CH615172A5 - - Google Patents

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Publication number
CH615172A5
CH615172A5 CH1195574A CH1195574A CH615172A5 CH 615172 A5 CH615172 A5 CH 615172A5 CH 1195574 A CH1195574 A CH 1195574A CH 1195574 A CH1195574 A CH 1195574A CH 615172 A5 CH615172 A5 CH 615172A5
Authority
CH
Switzerland
Prior art keywords
dihydro
oxepin
acetic acid
formula
oxodibenz
Prior art date
Application number
CH1195574A
Other languages
German (de)
English (en)
Inventor
Grover Cleveland Dr Helsley
Arthur Raymond Dr Mcfadden
David Hoffmann
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CH615172A5 publication Critical patent/CH615172A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12[b,e]-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CH1195574A 1973-09-06 1974-09-03 CH615172A5 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39480173A 1973-09-06 1973-09-06
US05/459,774 US4585788A (en) 1973-09-06 1974-04-10 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives

Publications (1)

Publication Number Publication Date
CH615172A5 true CH615172A5 (fr) 1980-01-15

Family

ID=27014870

Family Applications (2)

Application Number Title Priority Date Filing Date
CH675378A CH609960A5 (fr) 1973-09-06 1974-09-03
CH1195574A CH615172A5 (fr) 1973-09-06 1974-09-03

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH675378A CH609960A5 (fr) 1973-09-06 1974-09-03

Country Status (17)

Country Link
US (1) US4585788A (fr)
JP (1) JPS5058084A (fr)
AT (1) AT342053B (fr)
AU (1) AU499709B2 (fr)
CA (1) CA1153384A (fr)
CH (2) CH609960A5 (fr)
DE (1) DE2442060A1 (fr)
DK (1) DK470574A (fr)
FI (1) FI66368C (fr)
FR (1) FR2242976B1 (fr)
GB (1) GB1481866A (fr)
IE (1) IE39835B1 (fr)
IL (1) IL45585A (fr)
NL (1) NL7411565A (fr)
NO (1) NO142397C (fr)
SE (1) SE7411156L (fr)
YU (2) YU239574A (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56156273A (en) 1980-03-31 1981-12-02 Dainippon Pharmaceut Co Ltd Acetic derivative
DE3125374A1 (de) * 1981-06-27 1983-01-13 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von heteroaryl- und dibenzoxepinalkansaeuren
US4576960A (en) * 1981-12-23 1986-03-18 Hoechst Roussel Pharmaceuticals Incorporated 6,11-Dihydro-11-oxo-dibenz[b,e]oxepin derivatives
US4515946A (en) * 1981-12-23 1985-05-07 Hoechst-Roussel Pharmaceuticals Inc. 6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives
US4526891A (en) * 1983-03-10 1985-07-02 Hoechst Roussel Pharmaceuticals Inc. Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz[b,e]oxepins
EP0188802A3 (fr) * 1984-12-26 1986-08-20 Kyowa Hakko Kogyo Co., Ltd. Dérivé de dibenzo (b,e) oxépine et agent antiallergique
FR2580280B1 (fr) * 1985-04-11 1987-05-22 Synthelabo Derives d'acide dibenzo(be)oxepinne-acetique, leur preparation et leur application en therapeutique
JPS6310784A (ja) * 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
FR2608606B1 (fr) * 1986-12-22 1989-03-10 Synthelabo Derives d'acide dibenzo(be)oxepinne-acetique, leur preparation et leur application en therapeutique
US4882351A (en) * 1987-10-14 1989-11-21 Roussel Uclaf Tricyclic compounds
US4994463A (en) * 1987-12-14 1991-02-19 Kyowa Hakko Kogyo Co., Ltd. Tricyclic thromboxane A2 antagonists
US5242931A (en) * 1988-06-09 1993-09-07 Kyowa Hakko Kogyo Co., Ltd. Tricyclic compounds as TXA2 antagonists
US4999363A (en) * 1988-06-09 1991-03-12 Kyowa Hakko Kogyo Co., Ltd. Tricyclic compounds
US5175286A (en) * 1988-09-20 1992-12-29 Hisamitsu Pharmaceutical Co., Inc. Dibenz[b,e]oxepin derivatives
TW209861B (fr) * 1989-08-25 1993-07-21 Hoechst Roussel Pharma
US5840749A (en) * 1989-08-25 1998-11-24 Hoechst Marion Roussel, Inc. N-hydroxy-dibenz b,e!oxepinalkylamines, N-hydroxy-dibenz b,e!oxepinalkanoic acid amides and related heterocyclic analogues
US5574173A (en) * 1993-12-06 1996-11-12 Schering Corporation Tricyclic derivatives, compositions and methods of use
US6989462B2 (en) * 2003-03-25 2006-01-24 Sanofi-Aventis Deutschland Gmbh Synthesis of 2-chloromethyl-6-methylbenzoic ester
US7687646B2 (en) * 2006-03-28 2010-03-30 Azad Pharmaceutical Ingredients, Ag Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof
ES2399453T3 (es) * 2006-08-21 2013-04-01 Sumitomo Chemical Company Limited Método para producir éster metílico del ácido 2-(4-toxicarbonilmetilfenoximetil)benzoico
JP5139016B2 (ja) * 2006-10-02 2013-02-06 住友化学株式会社 オキソジベンゾオキセピン酢酸第3級アルキルエステルの製造方法
WO2008041734A1 (fr) * 2006-10-02 2008-04-10 Sumitomo Chemical Company, Limited Ester d'alkyle tertiaire d'acide oxodibenzoxépinacétique
ES2433715T3 (es) * 2008-07-16 2013-12-12 Crystal Pharma, S.A.U. Procedimiento de obtención de olopatadina e intermedios
CN106518833A (zh) * 2015-09-15 2017-03-22 江苏吉贝尔药业股份有限公司 一种新的6,11-二氢-11-氧代二苯并[b,e]噁庚因-2-乙酸制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS47425Y1 (fr) * 1968-03-14 1972-01-10
JPS48389Y1 (fr) * 1968-10-15 1973-01-08
US3702852A (en) * 1970-02-24 1972-11-14 Squibb & Sons Inc Carboxylated dibenzoxazepines and dibenzothiazepines
US3758528A (en) * 1970-03-13 1973-09-11 Science Union & Cie Tricyclic compounds
US3714201A (en) * 1970-11-24 1973-01-30 Squibb & Sons Inc 5,11-dihydrodibenzoxa(or thia) zepine derivatives

Also Published As

Publication number Publication date
IE39835L (en) 1975-03-06
AT342053B (de) 1978-03-10
NO142397B (no) 1980-05-05
SE7411156L (fr) 1975-03-07
US4585788A (en) 1986-04-29
ATA716474A (de) 1977-07-15
DE2442060A1 (de) 1975-05-07
NO743203L (fr) 1975-04-01
AU7296274A (en) 1976-04-15
YU233880A (en) 1983-04-27
IE39835B1 (en) 1979-01-17
AU499709B2 (en) 1979-05-03
CA1153384A (fr) 1983-09-06
IL45585A0 (en) 1974-11-29
FR2242976A1 (fr) 1975-04-04
DK470574A (fr) 1975-05-05
FI66368C (fi) 1984-10-10
GB1481866A (en) 1977-08-03
FR2242976B1 (fr) 1978-07-21
YU239574A (en) 1982-06-18
FI258374A (fr) 1975-03-07
JPS5058084A (fr) 1975-05-20
NL7411565A (nl) 1975-03-10
FI66368B (fi) 1984-06-29
CH609960A5 (fr) 1979-03-30
IL45585A (en) 1977-06-30
NO142397C (no) 1980-08-13

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Legal Events

Date Code Title Description
PL Patent ceased