SI2271650T1 - Spojine kinuklidina kot ligandi receptorja alfa-7 nikotin acetilholin - Google Patents
Spojine kinuklidina kot ligandi receptorja alfa-7 nikotin acetilholinInfo
- Publication number
- SI2271650T1 SI2271650T1 SI200931324T SI200931324T SI2271650T1 SI 2271650 T1 SI2271650 T1 SI 2271650T1 SI 200931324 T SI200931324 T SI 200931324T SI 200931324 T SI200931324 T SI 200931324T SI 2271650 T1 SI2271650 T1 SI 2271650T1
- Authority
- SI
- Slovenia
- Prior art keywords
- alpha
- acetylcholine receptor
- receptor ligands
- nicotinic acetylcholine
- quinuclidine compounds
- Prior art date
Links
- 102000047725 alpha7 Nicotinic Acetylcholine Receptor Human genes 0.000 title 1
- 108700006085 alpha7 Nicotinic Acetylcholine Receptor Proteins 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 150000008584 quinuclidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4721108P | 2008-04-23 | 2008-04-23 | |
| US12/423,299 US7863291B2 (en) | 2008-04-23 | 2009-04-14 | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands |
| EP09733949.3A EP2271650B1 (en) | 2008-04-23 | 2009-04-20 | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands |
| PCT/US2009/041076 WO2009131926A1 (en) | 2008-04-23 | 2009-04-20 | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2271650T1 true SI2271650T1 (sl) | 2015-12-31 |
Family
ID=41215599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200931324T SI2271650T1 (sl) | 2008-04-23 | 2009-04-20 | Spojine kinuklidina kot ligandi receptorja alfa-7 nikotin acetilholin |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US7863291B2 (OSRAM) |
| EP (1) | EP2271650B1 (OSRAM) |
| JP (1) | JP5389905B2 (OSRAM) |
| KR (1) | KR20110015565A (OSRAM) |
| CN (1) | CN102066384B (OSRAM) |
| AR (1) | AR071215A1 (OSRAM) |
| AU (1) | AU2009239575B2 (OSRAM) |
| BR (1) | BRPI0911542A2 (OSRAM) |
| CA (1) | CA2722325A1 (OSRAM) |
| CL (1) | CL2009000975A1 (OSRAM) |
| CO (1) | CO6300941A2 (OSRAM) |
| CY (1) | CY1117045T1 (OSRAM) |
| DK (1) | DK2271650T3 (OSRAM) |
| EA (1) | EA017628B1 (OSRAM) |
| ES (1) | ES2553753T3 (OSRAM) |
| HR (1) | HRP20151111T1 (OSRAM) |
| HU (1) | HUE028302T2 (OSRAM) |
| IL (1) | IL208673A (OSRAM) |
| MX (1) | MX2010011374A (OSRAM) |
| NZ (1) | NZ588649A (OSRAM) |
| PE (1) | PE20091977A1 (OSRAM) |
| PL (1) | PL2271650T3 (OSRAM) |
| PT (1) | PT2271650E (OSRAM) |
| SI (1) | SI2271650T1 (OSRAM) |
| TW (1) | TWI431007B (OSRAM) |
| WO (1) | WO2009131926A1 (OSRAM) |
| ZA (1) | ZA201007527B (OSRAM) |
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| US8309577B2 (en) * | 2008-04-23 | 2012-11-13 | Bristol-Myers Squibb Company | Quinuclidine compounds as α-7 nicotinic acetylcholine receptor ligands |
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| JP5767643B2 (ja) | 2009-09-21 | 2015-08-19 | ギリード・サイエンシズ・インコーポレーテッド | １’−置換カルバヌクレオシド類似体の調製のためのプロセスおよび中間体 |
| US8278320B2 (en) | 2009-10-28 | 2012-10-02 | Bristol-Myers Squibb Company | Azabicyclo[2.2.1]heptane compounds as alpha-7 nicotinic acetylcholine receptor ligands |
| JP2013509417A (ja) * | 2009-10-28 | 2013-03-14 | ブリストル−マイヤーズ スクイブ カンパニー | α７ニコチン性アセチルコリン受容体リガンドとしてのアザ二環式化合物 |
| CN102791718B (zh) * | 2009-10-29 | 2015-11-25 | 百时美施贵宝公司 | 作为α-7烟碱乙酰胆碱受体配体的奎宁环化合物 |
| BR112012017484A2 (pt) * | 2010-01-14 | 2020-08-25 | Sanofi | "derivados de oxazolopirimidina 2,5-substituídos" |
| JP2013525457A (ja) | 2010-04-30 | 2013-06-20 | ブリストル−マイヤーズ スクイブ カンパニー | アルファ−７ニコチン性アセチルコリン受容体リガンドプロドラッグとしてのアザ−二環式アミンｎ−オキシド化合物 |
| PL2589592T3 (pl) | 2010-06-30 | 2019-03-29 | Fujifilm Corporation | Nowe pochodne nikotynamidu lub ich sole |
| KR101995598B1 (ko) | 2010-07-19 | 2019-07-02 | 길리애드 사이언시즈, 인코포레이티드 | 부분입체 이성질성으로 순수한 포스포라미데이트 전구약물의 제조 방법 |
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| WO2012088266A2 (en) | 2010-12-22 | 2012-06-28 | Incyte Corporation | Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3 |
| TWI565709B (zh) | 2011-07-19 | 2017-01-11 | 英菲尼提製藥股份有限公司 | 雜環化合物及其用途 |
| MY166890A (en) | 2011-08-30 | 2018-07-24 | Chdi Foundation Inc | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
| SI2766359T1 (sl) | 2011-10-14 | 2016-09-30 | Ambit Biosciences Corporation | Heterociklične spojine in njihova uporaba kot modulatorjev receptorja tirozin kinaze tipa III |
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| KR20060057569A (ko) | 2003-07-08 | 2006-05-26 | 아스트라제네카 아베 | 알파7 니코틴계 아세틸콜린 수용체와 친화도를 갖는스피로[1-아자비시클로[2.2.2]옥탄-3,5'-옥사졸리딘-2'-온] 유도체 |
| BRPI0518949A2 (pt) | 2004-12-15 | 2008-12-16 | Astrazeneca Ab | composto, uso de um composto, mÉtodo para induÇço da interrupÇço do hÁbito de fumar, composiÇço farmacÊutica, e, uso de uma composiÇço farmacÊutica |
| US20070004715A1 (en) * | 2005-06-30 | 2007-01-04 | Yifang Huang | Novel spiro-quinuclidinyl derivatives for the treatment of central nervous system disorders |
| ITMI20061279A1 (it) | 2006-06-30 | 2008-01-01 | Consiglio Nazionale Ricerche | Agonisti nicotinici selettivi per il sottotipo recettoriale alfa7,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| US8309577B2 (en) * | 2008-04-23 | 2012-11-13 | Bristol-Myers Squibb Company | Quinuclidine compounds as α-7 nicotinic acetylcholine receptor ligands |
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2009
- 2009-04-14 US US12/423,299 patent/US7863291B2/en active Active
- 2009-04-20 HU HUE09733949A patent/HUE028302T2/en unknown
- 2009-04-20 SI SI200931324T patent/SI2271650T1/sl unknown
- 2009-04-20 ES ES09733949.3T patent/ES2553753T3/es active Active
- 2009-04-20 DK DK09733949.3T patent/DK2271650T3/en active
- 2009-04-20 PL PL09733949T patent/PL2271650T3/pl unknown
- 2009-04-20 KR KR1020107026057A patent/KR20110015565A/ko not_active Ceased
- 2009-04-20 CA CA2722325A patent/CA2722325A1/en not_active Abandoned
- 2009-04-20 JP JP2011506374A patent/JP5389905B2/ja not_active Expired - Fee Related
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