CH593994A5 - Antibiotic kanamycin A deriv - ie 1-(L-(-)-gamma-amino-alpha-hydroxy-butyril)-kanamycine A, prepd. by selective substn of kanamycine A - Google Patents

Antibiotic kanamycin A deriv - ie 1-(L-(-)-gamma-amino-alpha-hydroxy-butyril)-kanamycine A, prepd. by selective substn of kanamycine A

Info

Publication number
CH593994A5
CH593994A5 CH171774A CH171774A CH593994A5 CH 593994 A5 CH593994 A5 CH 593994A5 CH 171774 A CH171774 A CH 171774A CH 171774 A CH171774 A CH 171774A CH 593994 A5 CH593994 A5 CH 593994A5
Authority
CH
Switzerland
Prior art keywords
compound
kanamycin
solvent
temperature
water
Prior art date
Application number
CH171774A
Other languages
German (de)
English (en)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CH593994A5 publication Critical patent/CH593994A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH171774A 1973-02-07 1974-02-07 Antibiotic kanamycin A deriv - ie 1-(L-(-)-gamma-amino-alpha-hydroxy-butyril)-kanamycine A, prepd. by selective substn of kanamycine A CH593994A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33037773A 1973-02-07 1973-02-07

Publications (1)

Publication Number Publication Date
CH593994A5 true CH593994A5 (en) 1977-12-30

Family

ID=23289488

Family Applications (1)

Application Number Title Priority Date Filing Date
CH171774A CH593994A5 (en) 1973-02-07 1974-02-07 Antibiotic kanamycin A deriv - ie 1-(L-(-)-gamma-amino-alpha-hydroxy-butyril)-kanamycine A, prepd. by selective substn of kanamycine A

Country Status (10)

Country Link
JP (1) JPS575797B2 (enrdf_load_stackoverflow)
CA (1) CA1021329A (enrdf_load_stackoverflow)
CH (1) CH593994A5 (enrdf_load_stackoverflow)
DK (1) DK141910B (enrdf_load_stackoverflow)
FI (1) FI58134C (enrdf_load_stackoverflow)
HU (1) HU170378B (enrdf_load_stackoverflow)
NL (1) NL182962C (enrdf_load_stackoverflow)
SE (1) SE417971B (enrdf_load_stackoverflow)
SU (1) SU667142A3 (enrdf_load_stackoverflow)
YU (1) YU30674A (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5342038B2 (enrdf_load_stackoverflow) * 1973-11-19 1978-11-08
JPS5910360B2 (ja) * 1975-01-24 1984-03-08 萬有製薬株式会社 １−Ｎ−〔Ｌ−（一）−γ−アミノ−α−ヒドロキシブチリル〕−カナマイシン誘導体の改良された製造法
IT1139844B (it) * 1981-11-25 1986-09-24 Corvi Mora Paolo Processo per la preparazione di amikacina

Also Published As

Publication number Publication date
SE417971B (sv) 1981-04-27
YU30674A (en) 1982-02-28
DK141910B (da) 1980-07-14
SU667142A3 (ru) 1979-06-05
FI58134C (fi) 1980-12-10
NL7401517A (enrdf_load_stackoverflow) 1974-08-09
JPS575797B2 (enrdf_load_stackoverflow) 1982-02-01
FI58134B (fi) 1980-08-29
NL182962C (nl) 1988-06-16
HU170378B (enrdf_load_stackoverflow) 1977-06-28
DK141910C (enrdf_load_stackoverflow) 1980-11-24
NL182962B (nl) 1988-01-18
CA1021329A (en) 1977-11-22
JPS49102644A (enrdf_load_stackoverflow) 1974-09-27

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