CL2009000975A1 - Compuestos derivados de quinuclidina, ligandos del receptor de acetilcolina a7; su composicion farmaceutica; su uso para el tratamiento de trastornos del sistema nervioso central, en especial afectivos y neurodegenerativos, enfermedades tales como esquizofrenia y alzheimer. - Google Patents

Compuestos derivados de quinuclidina, ligandos del receptor de acetilcolina a7; su composicion farmaceutica; su uso para el tratamiento de trastornos del sistema nervioso central, en especial afectivos y neurodegenerativos, enfermedades tales como esquizofrenia y alzheimer.

Info

Publication number
CL2009000975A1
CL2009000975A1 CL2009000975A CL2009000975A CL2009000975A1 CL 2009000975 A1 CL2009000975 A1 CL 2009000975A1 CL 2009000975 A CL2009000975 A CL 2009000975A CL 2009000975 A CL2009000975 A CL 2009000975A CL 2009000975 A1 CL2009000975 A1 CL 2009000975A1
Authority
CL
Chile
Prior art keywords
disorders
treatment
nervous system
central nervous
quinuclidine
Prior art date
Application number
CL2009000975A
Other languages
English (en)
Spanish (es)
Inventor
James H Cook
Ivar M Mcdonald
Dalton King
Richard Olson
Nenghui Wang
Christiana I Iwuagwu
F Christopher Zusi
John E Macor
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CL2009000975A1 publication Critical patent/CL2009000975A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
CL2009000975A 2008-04-23 2009-04-23 Compuestos derivados de quinuclidina, ligandos del receptor de acetilcolina a7; su composicion farmaceutica; su uso para el tratamiento de trastornos del sistema nervioso central, en especial afectivos y neurodegenerativos, enfermedades tales como esquizofrenia y alzheimer. CL2009000975A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4721108P 2008-04-23 2008-04-23
US12/423,299 US7863291B2 (en) 2008-04-23 2009-04-14 Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands

Publications (1)

Publication Number Publication Date
CL2009000975A1 true CL2009000975A1 (es) 2011-02-18

Family

ID=41215599

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009000975A CL2009000975A1 (es) 2008-04-23 2009-04-23 Compuestos derivados de quinuclidina, ligandos del receptor de acetilcolina a7; su composicion farmaceutica; su uso para el tratamiento de trastornos del sistema nervioso central, en especial afectivos y neurodegenerativos, enfermedades tales como esquizofrenia y alzheimer.

Country Status (27)

Country Link
US (1) US7863291B2 (OSRAM)
EP (1) EP2271650B1 (OSRAM)
JP (1) JP5389905B2 (OSRAM)
KR (1) KR20110015565A (OSRAM)
CN (1) CN102066384B (OSRAM)
AR (1) AR071215A1 (OSRAM)
AU (1) AU2009239575B2 (OSRAM)
BR (1) BRPI0911542A2 (OSRAM)
CA (1) CA2722325A1 (OSRAM)
CL (1) CL2009000975A1 (OSRAM)
CO (1) CO6300941A2 (OSRAM)
CY (1) CY1117045T1 (OSRAM)
DK (1) DK2271650T3 (OSRAM)
EA (1) EA017628B1 (OSRAM)
ES (1) ES2553753T3 (OSRAM)
HR (1) HRP20151111T1 (OSRAM)
HU (1) HUE028302T2 (OSRAM)
IL (1) IL208673A (OSRAM)
MX (1) MX2010011374A (OSRAM)
NZ (1) NZ588649A (OSRAM)
PE (1) PE20091977A1 (OSRAM)
PL (1) PL2271650T3 (OSRAM)
PT (1) PT2271650E (OSRAM)
SI (1) SI2271650T1 (OSRAM)
TW (1) TWI431007B (OSRAM)
WO (1) WO2009131926A1 (OSRAM)
ZA (1) ZA201007527B (OSRAM)

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Also Published As

Publication number Publication date
PE20091977A1 (es) 2010-01-15
ES2553753T3 (es) 2015-12-11
CA2722325A1 (en) 2009-10-29
PL2271650T3 (pl) 2016-03-31
US7863291B2 (en) 2011-01-04
CY1117045T1 (el) 2017-04-05
CN102066384B (zh) 2014-07-30
EP2271650A1 (en) 2011-01-12
EA201001696A1 (ru) 2011-06-30
MX2010011374A (es) 2010-11-12
HRP20151111T1 (hr) 2015-12-18
AR071215A1 (es) 2010-06-02
NZ588649A (en) 2012-05-25
CN102066384A (zh) 2011-05-18
ZA201007527B (en) 2012-03-28
BRPI0911542A2 (pt) 2015-10-13
HUE028302T2 (en) 2016-12-28
TWI431007B (zh) 2014-03-21
AU2009239575A1 (en) 2009-10-29
PT2271650E (pt) 2015-12-01
EP2271650B1 (en) 2015-09-16
JP2011518831A (ja) 2011-06-30
AU2009239575B2 (en) 2014-02-20
DK2271650T3 (en) 2015-12-21
IL208673A (en) 2013-09-30
IL208673A0 (en) 2010-12-30
SI2271650T1 (sl) 2015-12-31
WO2009131926A1 (en) 2009-10-29
TW200948812A (en) 2009-12-01
EA017628B1 (ru) 2013-01-30
US20090270405A1 (en) 2009-10-29
JP5389905B2 (ja) 2014-01-15
KR20110015565A (ko) 2011-02-16
CO6300941A2 (es) 2011-07-21

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