CA1021329A - PROCESS FOR THE PREPARATION OF 1-(L-(-)-.gamma.-AMINO-.alpha.-HYDROXYBUTYRYL)-KANAMYCIN A - Google Patents

PROCESS FOR THE PREPARATION OF 1-(L-(-)-.gamma.-AMINO-.alpha.-HYDROXYBUTYRYL)-KANAMYCIN A

Info

Publication number
CA1021329A
CA1021329A CA191,868A CA191868A CA1021329A CA 1021329 A CA1021329 A CA 1021329A CA 191868 A CA191868 A CA 191868A CA 1021329 A CA1021329 A CA 1021329A
Authority
CA
Canada
Prior art keywords
hydroxybutyryl
kanamycin
gamma
alpha
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA191,868A
Other languages
English (en)
Other versions
CA191868S (en
Inventor
John G. Keil
Richard H. Schreiber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Canada Inc
Original Assignee
Bristol Myers Canada Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Canada Ltd filed Critical Bristol Myers Canada Ltd
Application granted granted Critical
Publication of CA1021329A publication Critical patent/CA1021329A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA191,868A 1973-02-07 1974-02-06 PROCESS FOR THE PREPARATION OF 1-(L-(-)-.gamma.-AMINO-.alpha.-HYDROXYBUTYRYL)-KANAMYCIN A Expired CA1021329A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33037773A 1973-02-07 1973-02-07

Publications (1)

Publication Number Publication Date
CA1021329A true CA1021329A (en) 1977-11-22

Family

ID=23289488

Family Applications (1)

Application Number Title Priority Date Filing Date
CA191,868A Expired CA1021329A (en) 1973-02-07 1974-02-06 PROCESS FOR THE PREPARATION OF 1-(L-(-)-.gamma.-AMINO-.alpha.-HYDROXYBUTYRYL)-KANAMYCIN A

Country Status (10)

Country Link
JP (1) JPS575797B2 (enrdf_load_stackoverflow)
CA (1) CA1021329A (enrdf_load_stackoverflow)
CH (1) CH593994A5 (enrdf_load_stackoverflow)
DK (1) DK141910B (enrdf_load_stackoverflow)
FI (1) FI58134C (enrdf_load_stackoverflow)
HU (1) HU170378B (enrdf_load_stackoverflow)
NL (1) NL182962C (enrdf_load_stackoverflow)
SE (1) SE417971B (enrdf_load_stackoverflow)
SU (1) SU667142A3 (enrdf_load_stackoverflow)
YU (1) YU30674A (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5342038B2 (enrdf_load_stackoverflow) * 1973-11-19 1978-11-08
JPS5910360B2 (ja) * 1975-01-24 1984-03-08 萬有製薬株式会社 １−Ｎ−〔Ｌ−（一）−γ−アミノ−α−ヒドロキシブチリル〕−カナマイシン誘導体の改良された製造法
IT1139844B (it) * 1981-11-25 1986-09-24 Corvi Mora Paolo Processo per la preparazione di amikacina

Also Published As

Publication number Publication date
SE417971B (sv) 1981-04-27
YU30674A (en) 1982-02-28
CH593994A5 (en) 1977-12-30
DK141910B (da) 1980-07-14
SU667142A3 (ru) 1979-06-05
FI58134C (fi) 1980-12-10
NL7401517A (enrdf_load_stackoverflow) 1974-08-09
JPS575797B2 (enrdf_load_stackoverflow) 1982-02-01
FI58134B (fi) 1980-08-29
NL182962C (nl) 1988-06-16
HU170378B (enrdf_load_stackoverflow) 1977-06-28
DK141910C (enrdf_load_stackoverflow) 1980-11-24
NL182962B (nl) 1988-01-18
JPS49102644A (enrdf_load_stackoverflow) 1974-09-27

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