CL2007003516A1 - Compuestos derivados de quinolina; procedimiento de preparacion de dichos compuestos; composicion farmaceutica; combinacion farmaceutica; y uso de los compuestos para preparar un medicamento para tratar una infeccion bacteriana. - Google Patents

Compuestos derivados de quinolina; procedimiento de preparacion de dichos compuestos; composicion farmaceutica; combinacion farmaceutica; y uso de los compuestos para preparar un medicamento para tratar una infeccion bacteriana.

Info

Publication number
CL2007003516A1
CL2007003516A1 CL200703516A CL2007003516A CL2007003516A1 CL 2007003516 A1 CL2007003516 A1 CL 2007003516A1 CL 200703516 A CL200703516 A CL 200703516A CL 2007003516 A CL2007003516 A CL 2007003516A CL 2007003516 A1 CL2007003516 A1 CL 2007003516A1
Authority
CL
Chile
Prior art keywords
compounds
quinolina
prepare
procedure
preparation
Prior art date
Application number
CL200703516A
Other languages
English (en)
Spanish (es)
Inventor
Jerome Emile George Guillemont
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CL2007003516A1 publication Critical patent/CL2007003516A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
CL200703516A 2006-12-06 2007-12-05 Compuestos derivados de quinolina; procedimiento de preparacion de dichos compuestos; composicion farmaceutica; combinacion farmaceutica; y uso de los compuestos para preparar un medicamento para tratar una infeccion bacteriana. CL2007003516A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06125521 2006-12-06

Publications (1)

Publication Number Publication Date
CL2007003516A1 true CL2007003516A1 (es) 2008-07-11

Family

ID=37944337

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200703516A CL2007003516A1 (es) 2006-12-06 2007-12-05 Compuestos derivados de quinolina; procedimiento de preparacion de dichos compuestos; composicion farmaceutica; combinacion farmaceutica; y uso de los compuestos para preparar un medicamento para tratar una infeccion bacteriana.

Country Status (29)

Country Link
US (1) US7998979B2 (cg-RX-API-DMAC7.html)
EP (1) EP2086941B1 (cg-RX-API-DMAC7.html)
JP (1) JP5356245B2 (cg-RX-API-DMAC7.html)
KR (1) KR101490221B1 (cg-RX-API-DMAC7.html)
CN (1) CN101541752B (cg-RX-API-DMAC7.html)
AR (1) AR064150A1 (cg-RX-API-DMAC7.html)
AT (1) ATE465994T1 (cg-RX-API-DMAC7.html)
AU (1) AU2007328889B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0720251B8 (cg-RX-API-DMAC7.html)
CA (1) CA2668520C (cg-RX-API-DMAC7.html)
CL (1) CL2007003516A1 (cg-RX-API-DMAC7.html)
CY (1) CY1110706T1 (cg-RX-API-DMAC7.html)
DE (1) DE602007006231D1 (cg-RX-API-DMAC7.html)
DK (1) DK2086941T3 (cg-RX-API-DMAC7.html)
ES (1) ES2344535T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20100384T1 (cg-RX-API-DMAC7.html)
IL (1) IL199081A (cg-RX-API-DMAC7.html)
JO (1) JO2685B1 (cg-RX-API-DMAC7.html)
ME (1) ME01073B (cg-RX-API-DMAC7.html)
MX (1) MX2009005980A (cg-RX-API-DMAC7.html)
NO (1) NO341995B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ576673A (cg-RX-API-DMAC7.html)
PL (1) PL2086941T3 (cg-RX-API-DMAC7.html)
PT (1) PT2086941E (cg-RX-API-DMAC7.html)
RS (1) RS51390B (cg-RX-API-DMAC7.html)
RU (1) RU2446159C2 (cg-RX-API-DMAC7.html)
SI (1) SI2086941T1 (cg-RX-API-DMAC7.html)
TW (1) TWI412364B (cg-RX-API-DMAC7.html)
WO (1) WO2008068269A1 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX358506B (es) 2012-04-27 2018-08-22 Janssen Pharmaceutica Nv Derivados de quinolina antibacterianos.
EP2841425B1 (en) 2012-04-27 2016-03-23 Janssen Pharmaceutica, N.V. Antibacterial quinoline derivatives
CN104650054B (zh) * 2013-11-25 2019-09-13 重庆医药工业研究院有限责任公司 一种抗结核菌的喹啉噻吩芳氧乙胺衍生物
WO2018048882A1 (en) 2016-09-06 2018-03-15 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
US20250214980A1 (en) 2022-03-14 2025-07-03 Slap Pharmaceuticals Llc Multicyclic compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6033389B2 (ja) * 1979-02-22 1985-08-02 日産化学工業株式会社 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤
CA2270123A1 (en) 1996-10-28 1998-05-07 Department Of The Army, U.S. Government Compounds, compositions and methods for treating antibiotic-resistant infections
AU2002355747B2 (en) * 2001-07-31 2007-12-20 Wayne State University Quinoline derivatives and use thereof as antitumor agents
JP4484703B2 (ja) * 2002-07-25 2010-06-16 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ キノリン誘導体およびミコバクテリア抑制剤としてのそれらの使用
PL1711181T3 (pl) 2004-01-23 2010-02-26 Janssen Pharmaceutica Nv Pochodne chinoliny i ich zastosowanie jako inhibitorów mykobakteryjnych
US7338949B2 (en) 2004-01-23 2008-03-04 Janssen Pharmaceutica N.V. Mycobacterial inhibitors
EA011572B9 (ru) * 2004-01-29 2018-01-31 Янссен Фармацевтика Н.В. Производные хинолина для применения в качестве микобактериальных ингибиторов
AU2005249231B2 (en) * 2004-05-28 2010-11-11 Janssen Pharmaceutica N.V. Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
PT1797115T (pt) 2004-09-28 2017-08-29 Janssen Pharmaceutica Nv Domínio de ligação de atp-sintase bacteriana

Also Published As

Publication number Publication date
NO341995B1 (no) 2018-03-12
DE602007006231D1 (de) 2010-06-10
TWI412364B (zh) 2013-10-21
NO20092540L (no) 2009-09-07
BRPI0720251B1 (pt) 2020-10-06
EP2086941A1 (en) 2009-08-12
EP2086941B1 (en) 2010-04-28
HRP20100384T1 (hr) 2010-08-31
CN101541752B (zh) 2013-07-17
ATE465994T1 (de) 2010-05-15
US7998979B2 (en) 2011-08-16
PL2086941T3 (pl) 2010-10-29
TW200845987A (en) 2008-12-01
PT2086941E (pt) 2010-07-14
KR20090087071A (ko) 2009-08-14
CA2668520C (en) 2016-01-26
CA2668520A1 (en) 2008-06-12
AU2007328889B2 (en) 2012-12-06
SI2086941T1 (sl) 2010-08-31
BRPI0720251B8 (pt) 2021-05-25
KR101490221B1 (ko) 2015-02-05
WO2008068269A1 (en) 2008-06-12
JP2010511670A (ja) 2010-04-15
AR064150A1 (es) 2009-03-18
CY1110706T1 (el) 2015-06-10
AU2007328889A1 (en) 2008-06-12
JP5356245B2 (ja) 2013-12-04
RU2446159C2 (ru) 2012-03-27
CN101541752A (zh) 2009-09-23
BRPI0720251A2 (pt) 2014-01-07
HK1137428A1 (en) 2010-07-30
MX2009005980A (es) 2009-06-16
ES2344535T3 (es) 2010-08-30
RU2009125525A (ru) 2011-01-20
US20100063061A1 (en) 2010-03-11
RS51390B (sr) 2011-02-28
NZ576673A (en) 2011-09-30
JO2685B1 (en) 2013-03-03
DK2086941T3 (da) 2010-08-09
ME01073B (me) 2012-10-20
IL199081A (en) 2013-08-29

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