CH657374A5 - Verfahren zur mikrobiologischen herstellung von nebramycin-5'. - Google Patents

Verfahren zur mikrobiologischen herstellung von nebramycin-5'. Download PDF

Info

Publication number
CH657374A5
CH657374A5 CH7558/82A CH755882A CH657374A5 CH 657374 A5 CH657374 A5 CH 657374A5 CH 7558/82 A CH7558/82 A CH 7558/82A CH 755882 A CH755882 A CH 755882A CH 657374 A5 CH657374 A5 CH 657374A5
Authority
CH
Switzerland
Prior art keywords
nebramycin
mng
culture
fermentation
production
Prior art date
Application number
CH7558/82A
Other languages
German (de)
English (en)
Inventor
Istvan Dr Ott
Gabor Dr Ambrus
Tibor Dr Balogh
Miklos Fabian
Valeria Dr Szell
Laszlo Toelgyesi
Imre Moravcsik
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Publication of CH657374A5 publication Critical patent/CH657374A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C12P19/485—Having two saccharide radicals bound through only oxygen to non-adjacent ring carbons of the cyclohexyl radical, e.g. gentamycin, kanamycin, sisomycin, verdamycin, mutamycin, tobramycin, nebramycin, antibiotics 66-40B, 66-40D, XK-62-2, 66-40, G-418, G-52
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C12P19/50—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin having two saccharide radicals bound through only oxygen to adjacent ring carbon atoms of the cyclohexyl radical, e.g. ambutyrosin, ribostamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CH7558/82A 1981-12-28 1982-12-27 Verfahren zur mikrobiologischen herstellung von nebramycin-5'. CH657374A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU813954A HU190680B (en) 1981-12-28 1981-12-28 Process for preparing 6''-0-carbamoyl-tobramycin microbiologically

Publications (1)

Publication Number Publication Date
CH657374A5 true CH657374A5 (de) 1986-08-29

Family

ID=10966213

Family Applications (2)

Application Number Title Priority Date Filing Date
CH7558/82A CH657374A5 (de) 1981-12-28 1982-12-27 Verfahren zur mikrobiologischen herstellung von nebramycin-5'.
CH3108/85A CH658072A5 (de) 1981-12-28 1982-12-27 Verfahren zur mikrobiologischen herstellung von nebramycin-2, nebramycin-5' und nebramycin-4.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH3108/85A CH658072A5 (de) 1981-12-28 1982-12-27 Verfahren zur mikrobiologischen herstellung von nebramycin-2, nebramycin-5' und nebramycin-4.

Country Status (9)

Country Link
AT (1) AT379171B (enFirst)
BE (1) BE895455A (enFirst)
CH (2) CH657374A5 (enFirst)
DE (1) DE3248420A1 (enFirst)
FI (1) FI74995C (enFirst)
FR (1) FR2519023B1 (enFirst)
GB (1) GB2114978B (enFirst)
HU (1) HU190680B (enFirst)
NL (1) NL8205011A (enFirst)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119331935B (zh) * 2024-11-01 2025-10-10 浙江大学 一种提高氨甲酰妥布霉素生产菌株发酵产量的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3691279A (en) * 1970-04-15 1972-09-12 Lilly Co Eli Antibiotic nebramycin and preparation thereof
US3853709A (en) * 1970-10-26 1974-12-10 Lilly Co Eli Process for preparing nebramycin factors ii and vii
US4032404A (en) * 1976-07-14 1977-06-28 Bristol-Myers Company Fermentation process for producing apramycin and nebramycin factor V'

Also Published As

Publication number Publication date
AT379171B (de) 1985-11-25
GB2114978A (en) 1983-09-01
FR2519023B1 (fr) 1985-10-25
DE3248420A1 (de) 1983-07-21
HU190680B (en) 1986-10-28
NL8205011A (nl) 1983-07-18
DE3248420C2 (enFirst) 1990-11-08
CH658072A5 (de) 1986-10-15
GB2114978B (en) 1985-09-11
FR2519023A1 (fr) 1983-07-01
FI824483A0 (fi) 1982-12-28
FI74995B (fi) 1987-12-31
FI824483L (fi) 1983-06-29
BE895455A (fr) 1983-06-23
ATA470482A (de) 1985-04-15
FI74995C (fi) 1988-04-11

Similar Documents

Publication Publication Date Title
EP0008031B1 (de) Verfahren zur Herstellung von 6-Amino-6-desoxy-L-sorbose
EP0366060B1 (de) Glykosidase-Inhibitor Salbostatin, Verfahren zu seiner Herstellung und seine Verwendung
DE3882453T2 (de) Verfahren zur Herstellung von Ibuprofen.
DE2167078B1 (de) Verfahren zur Herstellung einer Amylase und deren Verwendung zur Gewinnung von Maltose aus Staerke
DE2811303C3 (de) Enzymatische Komplexe, die zur Umwandlung racemischer Hydantoine in optisch aktive Aminosäuren geeignet sind, sowie deren Anwendung
DE1919837B2 (de) Leupeptine, deren Salze und Verfahren zu ihrer Herstellung
DE2402217B2 (de) Verfahren zur Herstellung von Proteinmaterial
EP0236894B1 (de) Efomycin G, seine Herstellung und seine Verwendung als Leistungsförderer bei Tieren
CH657374A5 (de) Verfahren zur mikrobiologischen herstellung von nebramycin-5'.
DE2839668A1 (de) Als antibiotika wirksame saframycine a, b, c, d und e und verfahren zu ihrer herstellung
DE3003359C2 (enFirst)
EP0019148A1 (de) Antibiotikum zur Unterdrückung des Wachstums von Mikroorganismen sowie dessen Herstellung durch Fermentation
DE940422C (de) Verfahren zur Herstellung von Vitaminsubstanzen
DE1123436B (de) Verfahren zur Herstellung neuer Wuchsstoffe
DE69307148T2 (de) Verfahren zur selektiven verbesserten herstellung des antibiotikum ge 2270 faktor a
DE1152411B (de) Verfahren zur Hydroxylierung von 12a-Desoxytetracyclinen
DE3032302A1 (de) 3,4-dihydro-4-hydroxy-5-(3-hydroxy-2-pyridinyl)-4-methyl-2h-pyrrol-2-carboxamid und seine stereoisomeren, verfahren zu ihrer herstellung, sowie die verwendung dieser verbindungen bei der bekaempfung grampositiver und gram-negativer bakterien, hefen, pilze, acholeplasmen und trichomonas vaginalis
DE2456139B2 (de) Verfahren zur Herstellung des Antibiotikums 20.798 R.P
DE1792403C (de) Verfahren zur biotechnischen Herstellung von L Lysin
DE1517837C (de) Verfahren zur biochemischen Herstellung von delta-(N-Acetyl)-L-Ornithin
DE1617951C3 (de) Verfahren zur Herstellung von Kasugamycin
AT204695B (de) Verfahren zur Gewinnung von Thiactin
AT200724B (de) Verfahren zur Gewinnung von LLD-aktiven Substanzen der Vitamin B12-Gruppe
EP0049410B1 (de) Wässriges Nährmedium zur Anzucht von Mikroorganismen
EP0248238A2 (de) Verfahren zur fermentativen Herstellung von L-Isoleucin aus D,L-alpha-Hydroxybutyrat

Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased