MX2008011823A - Forma de dosificacion solida que contiene un agente activo de sabor encubierto. - Google Patents

Forma de dosificacion solida que contiene un agente activo de sabor encubierto.

Info

Publication number
MX2008011823A
MX2008011823A MX2008011823A MX2008011823A MX2008011823A MX 2008011823 A MX2008011823 A MX 2008011823A MX 2008011823 A MX2008011823 A MX 2008011823A MX 2008011823 A MX2008011823 A MX 2008011823A MX 2008011823 A MX2008011823 A MX 2008011823A
Authority
MX
Mexico
Prior art keywords
solid dosage
active agent
dosage form
taste masked
form containing
Prior art date
Application number
MX2008011823A
Other languages
English (en)
Inventor
Alexander Mark Schobel
Shyam Sundar Kumar Sarma Vangala
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2008011823A publication Critical patent/MX2008011823A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se proporciona una forma de dosificación sólida que contiene un agente activo de sabor encubierto. La forma de dosificación sólida puede ser proporcionada como una película soluble en agua que es desintegrable en la cavidad oral para liberar y distribuir el agente activo de sabor encubierto. La película desintegrable incluye al menos un polímero soluble en agua y un ketoprofeno activo de sabor encubierto. También se proporcionan métodos para preparar la forma de dosificación sólida y para usar la forma de dosificación sólida para administrar una dosificación efectiva de un agente activo, tal como ketoprofeno, en la cavidad oral para absorción.
MX2008011823A 2006-03-16 2007-03-15 Forma de dosificacion solida que contiene un agente activo de sabor encubierto. MX2008011823A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78318906P 2006-03-16 2006-03-16
PCT/US2007/006452 WO2007109057A2 (en) 2006-03-16 2007-03-15 Solid dosage form containing a taste masked active agent

Publications (1)

Publication Number Publication Date
MX2008011823A true MX2008011823A (es) 2008-10-31

Family

ID=38372464

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008011823A MX2008011823A (es) 2006-03-16 2007-03-15 Forma de dosificacion solida que contiene un agente activo de sabor encubierto.

Country Status (15)

Country Link
US (2) US8986735B2 (es)
EP (1) EP1998762B1 (es)
JP (1) JP5242543B2 (es)
CN (1) CN101404990B (es)
AT (1) ATE486593T1 (es)
AU (1) AU2007227614B2 (es)
BR (1) BRPI0709382A2 (es)
CA (1) CA2643944C (es)
DE (1) DE602007010254D1 (es)
ES (1) ES2355306T3 (es)
MX (1) MX2008011823A (es)
PL (1) PL1998762T3 (es)
PT (1) PT1998762E (es)
RU (1) RU2437657C2 (es)
WO (1) WO2007109057A2 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE486593T1 (de) * 2006-03-16 2010-11-15 Novartis Ag Feste dosierungsform mit einem wirkstoff mit unterdrücktem geschmack
UY32836A (es) 2009-08-12 2011-03-31 Bayer Schering Pharma Ag Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato
KR20120056824A (ko) 2009-08-19 2012-06-04 바이엘 파마 악티엔게젤샤프트 소아과 용도를 위한 약물 전달 시스템 （웨이퍼）
JP6050564B2 (ja) * 2010-03-11 2016-12-21 テイカ製薬株式会社 フィルム状製剤
JP2012031164A (ja) * 2010-07-06 2012-02-16 Teika Seiyaku Kk フィルム状製剤
JP5853460B2 (ja) * 2010-07-30 2016-02-09 大正製薬株式会社 内服液剤
ES2556985T3 (es) 2011-01-11 2016-01-21 Capsugel Belgium Nv Nuevas cápsulas duras que comprenden pululano
EP2717852B1 (en) 2011-06-08 2019-05-08 LTS LOHMANN Therapie-Systeme AG Edible oral strip or wafer dosage form containing ion exchange resin for taste masking
WO2013129889A2 (ko) 2012-02-28 2013-09-06 주식회사 서울제약 실데나필을 유효성분으로 함유하며 고미가 은폐된 고함량 속용필름
KR101328350B1 (ko) 2012-02-28 2013-11-11 주식회사 서울제약 실데나필 또는 이의 약제학적으로 허용되는 염을 유효성분으로 함유하는 고미가 은폐된 약제학적 조성물
JP2013231011A (ja) * 2012-05-01 2013-11-14 Sawai Pharmaceutical Co Ltd アトルバスタチン含有医薬組成物およびそれを用いた口腔内崩壊錠
AU2015280262B2 (en) * 2014-06-24 2020-08-13 Taho Pharmaceuticals Ltd. Fast acting orally disintegrating film
EA033662B1 (ru) * 2014-07-17 2019-11-14 Hexal Ag Перорально распадающаяся пленка (варианты), ее применение и пленкообразующая суспензия
CN104257637A (zh) * 2014-09-26 2015-01-07 天津市聚星康华医药科技有限公司 一种酮洛芬口腔速溶膜及其制备方法
WO2018129079A1 (en) * 2017-01-03 2018-07-12 Thermolife International, Llc Method of isolating theacrine and composition comprising theacrine
US20190336453A1 (en) * 2017-01-04 2019-11-07 BonAyu Lifesciences Private Limited Oral dispersible film composition
JP2020516653A (ja) 2017-04-14 2020-06-11 カプスゲル・ベルギウム・ナムローゼ・フェンノートシャップＣａｐｓｕｇｅｌ Ｂｅｌｇｉｕｍ ＮＶ プルランカプセル
AU2018253392B2 (en) 2017-04-14 2023-11-02 Capsugel Belgium Nv Process for making pullulan
CN108113962B (zh) * 2018-02-23 2021-06-25 成都中医药大学 一种降低含有多酚的中药口服制剂涩味的方法

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4145440A (en) * 1977-08-18 1979-03-20 The Upjohn Company Liquid suspension of an aluminum salt of ibuprofen
US4361580A (en) * 1980-06-20 1982-11-30 The Upjohn Manufacturing Company Aluminum ibuprofen pharmaceutical suspensions
GB8813682D0 (en) * 1988-06-09 1988-07-13 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
US5416181A (en) * 1989-02-10 1995-05-16 Penford Products Company Reinforced films made from water soluble polymers
CA2021548A1 (en) * 1989-09-01 1991-03-02 Ronald Nash Duvall Effervescent cold or sinus allergy medicine composition having reduced sodium content
US5262179A (en) * 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
DE4018247A1 (de) * 1990-06-07 1991-12-12 Lohmann Therapie Syst Lts Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen
US5024997A (en) * 1990-06-22 1991-06-18 American Home Products Corporation Palatable ibuprofen solutions
JPH0541602A (ja) 1991-08-06 1993-02-19 Fujitsu General Ltd 円偏波及び直線偏波共用一次放射器
GB9207990D0 (en) * 1992-04-10 1992-05-27 Smithkline Beecham Plc Pharmaceutical composition
TW271400B (es) * 1992-07-30 1996-03-01 Pfizer
GB9316580D0 (en) * 1993-08-10 1993-09-29 Smithkline Beecham Plc Pharmaceutical composition
GB9318880D0 (en) * 1993-09-11 1993-10-27 Smithkline Beecham Plc Pharmaceutical composition
IT1277741B1 (it) * 1995-12-28 1997-11-12 Dompe Spa Composizioni farmaceutiche parenterali contenenti sali di alchilammonio di acidi 2-arilpropionici
AUPN969796A0 (en) * 1996-05-07 1996-05-30 F.H. Faulding & Co. Limited Taste masked liquid suspensions
US5800832A (en) * 1996-10-18 1998-09-01 Virotex Corporation Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces
DE19646392A1 (de) * 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
ES2274625T3 (es) * 1998-05-18 2007-05-16 Takeda Pharmaceutical Company Limited Comprimidos desintegrables en la boca que comprenden un bencimidazol.
US20030206942A1 (en) * 1998-09-25 2003-11-06 Neema Kulkarni Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
AU3574500A (en) * 1999-03-25 2000-10-16 Yuhan Corporation Rapidly disintegrable tablet for oral administration
US6090401A (en) * 1999-03-31 2000-07-18 Mcneil-Ppc, Inc. Stable foam composition
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
US6995190B2 (en) * 2001-03-09 2006-02-07 Veterinary Solutions Method and treatment with ketoprofen solution
US6656493B2 (en) * 2001-07-30 2003-12-02 Wm. Wrigley Jr. Company Edible film formulations containing maltodextrin
US6419903B1 (en) * 2001-08-20 2002-07-16 Colgate Palmolive Company Breath freshening film
DE10207394B4 (de) * 2002-02-21 2007-03-29 Lts Lohmann Therapie-Systeme Ag Geschmacksmaskierte oblatenförmige Arzneizubereitung
US20040043134A1 (en) * 2002-08-27 2004-03-04 Corriveau Christine Leclair Rolled edible thin film products and methods of making same
US7090859B2 (en) * 2002-12-13 2006-08-15 Ronald Thomas Haas Ketoprofen compositions and methods of making them
US20040208931A1 (en) * 2002-12-30 2004-10-21 Friend David R Fast dissolving films for oral administration of drugs
WO2005004989A2 (en) * 2003-07-01 2005-01-20 Todd Maibach Film comprising therapeutic agents
JP4838723B2 (ja) * 2003-10-24 2011-12-14 アドヒーシブズ・リサーチ・インコーポレイテッド 医薬又は化粧用薬剤を送達するための迅速分解性フイルム
US20060198885A1 (en) * 2005-02-22 2006-09-07 Sun Pharmaceutical Industries Ltd. Oral pharmaceutical composition
ATE486593T1 (de) * 2006-03-16 2010-11-15 Novartis Ag Feste dosierungsform mit einem wirkstoff mit unterdrücktem geschmack
WO2008112124A2 (en) * 2007-03-07 2008-09-18 Novartis Ag Orally administrable films

Also Published As

Publication number Publication date
US20070292515A1 (en) 2007-12-20
PT1998762E (pt) 2010-11-30
AU2007227614B2 (en) 2011-01-06
BRPI0709382A2 (pt) 2011-07-12
CA2643944C (en) 2013-11-26
AU2007227614A1 (en) 2007-09-27
DE602007010254D1 (de) 2010-12-16
PL1998762T3 (pl) 2011-04-29
RU2437657C2 (ru) 2011-12-27
WO2007109057A3 (en) 2007-12-06
WO2007109057A2 (en) 2007-09-27
EP1998762B1 (en) 2010-11-03
CN101404990A (zh) 2009-04-08
CN101404990B (zh) 2012-04-25
ATE486593T1 (de) 2010-11-15
US8986735B2 (en) 2015-03-24
US20150157717A1 (en) 2015-06-11
JP2009530291A (ja) 2009-08-27
EP1998762A2 (en) 2008-12-10
RU2008140383A (ru) 2010-04-27
CA2643944A1 (en) 2007-09-27
JP5242543B2 (ja) 2013-07-24
ES2355306T3 (es) 2011-03-24

Similar Documents

Publication Publication Date Title
PL1998762T3 (pl) Stałe postacie dawkowania zawierające składnik czynny o zamaskowanym smaku
WO2007095600A3 (en) Disintegrable oral films
WO2010062688A3 (en) Dosage form for insertion into the mouth
WO2008040534A3 (en) Non-mucoadhesive film dosage forms
MX2009003771A (es) Formulaciones robustas de liberacion sostenida.
WO2007012022A3 (en) Unit dose form with ibuprofen-famotidine admixture
WO2012034079A3 (en) Macrolide dosage forms
NZ610701A (en) Once daily formulation of lacosamide
NZ585219A (en) Fast release solid formulation, preparation and use thereof
NO20070887L (no) Kornformet farmasoytisk preparat med tidsbegrenset frigivelse for oral administrasjon, og intraoral hurtig desintegrerende tablett som inneholder preparatet
MX2020011961A (es) Formas de dosis de liberacion controlada para substancias de farmaco de alta dosis, solubles en agua e higroscopicas.
WO2008039737A3 (en) A method of administering a film product containing a drug
DE602007007991D1 (de) Kleinvolumige, orale, transmukosale dosierungsformen mit sufentanil zur schmerzbehandlung
TN2010000152A1 (en) Pharmaceutical compositions
MX2010010026A (es) Agente para tratar enfermedad.
MX2011010324A (es) Tableta recubierta que se desintegra oralmente.
WO2007018588A8 (en) Stable pharmaceutical composition comprising linezolid form iv
TW200600117A (en) Preparation for oral administration
JP2009522376A5 (es)
NZ595467A (en) Sublingual pharmaceutical composition comprising a neutral oil
ECSP10010514A (es) Formulaciones mejoradas para ingredientes farmaceuticos activos de permeabilidad deficiente
GB2443793B (en) Product, method of manufacture and use
NZ592049A (en) Compositions and methods for the treatment of bowel diseases with granulated mesalamine
WO2009072334A1 (ja) 製剤用核粒子
WO2008051527A3 (en) Sustained release of agents for localized pain management

Legal Events

Date Code Title Description
FG Grant or registration