CH608189A5 - - Google Patents
Info
- Publication number
- CH608189A5 CH608189A5 CH1658874A CH1658874A CH608189A5 CH 608189 A5 CH608189 A5 CH 608189A5 CH 1658874 A CH1658874 A CH 1658874A CH 1658874 A CH1658874 A CH 1658874A CH 608189 A5 CH608189 A5 CH 608189A5
- Authority
- CH
- Switzerland
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (38)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1658874A CH608189A5 (ko) | 1974-12-13 | 1974-12-13 | |
NL7512208.A NL157295B (nl) | 1974-12-13 | 1975-10-17 | Werkwijze voor het bereiden van een als roentgencontrastmiddel bruikbaar preparaat en werkwijze voor het bereiden van een daartoe geschikt 5-n-gesubstitueerd 2,4,6-trijoodisoftaalzuur bis(dihydroxypropylamide). |
DE19752547789 DE2547789C3 (de) | 1974-12-13 | 1975-10-24 | 5-Hydroxypropionylamino-2,4,6-trijodisophthalsäure-bis-(dihydroxypropylamide), Verfahren zu ihrer Herstellung und diese enthaltende Röntgenkontrastmittel |
BG031456A BG26512A3 (bg) | 1974-12-13 | 1975-11-11 | Метод за получаване на амиди на 2,4,6-трийод-изофталовата киселина |
ES442651A ES442651A1 (es) | 1974-12-13 | 1975-11-14 | Procedimiento para la preparacion de las nuevas bis-(dihi- droxipropil-amidas) de acido 5-hidroxipropionilamino-2,4,6- triyodo-isoftalico facilmente solubles en agua. |
IL48484A IL48484A (en) | 1974-12-13 | 1975-11-17 | 5-hydroxypropionylamino-2,4,6-triiodo-isophthalic acid bis-(dihydroxypropylamides),their preparation and use as x-ray contrast agents |
ZA757222A ZA757222B (en) | 1974-12-13 | 1975-11-18 | New x-ray contrast media which are readily soluble in water,their use and processes for their preparation |
US05/634,836 US4001323A (en) | 1974-12-13 | 1975-11-24 | Water-soluble, non-ionizing hydroxy-containing amide derivatives of 2,4,6-triiodo-isophthalic acid |
IN2245/CAL/75A IN142089B (ko) | 1974-12-13 | 1975-11-25 | |
GB4862075A GB1472050A (en) | 1974-12-13 | 1975-11-26 | Non-ionic x-ray contrast agents |
CA240,580A CA1046082A (en) | 1974-12-13 | 1975-11-26 | Derivatives of 2,4,6-triiodo-isophthalic acid |
AR261439A AR211853A1 (es) | 1974-12-13 | 1975-12-02 | Procedimiento para la preparacion de las nuevas bis-(dihidroxipropi-amidas)de acido 5-hidroxipropionilamino-2,4,6-triyodoisoftalico facilmente solubles en agua |
MX004201U MX3174E (es) | 1974-12-13 | 1975-12-03 | Procedimiento para la preparacion de amidas de acido 2 , 4 , 6 - tri yodo - isoftalico , facilmente solubles en el agua |
MX817775U MX5979E (es) | 1974-12-13 | 1975-12-03 | Procedimiento para la preparacion de bis-(dihidroxipropilamidas)del acido 5-hidroxipropionilamino-2,4,6-triyodo isoftalico |
MX817875U MX6161E (es) | 1974-12-13 | 1975-12-03 | Procedimiento para la preparacion de bis-(dihidroxipropilamidas)del acido 5-hidroxipropionilamino-2,4,6-triyodo-isoftalico,facilmente solubles en el agua |
AT925075A AT340582B (de) | 1974-12-13 | 1975-12-05 | Leicht wasserlosliche, nicht ionische rontgenkontrastmittel |
BE162511A BE836355A (fr) | 1974-12-13 | 1975-12-05 | Agents de constraste radiographique non ioniques facilement solubles dans l'eau et procede pour les preparer |
HUSA2864A HU170216B (ko) | 1974-12-13 | 1975-12-10 | |
PL1975185427A PL96082B1 (pl) | 1974-12-13 | 1975-12-10 | Sposob wytwarzania nowych bis-/dwuhydroksypropyloamidow/kwasu 5-hydroksypropionyloamino-2,4,6-trojjodoizoftalowego |
SU752196656A SU628813A3 (ru) | 1974-12-13 | 1975-12-10 | Способ получени амидов 5-оксипропиониламино-2,4,6-трийодизофталевой кислоты |
IE2706/75A IE42620B1 (en) | 1974-12-13 | 1975-12-11 | Non-ionic x-ray contras agents |
DD190060A DD122475A5 (ko) | 1974-12-13 | 1975-12-11 | |
FR7537934A FR2293919A1 (fr) | 1974-12-13 | 1975-12-11 | Agents de contraste radiographique non ioniques facilement solubles dans l'eau et procede pour les preparer |
SE7514076A SE409993B (sv) | 1974-12-13 | 1975-12-12 | Rontgenkontrastmedel |
JP50147492A JPS5182236A (en) | 1974-12-13 | 1975-12-12 | Mizuniiyoseino 2 4 66 toryoodooisofutarusanamidoruino seiho |
CS758475A CS194234B2 (en) | 1974-12-13 | 1975-12-12 | Method of production of the bis-/dihydrixypropylamides/ of the acid 5-hydroxypropionylamino-2,4,6-troiodisophtale |
SI7513155A SI7513155A8 (sl) | 1974-12-13 | 1975-12-12 | Postopek za pripravo bis-(dihidroksipropilamidov) 5-hidroksipropionilamino-2,4,6-trijod-izoftalove kisline, ki so lahko topni v vodi |
AU87516/75A AU475785B2 (en) | 1974-12-13 | 1975-12-12 | X-ray contrast agents |
YU3155/75A YU40448B (en) | 1974-12-13 | 1975-12-12 | Process for preparing bis-(dihydroxy-propyl-amides) of 5-hydroxy-propionylamino-2,4,6-triiodo-isophthalic acid which are easily soluble in water |
NO754241A NO145096C (no) | 1974-12-13 | 1975-12-12 | Nye 5-hydroksypropionylamino-2,4,6-trijod-sioftalsyre-bis(dihydroksypropylamider) for anvendelse i roentgenkontrastmidler, fremgangsmaate for fremstilling av forbindelsene samt roentgenkontrastmidler inneholdende disse |
RO7584187A RO69615A (ro) | 1974-12-13 | 1975-12-12 | Procedeu pentru prepararea unor 2,4,6-triiod-izo-ftaloilamide |
DK567475A DK147336C (da) | 1974-12-13 | 1975-12-12 | 5-hydroxypropionylamino-2,4,6-triiod-isophthalsyre-bis(dihydroxypropylamider) til anvendelse i roentgenkontrastmidler og roentgenkontrastmidler indeholdende disse forbindelser |
PH7517872A PH12321A (en) | 1974-12-13 | 1975-12-15 | Water-soluble,non-ionixing derivatives of 2,4,6-triiodo-isophthalic acid |
AT925175A AT342579B (de) | 1974-12-13 | 1975-12-22 | Verfahren zur herstellung von neuen, racemischen oder in der l-form vorliegenden 5-hydroxypropionylamino-2,4,6-trijod-isophthalsaure-bis- (dihydroxypropylamiden) |
AT481377A AT349450B (de) | 1974-12-13 | 1977-07-06 | Verfahren zur herstellung von neuen, racemischen oder in der l-form vorliegenden 5- hydroxypropionylamino-2,4,6-trijod-isophthal- saeure-bis-(dihydroxypropylamiden) |
AT481277A AT349449B (de) | 1974-12-13 | 1977-07-06 | Verfahren zur herstellung von neuen, racemischen oder in der l-form vorliegenden 5- hydroxypropionylamino-2,4,6-trijod-isophthal- saeure-bis-(dihydroxypropylamiden) |
YU1967/83A YU41540B (en) | 1974-12-13 | 1983-09-30 | Process for preparing bis-(dihydroxy-propilamides) of 5-hydroxy-propionylamido-2,4,6-triido-isophthalic acid, which are readily soluble in water |
YU1966/83A YU42882B (en) | 1974-12-13 | 1983-09-30 | Process for preparing bis-(dihydroxy-propylamides) of 5-hydroxy-propionylamino-2,4,6-triiodo-isophthalic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1658874A CH608189A5 (ko) | 1974-12-13 | 1974-12-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH608189A5 true CH608189A5 (ko) | 1978-12-29 |
Family
ID=4418593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1658874A CH608189A5 (ko) | 1974-12-13 | 1974-12-13 |
Country Status (29)
Country | Link |
---|---|
US (1) | US4001323A (ko) |
JP (1) | JPS5182236A (ko) |
AR (1) | AR211853A1 (ko) |
AT (2) | AT340582B (ko) |
AU (1) | AU475785B2 (ko) |
BE (1) | BE836355A (ko) |
BG (1) | BG26512A3 (ko) |
CA (1) | CA1046082A (ko) |
CH (1) | CH608189A5 (ko) |
CS (1) | CS194234B2 (ko) |
DD (1) | DD122475A5 (ko) |
DK (1) | DK147336C (ko) |
ES (1) | ES442651A1 (ko) |
FR (1) | FR2293919A1 (ko) |
GB (1) | GB1472050A (ko) |
HU (1) | HU170216B (ko) |
IE (1) | IE42620B1 (ko) |
IL (1) | IL48484A (ko) |
IN (1) | IN142089B (ko) |
MX (1) | MX3174E (ko) |
NL (1) | NL157295B (ko) |
NO (1) | NO145096C (ko) |
PH (1) | PH12321A (ko) |
PL (1) | PL96082B1 (ko) |
RO (1) | RO69615A (ko) |
SE (1) | SE409993B (ko) |
SU (1) | SU628813A3 (ko) |
YU (2) | YU40448B (ko) |
ZA (1) | ZA757222B (ko) |
Families Citing this family (101)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1495679A (en) * | 1974-06-17 | 1977-12-21 | Mallinckrodt Inc | Substituted isophthalamic acids |
US4314055A (en) * | 1975-09-29 | 1982-02-02 | Mallinckrodt, Inc. | 3,5-Disubstituted-2,4,6-triiodoanilides of polyhydroxy-monobasic acids |
JPS52130923A (en) * | 1976-04-27 | 1977-11-02 | Mallinckrodt Chemical Works | Xxray photographic agent |
GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
CH626873A5 (ko) * | 1977-03-28 | 1981-12-15 | Bracco Ind Chimica Spa | |
DE2909439A1 (de) * | 1979-03-08 | 1980-09-18 | Schering Ag | Neue nichtionische roentgenkontrastmittel |
US4256729A (en) * | 1979-03-23 | 1981-03-17 | Mallinckrodt, Inc. | N,N'-Bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-keto-L-gulonamido)isophthalamide and radiological compositions containing same |
NL8002388A (nl) * | 1979-05-21 | 1980-11-25 | Mallinckrodt Inc | Roentgencontrastmiddel. |
IT1207226B (it) * | 1979-08-09 | 1989-05-17 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono. |
DE3001292A1 (de) * | 1980-01-11 | 1981-07-16 | Schering Ag Berlin Und Bergkamen, 1000 Berlin | Nichtionische 5-c-substituierte 2,4,6-trijod-isophthalsaeure-derivate |
DE3038853A1 (de) | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii) |
DE3150917A1 (de) * | 1981-12-18 | 1983-06-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | "2-amino-1-(1,3-dioxolan-4-yl)-ethanol-verbindungen, deren herstellung und verwendung zur weiterverarbeitung" |
DE3150916A1 (de) * | 1981-12-18 | 1983-06-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel" |
US4396598A (en) * | 1982-01-11 | 1983-08-02 | Mallinckrodt, Inc. | Triiodoisophthalamide X-ray contrast agent |
US5204086A (en) * | 1982-10-01 | 1993-04-20 | Nycomed Imaging As | X-ray contrast agent |
US4584401A (en) * | 1983-10-20 | 1986-04-22 | Biophysica Foundation | Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media |
DE3689330T2 (de) * | 1985-08-09 | 1994-05-19 | Cook Imaging Corp | Nichtionische polyolkontrastmittel aus ionischen kontrastmitteln. |
US5035877A (en) * | 1985-08-09 | 1991-07-30 | Cook Imaging Corporation | Non-ionic contrast media from ionic contrast media |
KR960016747B1 (ko) * | 1987-05-22 | 1996-12-20 | 브라코 인터내셔날 비. 브이 | 5-아실아미노-2,4,6-트리요오도-또는 트리브로모-벤조산 유도체의 제조 방법 |
IL94718A (en) * | 1989-07-05 | 1994-10-21 | Schering Ag | Non-ionic carboxamide contrast agent and method of preparation |
US5698739A (en) * | 1989-07-05 | 1997-12-16 | Schering Aktiengesellschaft | Carboxamide non-ionic contrast media |
GB8919929D0 (en) * | 1989-09-04 | 1989-10-18 | Nycomed As | Compositions |
US5232685A (en) * | 1989-11-03 | 1993-08-03 | Schering Aktiengesellschaft | Nonionic x-ray contrast medium with high iodine content |
DE3937118A1 (de) * | 1989-11-03 | 1991-05-08 | Schering Ag | Nichtionische roentgenkontrastmittel mit hohem jodgehalt |
US5614638A (en) * | 1989-11-29 | 1997-03-25 | Bracco International B.V. | Nonionic radiographic contrast agents |
US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
US4997983A (en) * | 1990-01-31 | 1991-03-05 | Mallinckrodt, Inc. | Process for production of ioversol |
IT1248741B (it) * | 1991-02-26 | 1995-01-26 | Bracco Spa | Processo di concentrazione e di purificazione di composti organici |
US5169864A (en) * | 1991-11-15 | 1992-12-08 | Baxter International Inc. | Unbuffered premixed ranitidine formulation |
US5463080A (en) * | 1992-08-27 | 1995-10-31 | Bracco International B.V. | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents |
IT1256162B (it) * | 1992-10-27 | 1995-11-29 | Zambon Spa | Processo per la preparazione di un intermedio della sintesi organica |
IT1256163B (it) * | 1992-10-27 | 1995-11-29 | Zambon Spa | Processo per la preparazione di un intermedio della sintesi organica |
IT1256248B (it) * | 1992-12-24 | 1995-11-29 | Bracco Spa | Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x |
US5424056A (en) * | 1993-03-01 | 1995-06-13 | Sterling Wintrhop Inc. | X-ray contrast compositions containing iodoaniline derivatives and pharmaceutically acceptable clays |
US5330740A (en) * | 1993-03-01 | 1994-07-19 | Sterling Winthrop Inc. | Compositions of iodoaniline derivatives in film-forming materials for visualization of the gastrointestinal tract |
IL110391A (en) | 1993-07-30 | 1998-12-06 | Zambon Spa | Process for the formation of infamidol |
IT1271469B (it) * | 1993-09-10 | 1997-05-28 | Zambon Spa | Processo per la preparazione di 5-ammino-2,2-dialchil-1,3 diossani |
IT1274027B (it) * | 1994-03-03 | 1997-07-14 | Zambon Spa | Processo per la preparazione e purificazione di mezzi di contrasto iodurati |
IT1275429B (it) * | 1995-05-18 | 1997-08-07 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di composti organici |
KR100255914B1 (ko) * | 1995-05-23 | 2000-05-01 | 안토니오 칸탈루피 | 디카르복실산 디클로라이드의 제조 방법 |
PL187308B1 (pl) | 1995-05-23 | 2004-06-30 | Bracco Imaging Spa | Sposób wytwarzania dichlorku kwasu dikarboksylowego i sposób oczyszczania i izolacji dichlorku kwasu dikarboksylowego |
PT101720A (pt) * | 1995-06-08 | 1997-01-31 | Hovione Sociedade Quimica S A | Processo para a purificacao e cristalizacao de iopamidol |
ATE187437T1 (de) * | 1995-09-08 | 1999-12-15 | Bracco Int Bv | Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide |
US5866100A (en) * | 1995-12-19 | 1999-02-02 | Bracco Research S.A. | Compositions for imaging of the gastrointestinal tract |
IT1283319B1 (it) * | 1996-03-29 | 1998-04-16 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati |
IT1288114B1 (it) * | 1996-06-13 | 1998-09-10 | Fructamine Spa | Processo per la purificazione di un intermedio |
GB9618056D0 (en) * | 1996-08-29 | 1996-10-09 | Nycomed Imaging As | Process |
US5705692A (en) * | 1996-09-27 | 1998-01-06 | Abbott Laboratories | Process for the preparation of iohexol |
US5861138A (en) * | 1996-11-20 | 1999-01-19 | Hoechst Celanese Corp. | Ligands for MRI contrast agent |
US5861140A (en) * | 1996-11-20 | 1999-01-19 | Hoechst Celanese Corp. | Tripodal paramagnetic contrast agents for MR imaging |
GB9624612D0 (en) * | 1996-11-26 | 1997-01-15 | Nycomed Imaging As | Process |
IT1286522B1 (it) * | 1996-12-04 | 1998-07-15 | Dibra Spa | Processo per la preparazione di derivati dell'acido 5-ammino-2,4,6- triiodo-1,3-benzenedicarbossilico |
IT1289520B1 (it) * | 1996-12-24 | 1998-10-15 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati |
IT1289521B1 (it) * | 1996-12-24 | 1998-10-15 | Zambon Spa | Processo per la purificazione di un intermedio |
IT1289519B1 (it) * | 1996-12-24 | 1998-10-15 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati |
DE966428T1 (de) * | 1997-02-11 | 2000-06-29 | Bracco International B.V., Amsterdam | Verfahren zur kritallisation von (s)-n-n'-bis [2-hydroxy-1-(hydroxymethyl) ethyl]-5-[(2-hydroxy-1-xopropyl) amino]-2,4,6-trirodo-1,3-benzoldicarboxamid aus linearem oder verzweigtem (c5-c6) alkohol oder gemischen davon |
IT1292037B1 (it) * | 1997-05-30 | 1999-01-25 | Bracco Spa | Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen- |
US5869025A (en) * | 1997-08-21 | 1999-02-09 | Hoechst Celanese Corporation | Tripodal aromatic heterocycle carboxamide MRI contrast agents |
US5858329A (en) * | 1997-08-21 | 1999-01-12 | Hoechst Celanese Corporation | MRI diagnostic procedures using tripodal pyridinyl metal complexes |
US5820851A (en) * | 1997-08-21 | 1998-10-13 | Hoechst Celanese Corporation | Tripodal pyridine ligands as MRI contrast agents |
US5824288A (en) * | 1997-08-21 | 1998-10-20 | Hoechst Celanese Corporation | Thio-substituted pyridines as MRI ligand precursors |
US5869026A (en) * | 1997-08-21 | 1999-02-09 | Hoechst Celanese Corp. | Tripodal carboxamide ligands for MRI contrast agents |
US6262303B1 (en) | 1998-05-08 | 2001-07-17 | Dibra S.P.A. | Process for the preparation of S-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)-amino]-2,4,6-triiodo-1,3-benzenedicarboxamide |
IT1299202B1 (it) * | 1998-05-08 | 2000-02-29 | Dibra Spa | Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo |
IT1302200B1 (it) * | 1998-09-11 | 2000-07-31 | Dibra Spa | PROCESSO PER LA PREPARAZIONE DELLA S-N,N'-BIS°2-IDROSSI-1-(IDROSSIMETIL)ETILé-5-°(2-IDROSSI-1- |
GB9825095D0 (en) * | 1998-11-16 | 1999-01-13 | Nycomed Imaging As | Chemical process |
US6803485B2 (en) * | 1999-02-26 | 2004-10-12 | Bracco Imaging S.P.A. | Process for the preparation of iopamidol |
SE520688C2 (sv) * | 2000-04-11 | 2003-08-12 | Bone Support Ab | Ett injicerbart ersättningsmaterial för benmineral |
SE517168C2 (sv) * | 2000-07-17 | 2002-04-23 | Bone Support Ab | En komposition för ett injicerbart ersättningsmaterial för benmineral |
AU2002245169A1 (en) | 2000-11-10 | 2002-07-08 | Wm. Marsh Rice University | Fullerene (c60)-based x-ray contrast agent for diagnostic imaging |
IT1319671B1 (it) * | 2000-12-01 | 2003-10-23 | Bracco Spa | Processo per la preparazione di (s)-n,n'-bis(2-idrossi-1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino) |
SE522098C2 (sv) * | 2001-12-20 | 2004-01-13 | Bone Support Ab | Ett nytt benmineralsubstitut |
SE0300620D0 (sv) * | 2003-03-05 | 2003-03-05 | Bone Support Ab | A new bone substitute composition |
SE0302983D0 (sv) * | 2003-11-11 | 2003-11-11 | Bone Support Ab | Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed |
SE527528C2 (sv) | 2004-06-22 | 2006-04-04 | Bone Support Ab | Anordning för framställning av härdbar massa samt användning av anordningen |
EA011516B1 (ru) | 2005-01-13 | 2009-04-28 | Синвеншен Аг | Композиционный материал и способ его изготовления |
AU2008206953A1 (en) * | 2007-01-19 | 2008-07-24 | Cinvention Ag | Porous, non-degradable implant made by powder molding |
US20080206862A1 (en) * | 2007-02-28 | 2008-08-28 | Cinvention Ag | High surface cultivation system bag |
US7955234B1 (en) | 2007-02-28 | 2011-06-07 | Pursley Michael G | Exercise device and method |
EP2126040A1 (en) * | 2007-02-28 | 2009-12-02 | Cinvention Ag | High surface cultivation system |
EP2093206A1 (en) | 2008-02-20 | 2009-08-26 | BRACCO IMAGING S.p.A. | Process for the iodination of aromatic compounds |
KR101098553B1 (ko) * | 2008-04-30 | 2011-12-26 | 주식회사 엘지생명과학 | 이오프로마이드의 신규한 제조방법 |
US8624061B2 (en) * | 2008-11-18 | 2014-01-07 | Bracco Imaging S.P.A. | Process for the preparation of iodinated contrast agent |
US20110256068A1 (en) | 2009-01-09 | 2011-10-20 | Wistand Lars-Goeran | Contrast media compositions |
EP2230227A1 (en) * | 2009-03-20 | 2010-09-22 | Bracco Imaging S.p.A | Process for the preparation of triiodinated carboxylic aromatic derivatives |
EP2243767A1 (en) * | 2009-04-21 | 2010-10-27 | Bracco Imaging S.p.A | Process for the iodination of aromatic compounds |
DK2451994T3 (da) | 2009-07-07 | 2014-01-20 | Bracco Imaging Spa | Fremgangsmåde til fremstilling af et ioderende middel |
US9180137B2 (en) | 2010-02-09 | 2015-11-10 | Bone Support Ab | Preparation of bone cement compositions |
PT105770B (pt) * | 2011-06-24 | 2013-07-08 | Hovione Farmaciencia S A | Novo intermediário e seu uso na preparação de agente de contrate triiodado |
EP2931696B1 (en) | 2012-12-11 | 2018-08-22 | Bracco Imaging S.p.A | Continuous process for the preparation of (s)-2-acetyloxypropionic acid |
PT2958603T (pt) | 2013-02-20 | 2018-06-06 | Bone Support Ab | Endurecimento melhorado de substituto ósseo endurecível |
LT3066071T (lt) * | 2013-11-05 | 2018-09-10 | Bracco Imaging S.P.A. | Jopamidolio gamybos būdas |
CA2949433C (en) | 2014-06-10 | 2022-05-03 | Bracco Imaging Spa | Method for the preparation of (s)-2-acetyloxypropionic acid and derivatives thereof |
CN104230731B (zh) * | 2014-09-24 | 2016-01-20 | 武汉理工大学 | 造影剂中间体三碘异酞酰氯的制备方法 |
PT108524B (pt) | 2015-06-02 | 2017-12-15 | Hovione Farmaciência S A | Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos |
CN105461581A (zh) * | 2015-11-17 | 2016-04-06 | 浙江海洲制药有限公司 | 碘帕醇杂质a和杂质b的合成方法 |
CN107778191A (zh) * | 2016-08-26 | 2018-03-09 | 正大天晴药业集团股份有限公司 | 一种碘普罗胺及其中间体的制备方法 |
WO2018104228A1 (en) | 2016-12-05 | 2018-06-14 | Bracco Imaging Spa | Mechanochemical synthesis of radiographic agents intermediates |
JP7132252B2 (ja) | 2017-06-07 | 2022-09-06 | ブラッコ・イメージング・ソシエタ・ペル・アチオニ | 水溶液からのヨウ素の回収方法 |
WO2022200247A1 (en) | 2021-03-22 | 2022-09-29 | Bracco Imaging Spa | Industrial synthesis of serinol |
WO2023117667A1 (en) | 2021-12-20 | 2023-06-29 | Bracco Imaging Spa | Process for the preparation of 2,4,6-triiodoisophthalic bisamides |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL34803A (en) * | 1969-06-27 | 1975-03-13 | Nyegaard & Co As | N-hydroxyalkyl substituted benzamides and iodo methanesulfonamide and radiological compositions containing them |
DE2124904C3 (de) * | 1971-05-15 | 1980-09-18 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Hydroxy- und Alkoxyacetamido-trijodbenzoesäuren, deren Salze mit physiologisch verträglichen Basen, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Röntgenkontrastmittel |
BE788054A (fr) * | 1971-08-26 | 1973-02-26 | Bracco Ind Chimica Spa | Nouvel agent de contraste radiographique et procede pour le preparer |
CH583562A5 (ko) * | 1973-07-17 | 1977-01-14 | Bracco Ind Chimica Spa | |
CH576256A5 (ko) * | 1973-07-17 | 1976-06-15 | Bracco Ind Chimica Spa |
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1974
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