CH625502A5 - - Google Patents

Download PDF

Info

Publication number
CH625502A5
CH625502A5 CH419480A CH419480A CH625502A5 CH 625502 A5 CH625502 A5 CH 625502A5 CH 419480 A CH419480 A CH 419480A CH 419480 A CH419480 A CH 419480A CH 625502 A5 CH625502 A5 CH 625502A5
Authority
CH
Switzerland
Prior art keywords
formula
radical
hydrogen atom
compounds
acid
Prior art date
Application number
CH419480A
Other languages
German (de)
English (en)
Inventor
Derek Victor Gardner
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of CH625502A5 publication Critical patent/CH625502A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH419480A 1975-07-24 1980-05-29 CH625502A5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB30923/75A GB1493848A (en) 1975-07-24 1975-07-24 Aryltetralins

Publications (1)

Publication Number Publication Date
CH625502A5 true CH625502A5 (es) 1981-09-30

Family

ID=10315210

Family Applications (3)

Application Number Title Priority Date Filing Date
CH947976A CH624382A5 (es) 1975-07-24 1976-07-23
CH419480A CH625502A5 (es) 1975-07-24 1980-05-29
CH419380A CH625781A5 (es) 1975-07-24 1980-05-29

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH947976A CH624382A5 (es) 1975-07-24 1976-07-23

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH419380A CH625781A5 (es) 1975-07-24 1980-05-29

Country Status (19)

Country Link
US (1) US4322370A (es)
JP (1) JPS5214756A (es)
AT (1) AT347442B (es)
AU (1) AU500207B2 (es)
BE (1) BE844300A (es)
CA (1) CA1072119A (es)
CH (3) CH624382A5 (es)
DE (1) DE2632862A1 (es)
DK (1) DK334976A (es)
ES (2) ES450113A1 (es)
FR (1) FR2318625A1 (es)
GB (1) GB1493848A (es)
HU (1) HU177289B (es)
IE (1) IE43144B1 (es)
IL (1) IL50058A (es)
NL (1) NL7607812A (es)
NZ (1) NZ181467A (es)
SE (1) SE7608119L (es)
ZA (1) ZA764351B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2507181A1 (fr) 1981-06-05 1982-12-10 Sanofi Sa Nouveaux ethers de phenol actifs sur le systeme cardiovasculaire, leur procede de preparation et leur utilisation dans des medicaments
US4839104A (en) * 1987-06-11 1989-06-13 Pfizer, Inc. Process for preparing sertraline intermediates
ES2064228B1 (es) * 1992-10-19 1995-09-01 Uriach & Cia Sa J Nuevas tetralonas con actividad farmacologica, composiciones que las contienen y procedimiento para su preparacion.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2820817A (en) * 1954-02-04 1958-01-21 Mcneilab Inc Oxygenated indan compounds and method of making the same
US3565956A (en) * 1964-10-16 1971-02-23 Sterling Drug Inc Amino-lower-alkoxy-5-alkylidene-dibenzo(a,d)cycloheptenes
US3388121A (en) * 1964-12-16 1968-06-11 Squibb & Sons Inc Tetrahydrobenzocyclohexene and cycloheptene ethers
US3476767A (en) * 1965-10-11 1969-11-04 Ciba Geigy Corp 1,2-diaryl - 6 - tertiary amino lower-alkoxy-3,4-dihydro naphthalenes
US3641152A (en) * 1968-09-23 1972-02-08 Warner Lambert Pharmaceutical 3 4-dihydronaphthalenoneoxy-2-hydroxy-propylamines
US3671530A (en) * 1970-08-27 1972-06-20 Miles Lab Certain substituted 1,3-bisdilower-alkylaminoethoxy-indans
US3988475A (en) * 1974-02-05 1976-10-26 Istituto Luso Farmaco D'italia S.R.L. Phenoxyalkylamines

Also Published As

Publication number Publication date
ATA537176A (de) 1978-05-15
US4322370A (en) 1982-03-30
IE43144L (en) 1977-01-24
IL50058A0 (en) 1976-09-30
SE7608119L (sv) 1977-01-25
CH624382A5 (es) 1981-07-31
HU177289B (en) 1981-09-28
CA1072119A (en) 1980-02-19
ZA764351B (en) 1977-07-27
BE844300A (fr) 1977-01-19
ES450113A1 (es) 1977-12-01
CH625781A5 (es) 1981-10-15
NZ181467A (en) 1978-09-25
AU500207B2 (en) 1979-05-10
FR2318625B1 (es) 1978-12-15
FR2318625A1 (fr) 1977-02-18
AU1625476A (en) 1978-02-02
GB1493848A (en) 1977-11-30
AT347442B (de) 1978-12-27
ES461082A1 (es) 1978-06-16
DK334976A (da) 1977-01-25
JPS5214756A (en) 1977-02-03
DE2632862A1 (de) 1977-02-03
IL50058A (en) 1979-10-31
IE43144B1 (en) 1980-12-31
NL7607812A (nl) 1977-01-26

Similar Documents

Publication Publication Date Title
DE1643224C3 (de) 1 -Phenyl-2-aminoäthanolderivate und deren Säureadditionssalze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
CH626611A5 (es)
DE1795836C2 (de) 3-MethyI-2,3,4,4a-tetrahydro-lH- pyrazine [1,2-f] phenanthridin
DE2809625A1 (de) Acetamidderivate und sie enthaltendes arzneimittel
DE2500110A1 (de) 3-aryloxy-3-phenylpropylamine und verfahren zu ihrer herstellung
CH649986A5 (de) Aminoaether und verfahren zur herstellung derselben.
DE2160148C2 (de) Arzneimittel und bestimmte Sulfoxide als solche
CH625502A5 (es)
DE2451474A1 (de) Neue phenylpropenylaminderivate
AT344151B (de) Verfahren zur herstellung von neuen naphthalinderivaten
DE2314639A1 (de) Pharmakodynamisch aktive aminoalkyloximaether
DE3112984A1 (de) 2-(3-(4-(3-chlor-4-fluorphenyl)-1-piperazinyl) propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-on dessen pharmazeutische anwendung und herstellung
CH635312A5 (de) Alpha-aryl-alpha,alpha-bis(omega-(disubstituierte amino)-alkyl)acetamide und deren saeureanlagerungssalze, verfahren zu ihrer herstellung sowie sie enthaltende arzneimittelzubereitungen.
DE1568929A1 (de) Aminosubstituierte Indane und Tetraline sowie Verfahren zu deren Herstellung
CH419105A (de) Verfahren zur Herstellung analeptisch wirksamer N-substituierter Amino-norcamphanderivate bzw. von deren Säureadditionssalzen und quaternären Ammoniumverbindungen
DE2462966C2 (de) Derivate des 3-Amino-4-acetyl-5-methylpyrrols und diese enthaltende pharmazeutische Zubereitungen
DE1770915A1 (de) Neue Isoindolino-sulfonylharnstoffderivate und Verfahren zu ihrer Herstellung
DE2951912A1 (de) Neues verfahren zur herstellung von piperidyl-indol-derivaten, hiernach erhaltene neue verbindung und deren salze, ihre anwendung als arzneimittel und die sie enthaltenden pharmazeutischen zusammensetzungen
DE1545961A1 (de) Verfahren zur Herstellung von gamma-Picolylderivaten
DE1543496A1 (de) Verfahren zur Herstellung von Phenoxyessigsaeureamiden
DE2753878A1 (de) Derivate des 1-(3,5-dichlorphenyl)- piperazins, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE1931927A1 (de) Neue Cyclohexylaminderivate
JPH04270223A (ja) 療法的に活性なオルガノシラン誘導体を含む医薬組成物およびその調製方法
BE643853A (es)
DE2855878A1 (de) 3-aminosubstituierte 1,5-cyclohexadiencarbonsaeure und deren derivate

Legal Events

Date Code Title Description
PL Patent ceased