UY32967A - Compuestos heterocíclicos fusionados como moduladores del receptor de la orexina - Google Patents

Compuestos heterocíclicos fusionados como moduladores del receptor de la orexina

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Publication number
UY32967A
UY32967A UY0001032967A UY32967A UY32967A UY 32967 A UY32967 A UY 32967A UY 0001032967 A UY0001032967 A UY 0001032967A UY 32967 A UY32967 A UY 32967A UY 32967 A UY32967 A UY 32967A
Authority
UY
Uruguay
Prior art keywords
fusioned
heterocyclic compounds
receptor modulators
orexin receptor
orexin
Prior art date
Application number
UY0001032967A
Other languages
English (en)
Inventor
Savall Brad
Michael A Letavic
Kiev S Ly
Chandravadan R Shah
Bryan James Branstetter
Dale A Rudolph
Brock T Shiremann
Original Assignee
Janssen Farmaceutica N V
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Publication date
Application filed by Janssen Farmaceutica N V filed Critical Janssen Farmaceutica N V
Publication of UY32967A publication Critical patent/UY32967A/es

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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Abstract

Se describe ciertos 3,8-diaza-biciclo[4.2.0] octano y 3,6.diazabiciclo [3.2.0]heptano bisustituidos, que son útiles como inhibidores de la orexina. Los compuestos pueden ser útiles en composiciones farmacéuticas y métodos para el tratamiento de estados anormales, trastornos y afecciones mediadas por la actividad de la orexina, tales como insomnio.
UY0001032967A 2009-10-23 2010-10-25 Compuestos heterocíclicos fusionados como moduladores del receptor de la orexina UY32967A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25451709P 2009-10-23 2009-10-23

Publications (1)

Publication Number Publication Date
UY32967A true UY32967A (es) 2011-04-29

Family

ID=43221929

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032967A UY32967A (es) 2009-10-23 2010-10-25 Compuestos heterocíclicos fusionados como moduladores del receptor de la orexina

Country Status (10)

Country Link
US (1) US9062044B2 (es)
EP (1) EP2491031B1 (es)
JP (2) JP5848251B2 (es)
AR (1) AR078732A1 (es)
CL (1) CL2010001160A1 (es)
HK (1) HK1175462A1 (es)
PE (1) PE20110328A1 (es)
TW (1) TW201141859A (es)
UY (1) UY32967A (es)
WO (1) WO2011050202A1 (es)

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WO2011050202A1 (en) 2011-04-28
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