CH623037A5 - - Google Patents

Download PDF

Info

Publication number
CH623037A5
CH623037A5 CH743277A CH743277A CH623037A5 CH 623037 A5 CH623037 A5 CH 623037A5 CH 743277 A CH743277 A CH 743277A CH 743277 A CH743277 A CH 743277A CH 623037 A5 CH623037 A5 CH 623037A5
Authority
CH
Switzerland
Prior art keywords
compound
formula
reacted
iii
compounds
Prior art date
Application number
CH743277A
Other languages
English (en)
French (fr)
Inventor
Kanji Noda
Akira Nakagawa
Satoru Miyata
Yoichi Nakashima
Hiroyuki Ide
Original Assignee
Hisamitsu Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co filed Critical Hisamitsu Pharmaceutical Co
Publication of CH623037A5 publication Critical patent/CH623037A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH743277A 1976-06-22 1977-06-17 CH623037A5 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7410476A JPS52156862A (en) 1976-06-22 1976-06-22 Novel indoleacetic acid ester derivatives

Publications (1)

Publication Number Publication Date
CH623037A5 true CH623037A5 (ru) 1981-05-15

Family

ID=13537537

Family Applications (1)

Application Number Title Priority Date Filing Date
CH743277A CH623037A5 (ru) 1976-06-22 1977-06-17

Country Status (10)

Country Link
US (1) US4165428A (ru)
JP (1) JPS52156862A (ru)
AU (1) AU511662B2 (ru)
CA (1) CA1069889A (ru)
CH (1) CH623037A5 (ru)
DE (1) DE2727829A1 (ru)
FR (1) FR2355822A1 (ru)
GB (1) GB1588352A (ru)
NL (1) NL7706799A (ru)
SE (1) SE427659B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2943127A1 (de) * 1979-10-25 1981-05-14 Troponwerke GmbH & Co KG, 5000 Köln (1-(4-chlorbenzoyl)-methoxy-2-methyl-3-indol) -acetoxyessigsaeuremonohydrat, verfahren zur herstellung sowie dessen verwendung in arzneimitteln
DE2943125A1 (de) * 1979-10-25 1981-05-14 Troponwerke GmbH & Co KG, 5000 Köln Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol acetoxyessigsaeure
IT1133963B (it) * 1980-10-21 1986-07-24 D & D Srl Derivati piridossinici ad attivita' terapeutica,procedimento per la loro preparazione e relative composizioni farmaceutiche
US4464379A (en) * 1981-06-01 1984-08-07 A. Nattermann & Cie Gmbh Indol acetic acid derivatives and anti-inflamatory and related uses thereof
US4428962A (en) 1981-10-30 1984-01-31 Schering Corporation Indoles in treatment of peptic ulcers
JPS58134077A (ja) * 1982-02-02 1983-08-10 Ss Pharmaceut Co Ltd 新規なインド−ル酢酸エステル誘導体及びその製造法
JPS59204172A (ja) * 1983-04-28 1984-11-19 Kowa Co アセメタシンの製造法
JPS6028957A (ja) * 1983-07-27 1985-02-14 Kaken Pharmaceut Co Ltd インドリル酢酸およびフエニル酢酸のエステル誘導体およびその製造法
DE3416895A1 (de) * 1984-05-08 1985-11-14 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von acemetacin
KR940007001A (ko) * 1992-09-16 1994-04-26 최승주 새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제
MY186191A (en) * 2013-06-28 2021-06-30 Malaysian Palm Oil Board Isolation of novel bioactive compound obtained from oil palm base materials

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470203A (en) * 1964-02-01 1969-09-30 Merck & Co Inc Intermediates for preparing 1-aroylindole-3-alkanoic acids
US3271394A (en) * 1964-12-31 1966-09-06 Merck & Co Inc Alpha-indolyl-3-acetic acid esters
JPS4927190A (ru) * 1972-07-07 1974-03-11
DE2234651C3 (de) * 1972-07-14 1978-11-09 Troponwerke Gmbh & Co Kg, 5000 Koeln Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen
HU168745B (ru) * 1972-08-24 1976-07-28
DE2257867C2 (de) * 1972-11-25 1982-09-23 Troponwerke GmbH & Co KG, 5000 Köln Verfahren zur Herstellung von 1-Benzoylindol-Derivaten

Also Published As

Publication number Publication date
AU2626877A (en) 1979-01-04
SE7706976L (sv) 1977-12-23
NL7706799A (nl) 1977-12-27
US4165428A (en) 1979-08-21
JPS52156862A (en) 1977-12-27
FR2355822A1 (fr) 1978-01-20
FR2355822B1 (ru) 1980-04-04
DE2727829A1 (de) 1978-01-05
GB1588352A (en) 1981-04-23
CA1069889A (en) 1980-01-15
JPS6254106B2 (ru) 1987-11-13
AU511662B2 (en) 1980-08-28
SE427659B (sv) 1983-04-25

Similar Documents

Publication Publication Date Title
CH617919A5 (en) Process for the preparation of new derivatives of esters of phenyl-acetic acid
JPS623152B2 (ru)
IE49866B1 (en) Amide derivatives,process for their manufacture and pharmaceutical or veterinary compositions containing them
CA1137985A (fr) Procede de preparation de nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
CH623037A5 (ru)
EP0040573B1 (fr) Dérivés de l'acide 4-hydroxy 3-quinoléine carboxylique substitués en 2, leur préparation, leur application comme médicament, les compositions les renfermant et les intermédiaires nouveaux obtenus
CH659469A5 (fr) Derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur preparation et les medicaments et compositions les renfermant.
FR2567520A1 (fr) Nouvelles phenyl-naphthyridines, leur procede de preparation, medicaments les contenant, notamment anti-ulceres
LU82844A1 (fr) Nouveaux composes heterocycliques azotes anti-inflammatoires et immunoregulateurs et composition pharmaceutique les contenant
EP0214004B1 (fr) Dérivés de l'acide 4-OH quinoléine carboxylique substitué en 2 par un groupement dihydroxylé éventuellement éthérifié ou estérifié, procédé et inter-médiaires de préparation, leur application comme médicaments et les compositions les renfermant
EP0176444B1 (fr) Nouveau procédé de préparation de dérivés du 4 H-1,2-4-triazole, nouveaux triazoles ainsi obtenus, leur applicication comme médicaments et les compositions pharmaceutiques les renfermant
CA1211105A (fr) Procede pour la preparation de derives de p-acylaminophenol et derives obtenus par ce procede
FR2551063A1 (fr) Nouveaux dimethyl-2,5 pyrroles, leur procede de preparation et leur application en therapeutique
EP0183584B1 (fr) Nouveaux esters dérivés de l'acide 4-hydroxy 3-quinoléine carboxylique substitué en 2 par une chaîne alpha-hydroxylée, leur préparation, leur application comme médicaments et les compositions les renfermant
FR2468574A1 (fr) Derives de l'acide 4-chlorobiphenylalcoxy-acetique, procedes pour leur preparation et compositions pharmaceutiques en contenant
CH640818A5 (fr) Derives d'acide naphtyl-1 acetique, leurs procedes de preparation et medicament les contenant.
CH601228A5 (en) Antiinflammatory indomethacin esters active topically and orally
JPH0144708B2 (ru)
JPS604809B2 (ja) 新規な２‐（ｍ‐ベンゾイル）フエニルプロピオン酸エステル誘導体
CA1200554A (fr) Procede de preparation de nouveaux derives de l'aminomethyl 14-indole-4-methanol et de leurs sels
CA1105022A (fr) Procede de preparation de nouveaux derives de la benzophenone
CH652715A5 (fr) Composition pharmaceutique topique contenant des thiazoles.
KR100246821B1 (ko) 비스테로이드성 소염진통제인 티아펜타렌카르복실산 유도체
CA1115276A (fr) Procede de preparation de nouveaux derives de l'acide 2/(4-quinoleinyl) amino/ 5-fluorobenzoique
FR2600059A1 (fr) Derives de l'acide benzoique et leur procede de preparation

Legal Events

Date Code Title Description
PL Patent ceased