CH652395A5 - 2(1h)-pyridinon-derivate, ihre herstellung und sie enthaltende pharmazeutische zubereitungen. - Google Patents
2(1h)-pyridinon-derivate, ihre herstellung und sie enthaltende pharmazeutische zubereitungen. Download PDFInfo
- Publication number
- CH652395A5 CH652395A5 CH7325/81A CH732581A CH652395A5 CH 652395 A5 CH652395 A5 CH 652395A5 CH 7325/81 A CH7325/81 A CH 7325/81A CH 732581 A CH732581 A CH 732581A CH 652395 A5 CH652395 A5 CH 652395A5
- Authority
- CH
- Switzerland
- Prior art keywords
- compounds
- phenyl
- formula
- carbon atoms
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH166880 | 1980-03-03 | ||
| CH166980 | 1980-03-03 | ||
| CH571780 | 1980-07-25 | ||
| CH794780 | 1980-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH652395A5 true CH652395A5 (de) | 1985-11-15 |
Family
ID=27428258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH7325/81A CH652395A5 (de) | 1980-03-03 | 1981-02-27 | 2(1h)-pyridinon-derivate, ihre herstellung und sie enthaltende pharmazeutische zubereitungen. |
Country Status (16)
| Country | Link |
|---|---|
| CA (1) | CA1183533A (enExample) |
| CH (1) | CH652395A5 (enExample) |
| DE (1) | DE3106460A1 (enExample) |
| DK (1) | DK94481A (enExample) |
| ES (1) | ES499971A0 (enExample) |
| FI (1) | FI810558L (enExample) |
| FR (1) | FR2477148A1 (enExample) |
| GB (1) | GB2070606B (enExample) |
| IL (1) | IL62246A (enExample) |
| IT (1) | IT1142458B (enExample) |
| NL (1) | NL8100964A (enExample) |
| NZ (1) | NZ196385A (enExample) |
| PT (1) | PT72596B (enExample) |
| SE (1) | SE8101336L (enExample) |
| WO (1) | WO1981002575A1 (enExample) |
| YU (1) | YU51581A (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL65278A0 (en) * | 1981-03-30 | 1982-05-31 | Sterling Drug Inc | 3-amino-5-(substituted)-2(1h)-pyridinones and corresponding 3-cyano compounds,their preparation and pharmaceutical compositions containing them |
| US4515797A (en) * | 1981-09-08 | 1985-05-07 | Sterling Drug Inc. | 3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof |
| US4465686A (en) * | 1981-09-08 | 1984-08-14 | Sterling Drug Inc. | 5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation |
| US4432979A (en) * | 1981-10-26 | 1984-02-21 | William H. Rorer, Inc. | Pyridone compounds |
| US4539321A (en) * | 1981-10-26 | 1985-09-03 | William H. Rorer, Inc. | 5-Diaza-aryl-3-substituted pyridone compounds |
| US4514400A (en) * | 1981-10-26 | 1985-04-30 | William H. Rorer, Inc. | Cardiotonic 5-heteroaryl-pyridone |
| US4593028A (en) * | 1981-10-26 | 1986-06-03 | William H. Rorer, Inc. | 5-hetero aryl-substituted-2-pyridones useful as cardiotonic agents for treatment of congestive heart failure |
| FR2527206B1 (fr) * | 1982-05-18 | 1986-12-05 | Sandoz Sa | Nouveaux derives de la 2(1h)-pyridinone, leur preparation et leur utilisation comme medicaments |
| AT384021B (de) * | 1982-05-18 | 1987-09-25 | Sandoz Ag | Verfahren zur herstellung neuer 2(1h)-pyridinon- derivate und ihrer salze |
| FR2529891A1 (fr) * | 1982-07-12 | 1984-01-13 | Nativelle Sa Ets | Derives du pyridyl-3 alcoxy-5 pyrazole, procede de preparation et application en therapeutique |
| IT8367883A0 (it) * | 1982-08-23 | 1983-08-22 | Rorer Int Overseas | Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche |
| US4503061A (en) * | 1983-07-22 | 1985-03-05 | Warner-Lambert Company | Substituted phenyl-pyridinones as cardiotonic agents |
| IL69407A (en) * | 1982-08-23 | 1987-10-20 | Warner Lambert Co | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
| US4517192A (en) * | 1983-01-31 | 1985-05-14 | Sterling Drug Inc. | 6-Alkyl-5-[4-(alkylsulfinyl or alkylsulfonyl)phenyl]-2(1H)-pyridinones and their use as cardiatonics |
| ES521644A0 (es) * | 1983-04-20 | 1985-10-16 | Quimicos Y Farmaceuticos Abel | Un nuevo procedimiento para la preparacion de 5-azinil-1,2-dihidroazin-2-onas. |
| US4568751A (en) * | 1983-04-29 | 1986-02-04 | Merrell Dow Pharmaceuticals Inc. | 5-Acyl-2-(1H)-pyridinones |
| DE3406329A1 (de) * | 1984-02-22 | 1985-08-22 | Merck Patent Gmbh, 6100 Darmstadt | Pyridone |
| DE3685840D1 (de) | 1985-04-30 | 1992-08-06 | Dresden Arzneimittel | 3-cyan-pyridine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung. |
| US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
| US4785005A (en) * | 1986-06-25 | 1988-11-15 | Rorer Pharmaceutical Corporation | 6-(6-alkylpyridone)-carbostyril compounds and their cardiotonic uses |
| GB8809481D0 (en) * | 1988-04-21 | 1988-05-25 | Smith Kline French Lab | Chemical compounds |
| US5254571A (en) * | 1988-04-21 | 1993-10-19 | Smith Kline & French Laboratories Ltd. | Chemical compounds |
| GB8923131D0 (en) * | 1989-10-13 | 1989-11-29 | Smith Kline French Lab | Chemical compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3355278A (en) * | 1961-03-13 | 1967-11-28 | Hooker Chemical Corp | Herbicidal composition and method |
| NL6816241A (enExample) * | 1967-12-01 | 1969-06-03 | ||
| FR2050940A5 (enExample) * | 1969-06-30 | 1971-04-02 | Rhone Poulenc Sa | |
| US3666765A (en) * | 1969-10-27 | 1972-05-30 | Union Carbide Corp | Synthesis of 2-pyridones and derivatives thereof |
| US3721676A (en) * | 1969-11-12 | 1973-03-20 | Merck & Co Inc | Certain 3-amino-2(1h)pyridones |
| BE758759A (fr) * | 1969-11-12 | 1971-05-10 | Merck & Co Inc | Pyridones anti-inflammatoires |
| US4038396A (en) * | 1975-02-24 | 1977-07-26 | Merck & Co., Inc. | Anti-inflammatory oxazole[4,5-b]pyridines |
| US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
-
1981
- 1981-02-21 DE DE19813106460 patent/DE3106460A1/de not_active Withdrawn
- 1981-02-24 FI FI810558A patent/FI810558L/fi not_active Application Discontinuation
- 1981-02-27 WO PCT/CH1981/000023 patent/WO1981002575A1/de not_active Ceased
- 1981-02-27 CH CH7325/81A patent/CH652395A5/de not_active IP Right Cessation
- 1981-02-27 NL NL8100964A patent/NL8100964A/nl not_active Application Discontinuation
- 1981-02-27 GB GB8106335A patent/GB2070606B/en not_active Expired
- 1981-02-27 FR FR8104152A patent/FR2477148A1/fr active Granted
- 1981-03-02 YU YU00515/81A patent/YU51581A/xx unknown
- 1981-03-02 SE SE8101336A patent/SE8101336L/xx not_active Application Discontinuation
- 1981-03-02 ES ES499971A patent/ES499971A0/es active Granted
- 1981-03-02 IL IL62246A patent/IL62246A/xx unknown
- 1981-03-02 IT IT47920/81A patent/IT1142458B/it active
- 1981-03-02 CA CA000372050A patent/CA1183533A/en not_active Expired
- 1981-03-02 PT PT72596A patent/PT72596B/pt unknown
- 1981-03-02 DK DK94481A patent/DK94481A/da not_active Application Discontinuation
- 1981-03-02 NZ NZ196385A patent/NZ196385A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3106460A1 (de) | 1982-01-28 |
| CA1183533A (en) | 1985-03-05 |
| IL62246A (en) | 1984-09-30 |
| ES8301469A1 (es) | 1982-12-01 |
| IT1142458B (it) | 1986-10-08 |
| IL62246A0 (en) | 1981-05-20 |
| PT72596A (en) | 1981-04-01 |
| ES499971A0 (es) | 1982-12-01 |
| WO1981002575A1 (fr) | 1981-09-17 |
| FR2477148A1 (fr) | 1981-09-04 |
| NZ196385A (en) | 1983-12-16 |
| FR2477148B1 (enExample) | 1983-09-02 |
| GB2070606A (en) | 1981-09-09 |
| FI810558A7 (fi) | 1981-09-04 |
| PT72596B (en) | 1982-07-13 |
| NL8100964A (nl) | 1981-10-01 |
| FI810558L (fi) | 1981-09-04 |
| YU51581A (en) | 1983-12-31 |
| GB2070606B (en) | 1984-02-29 |
| DK94481A (da) | 1981-09-04 |
| SE8101336L (sv) | 1981-09-04 |
| IT8147920A0 (it) | 1981-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |