CH626349A5 - - Google Patents

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Publication number
CH626349A5
CH626349A5 CH995076A CH995076A CH626349A5 CH 626349 A5 CH626349 A5 CH 626349A5 CH 995076 A CH995076 A CH 995076A CH 995076 A CH995076 A CH 995076A CH 626349 A5 CH626349 A5 CH 626349A5
Authority
CH
Switzerland
Prior art keywords
phenyl
melting point
group
acid
formula
Prior art date
Application number
CH995076A
Other languages
German (de)
English (en)
Inventor
Hanns Dr Ahrens
Henning Dr Koch
Eberhard Dr Schroeder
Helmut Dr Biere
Joachim-Friedrich Dr Kapp
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of CH626349A5 publication Critical patent/CH626349A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CH995076A 1975-08-08 1976-08-04 CH626349A5 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2536003A DE2536003C2 (de) 1975-08-08 1975-08-08 Pyrazol-Derivate, ihre Herstellung und diese enthaltende pharmazeutische Derivate

Publications (1)

Publication Number Publication Date
CH626349A5 true CH626349A5 (xx) 1981-11-13

Family

ID=5953847

Family Applications (2)

Application Number Title Priority Date Filing Date
CH995076A CH626349A5 (xx) 1975-08-08 1976-08-04
CH847280A CH631165A5 (de) 1975-08-08 1980-11-14 Verfahren zur herstellung neuer pyrazol-derivate.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH847280A CH631165A5 (de) 1975-08-08 1980-11-14 Verfahren zur herstellung neuer pyrazol-derivate.

Country Status (5)

Country Link
US (1) US4042706A (xx)
JP (1) JPS6037099B2 (xx)
CH (2) CH626349A5 (xx)
DE (1) DE2536003C2 (xx)
FR (1) FR2320095A1 (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3068860D1 (en) * 1979-05-21 1984-09-13 Schering Ag Process for the preparation of pyrazole derivatives
IE59813B1 (en) * 1986-05-09 1994-04-06 Warner Lambert Co Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
EP0272704A3 (en) * 1986-12-26 1990-11-22 Sanwa Kagaku Kenkyusho Co., Ltd. Use of pyrazole derivatives in the treatment of immunity diseases and nephropathy
US5051518A (en) * 1987-05-29 1991-09-24 Ortho Pharmaceutical Corporation Pharmacologically active 2- and 3-substituted (1',5'-diaryl-3-pyrazolyl)-N-hydroxypropanamides
CS264450B1 (en) * 1987-07-17 1989-08-14 Hajicek Josef Process for preparing calcium salt of 1-/phenyl-3/4-chlorphenyl/pyrazol-4-ylacetic acid
IT1226387B (it) * 1988-07-08 1991-01-15 Seuref Ag Processo per la preparazione di acidi 1,4-diaril-3-pirazol-acetici
PH27357A (en) * 1989-09-22 1993-06-21 Fujisawa Pharmaceutical Co Pyrazole derivatives and pharmaceutical compositions comprising the same
US4956379A (en) * 1990-02-13 1990-09-11 Bristol-Myers Squibb Company Pyrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
CA2036192A1 (en) 1990-02-13 1991-08-14 Nicholas Meanwell Heterocyclic carboxylic acids and esters
US9226505B2 (en) * 2011-09-23 2016-01-05 Bayer Intellectual Property Gmbh 4-substituted 1-phenylpyrazole-3-carboxylic acid derivatives as agents against abiotic plant stress

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE755924A (fr) * 1969-09-12 1971-02-15 Byk Gulden Lomberg Chem Fab Derives d'acide pyrazole-4-acetique, leur procede de preparation et medicaments en contenant
BE759032A (fr) * 1969-11-17 1971-04-30 Takeda Chemical Industries Ltd Acide 3,5-diphenyl-4-pyrazole acetique ou ses derives 1-substitues ou leurs esters
US3984431A (en) * 1972-03-15 1976-10-05 Claude Gueremy Derivatives of pyrazole-5-acetic acid
JPS5113154B2 (xx) * 1973-04-17 1976-04-26
DE2347015C2 (de) * 1973-09-14 1985-12-12 Schering AG, 1000 Berlin und 4709 Bergkamen Neue Pyrazolyloxyessigsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel
US3903106A (en) * 1974-04-12 1975-09-02 Lilly Co Eli Pyrazole-3-carboxylic acids
US3899508A (en) * 1974-04-12 1975-08-12 Lilly Co Eli 5-(2-Aminophenyl)pyrazole-3-carboxylic acids and esters thereof

Also Published As

Publication number Publication date
JPS5236666A (en) 1977-03-22
DE2536003A1 (de) 1977-02-24
US4042706A (en) 1977-08-16
FR2320095A1 (fr) 1977-03-04
CH631165A5 (de) 1982-07-30
JPS6037099B2 (ja) 1985-08-24
DE2536003C2 (de) 1985-11-14
FR2320095B1 (xx) 1980-02-01

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Legal Events

Date Code Title Description
PUE Assignment

Owner name: MEDIOLANUM FARMACEUTICI S.P.A.

PL Patent ceased