JPS52156862A - Novel indoleacetic acid ester derivatives - Google Patents

Novel indoleacetic acid ester derivatives

Info

Publication number
JPS52156862A
JPS52156862A JP7410476A JP7410476A JPS52156862A JP S52156862 A JPS52156862 A JP S52156862A JP 7410476 A JP7410476 A JP 7410476A JP 7410476 A JP7410476 A JP 7410476A JP S52156862 A JPS52156862 A JP S52156862A
Authority
JP
Japan
Prior art keywords
acid ester
ester derivatives
novel
indoleacetic acid
pyridyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7410476A
Other languages
English (en)
Other versions
JPS6254106B2 (ja
Inventor
Kanji Noda
Akira Nakagawa
Satoru Miyata
Yoichi Nakajima
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP7410476A priority Critical patent/JPS52156862A/ja
Priority to CA279,880A priority patent/CA1069889A/en
Priority to US05/804,280 priority patent/US4165428A/en
Priority to SE7706976A priority patent/SE427659B/xx
Priority to FR7718590A priority patent/FR2355822A1/fr
Priority to CH743277A priority patent/CH623037A5/fr
Priority to DE19772727829 priority patent/DE2727829A1/de
Priority to NL7706799A priority patent/NL7706799A/xx
Priority to AU26268/77A priority patent/AU511662B2/en
Priority to GB24926/77A priority patent/GB1588352A/en
Publication of JPS52156862A publication Critical patent/JPS52156862A/ja
Publication of JPS6254106B2 publication Critical patent/JPS6254106B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP7410476A 1976-06-22 1976-06-22 Novel indoleacetic acid ester derivatives Granted JPS52156862A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP7410476A JPS52156862A (en) 1976-06-22 1976-06-22 Novel indoleacetic acid ester derivatives
CA279,880A CA1069889A (en) 1976-06-22 1977-06-06 Process for preparing indoleacetic acid ester derivatives
US05/804,280 US4165428A (en) 1976-06-22 1977-06-07 Indoleacetic acid ester derivatives
SE7706976A SE427659B (sv) 1976-06-22 1977-06-16 Forfarande for framstellning av terapeutiskt aktiva 1-(p-klorbensyl)-2-metyl-5-metoxi-3-indonylettiksyra-pyridylmetylestrar och derivat derav
FR7718590A FR2355822A1 (fr) 1976-06-22 1977-06-17 Derives d'esters de l'acide indolacetique. utiles comme anti-inflammatoires et analgesiques
CH743277A CH623037A5 (ja) 1976-06-22 1977-06-17
DE19772727829 DE2727829A1 (de) 1976-06-22 1977-06-21 Indolessigsaeureesterderivate
NL7706799A NL7706799A (nl) 1976-06-22 1977-06-21 Werkwijze ter bereiding van een geneesmiddel, werkwijze ter bereiding van de indoolazijnzure ester als actieve component en het gevormde geneesmiddel.
AU26268/77A AU511662B2 (en) 1976-06-22 1977-06-21 Indoleacetic acid ester derivatives
GB24926/77A GB1588352A (en) 1976-06-22 1977-06-22 Indoleacetic acid ester derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7410476A JPS52156862A (en) 1976-06-22 1976-06-22 Novel indoleacetic acid ester derivatives

Publications (2)

Publication Number Publication Date
JPS52156862A true JPS52156862A (en) 1977-12-27
JPS6254106B2 JPS6254106B2 (ja) 1987-11-13

Family

ID=13537537

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7410476A Granted JPS52156862A (en) 1976-06-22 1976-06-22 Novel indoleacetic acid ester derivatives

Country Status (10)

Country Link
US (1) US4165428A (ja)
JP (1) JPS52156862A (ja)
AU (1) AU511662B2 (ja)
CA (1) CA1069889A (ja)
CH (1) CH623037A5 (ja)
DE (1) DE2727829A1 (ja)
FR (1) FR2355822A1 (ja)
GB (1) GB1588352A (ja)
NL (1) NL7706799A (ja)
SE (1) SE427659B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58134077A (ja) * 1982-02-02 1983-08-10 Ss Pharmaceut Co Ltd 新規なインド−ル酢酸エステル誘導体及びその製造法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2943125A1 (de) * 1979-10-25 1981-05-14 Troponwerke GmbH & Co KG, 5000 Köln Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol acetoxyessigsaeure
DE2943127A1 (de) * 1979-10-25 1981-05-14 Troponwerke GmbH & Co KG, 5000 Köln (1-(4-chlorbenzoyl)-methoxy-2-methyl-3-indol) -acetoxyessigsaeuremonohydrat, verfahren zur herstellung sowie dessen verwendung in arzneimitteln
IT1133963B (it) * 1980-10-21 1986-07-24 D & D Srl Derivati piridossinici ad attivita' terapeutica,procedimento per la loro preparazione e relative composizioni farmaceutiche
US4464379A (en) * 1981-06-01 1984-08-07 A. Nattermann & Cie Gmbh Indol acetic acid derivatives and anti-inflamatory and related uses thereof
US4428962A (en) 1981-10-30 1984-01-31 Schering Corporation Indoles in treatment of peptic ulcers
JPS59204172A (ja) * 1983-04-28 1984-11-19 Kowa Co アセメタシンの製造法
JPS6028957A (ja) * 1983-07-27 1985-02-14 Kaken Pharmaceut Co Ltd インドリル酢酸およびフエニル酢酸のエステル誘導体およびその製造法
DE3416895A1 (de) * 1984-05-08 1985-11-14 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von acemetacin
KR940007001A (ko) * 1992-09-16 1994-04-26 최승주 새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제
MY186191A (en) * 2013-06-28 2021-06-30 Malaysian Palm Oil Board Isolation of novel bioactive compound obtained from oil palm base materials

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4927190A (ja) * 1972-07-07 1974-03-11
JPS4982657A (ja) * 1972-11-25 1974-08-08
US3886279A (en) * 1972-08-24 1975-05-27 Chinoin Gyogyszer Es Vegyeszet Anti-inflammatory analgesic method of treatment and composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470203A (en) * 1964-02-01 1969-09-30 Merck & Co Inc Intermediates for preparing 1-aroylindole-3-alkanoic acids
US3271394A (en) * 1964-12-31 1966-09-06 Merck & Co Inc Alpha-indolyl-3-acetic acid esters
DE2234651C3 (de) * 1972-07-14 1978-11-09 Troponwerke Gmbh & Co Kg, 5000 Koeln Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4927190A (ja) * 1972-07-07 1974-03-11
US3886279A (en) * 1972-08-24 1975-05-27 Chinoin Gyogyszer Es Vegyeszet Anti-inflammatory analgesic method of treatment and composition
JPS4982657A (ja) * 1972-11-25 1974-08-08

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58134077A (ja) * 1982-02-02 1983-08-10 Ss Pharmaceut Co Ltd 新規なインド−ル酢酸エステル誘導体及びその製造法
JPS6237623B2 (ja) * 1982-02-02 1987-08-13 Ss Pharmaceutical Co

Also Published As

Publication number Publication date
SE7706976L (sv) 1977-12-23
CA1069889A (en) 1980-01-15
AU2626877A (en) 1979-01-04
FR2355822A1 (fr) 1978-01-20
US4165428A (en) 1979-08-21
SE427659B (sv) 1983-04-25
FR2355822B1 (ja) 1980-04-04
DE2727829A1 (de) 1978-01-05
NL7706799A (nl) 1977-12-27
AU511662B2 (en) 1980-08-28
CH623037A5 (ja) 1981-05-15
GB1588352A (en) 1981-04-23
JPS6254106B2 (ja) 1987-11-13

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