ES461082A1 - Un procedimiento para la preparacion de compuestos polici- clicos. - Google Patents

Un procedimiento para la preparacion de compuestos polici- clicos.

Info

Publication number
ES461082A1
ES461082A1 ES461082A ES461082A ES461082A1 ES 461082 A1 ES461082 A1 ES 461082A1 ES 461082 A ES461082 A ES 461082A ES 461082 A ES461082 A ES 461082A ES 461082 A1 ES461082 A1 ES 461082A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
phenyl
image
polycyclic compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES461082A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES461082A1 publication Critical patent/ES461082A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un procedimiento para la preparación de compuestos policiclicos de fórmula (II): (ver fórmula I) O una sal del mismo, donde R1 es un grupo fenilo o naftilo o un grupo fenilo o naftilo sustituido; R2 es un grupo (ver fórmula II)
ES461082A 1975-07-24 1977-07-27 Un procedimiento para la preparacion de compuestos polici- clicos. Expired ES461082A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB30923/75A GB1493848A (en) 1975-07-24 1975-07-24 Aryltetralins

Publications (1)

Publication Number Publication Date
ES461082A1 true ES461082A1 (es) 1978-06-16

Family

ID=10315210

Family Applications (2)

Application Number Title Priority Date Filing Date
ES450113A Expired ES450113A1 (es) 1975-07-24 1976-07-23 Un procedimiento para la preparacion de compuestos polici- clicos.
ES461082A Expired ES461082A1 (es) 1975-07-24 1977-07-27 Un procedimiento para la preparacion de compuestos polici- clicos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES450113A Expired ES450113A1 (es) 1975-07-24 1976-07-23 Un procedimiento para la preparacion de compuestos polici- clicos.

Country Status (19)

Country Link
US (1) US4322370A (es)
JP (1) JPS5214756A (es)
AT (1) AT347442B (es)
AU (1) AU500207B2 (es)
BE (1) BE844300A (es)
CA (1) CA1072119A (es)
CH (3) CH624382A5 (es)
DE (1) DE2632862A1 (es)
DK (1) DK334976A (es)
ES (2) ES450113A1 (es)
FR (1) FR2318625A1 (es)
GB (1) GB1493848A (es)
HU (1) HU177289B (es)
IE (1) IE43144B1 (es)
IL (1) IL50058A (es)
NL (1) NL7607812A (es)
NZ (1) NZ181467A (es)
SE (1) SE7608119L (es)
ZA (1) ZA764351B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2507181A1 (fr) 1981-06-05 1982-12-10 Sanofi Sa Nouveaux ethers de phenol actifs sur le systeme cardiovasculaire, leur procede de preparation et leur utilisation dans des medicaments
US4839104A (en) * 1987-06-11 1989-06-13 Pfizer, Inc. Process for preparing sertraline intermediates
ES2064228B1 (es) * 1992-10-19 1995-09-01 Uriach & Cia Sa J Nuevas tetralonas con actividad farmacologica, composiciones que las contienen y procedimiento para su preparacion.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2820817A (en) * 1954-02-04 1958-01-21 Mcneilab Inc Oxygenated indan compounds and method of making the same
US3565956A (en) * 1964-10-16 1971-02-23 Sterling Drug Inc Amino-lower-alkoxy-5-alkylidene-dibenzo(a,d)cycloheptenes
US3388121A (en) * 1964-12-16 1968-06-11 Squibb & Sons Inc Tetrahydrobenzocyclohexene and cycloheptene ethers
US3476767A (en) * 1965-10-11 1969-11-04 Ciba Geigy Corp 1,2-diaryl - 6 - tertiary amino lower-alkoxy-3,4-dihydro naphthalenes
US3641152A (en) * 1968-09-23 1972-02-08 Warner Lambert Pharmaceutical 3 4-dihydronaphthalenoneoxy-2-hydroxy-propylamines
US3671530A (en) * 1970-08-27 1972-06-20 Miles Lab Certain substituted 1,3-bisdilower-alkylaminoethoxy-indans
US3988475A (en) * 1974-02-05 1976-10-26 Istituto Luso Farmaco D'italia S.R.L. Phenoxyalkylamines

Also Published As

Publication number Publication date
IE43144B1 (en) 1980-12-31
NL7607812A (nl) 1977-01-26
CH625502A5 (es) 1981-09-30
ATA537176A (de) 1978-05-15
US4322370A (en) 1982-03-30
DK334976A (da) 1977-01-25
AT347442B (de) 1978-12-27
ZA764351B (en) 1977-07-27
BE844300A (fr) 1977-01-19
JPS5214756A (en) 1977-02-03
FR2318625A1 (fr) 1977-02-18
GB1493848A (en) 1977-11-30
ES450113A1 (es) 1977-12-01
AU500207B2 (en) 1979-05-10
IL50058A0 (en) 1976-09-30
IE43144L (en) 1977-01-24
IL50058A (en) 1979-10-31
DE2632862A1 (de) 1977-02-03
CH624382A5 (es) 1981-07-31
CH625781A5 (es) 1981-10-15
NZ181467A (en) 1978-09-25
HU177289B (en) 1981-09-28
FR2318625B1 (es) 1978-12-15
AU1625476A (en) 1978-02-02
CA1072119A (en) 1980-02-19
SE7608119L (sv) 1977-01-25

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