW201601699A (zh) 2016-01-16

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