CA993897A - "4-(4-biphenyl)-1-butanol" - Google Patents

"4-(4-biphenyl)-1-butanol"

Info

Publication number
CA993897A
CA993897A CA153,847A CA153847A CA993897A CA 993897 A CA993897 A CA 993897A CA 153847 A CA153847 A CA 153847A CA 993897 A CA993897 A CA 993897A
Authority
CA
Canada
Prior art keywords
biphenyl
butanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA153,847A
Other languages
English (en)
Other versions
CA153847S (en
Inventor
Gunther Engelhardt
Ernst Seeger
Wolfhard Engel
Helmut Teufel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Application granted granted Critical
Publication of CA993897A publication Critical patent/CA993897A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/10—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
    • C07C29/103—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes of cyclic ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C07C29/149—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/60—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by elimination of -OH groups, e.g. by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • C07C33/24—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part polycyclic without condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/26—Polyhydroxylic alcohols containing only six-membered aromatic rings as cyclic part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA153,847A 1971-10-15 1972-10-13 "4-(4-biphenyl)-1-butanol" Expired CA993897A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2151312A DE2151312C3 (de) 1971-10-15 1971-10-15 4- (4-Biphen ylyl) -l-butanol

Publications (1)

Publication Number Publication Date
CA993897A true CA993897A (en) 1976-07-27

Family

ID=5822378

Family Applications (1)

Application Number Title Priority Date Filing Date
CA153,847A Expired CA993897A (en) 1971-10-15 1972-10-13 "4-(4-biphenyl)-1-butanol"

Country Status (28)

Country Link
US (1) US3801654A (no)
JP (3) JPS5320031B2 (no)
AT (7) AT321897B (no)
AU (1) AU469279B2 (no)
BE (1) BE790086A (no)
BG (5) BG20777A3 (no)
CA (1) CA993897A (no)
CH (4) CH590185A5 (no)
CS (7) CS160613B2 (no)
DD (1) DD103233A5 (no)
DE (1) DE2151312C3 (no)
DK (1) DK129573B (no)
ES (5) ES407583A1 (no)
FI (1) FI55984C (no)
FR (1) FR2157860B1 (no)
GB (1) GB1361574A (no)
HU (1) HU164696B (no)
IE (1) IE36775B1 (no)
IL (1) IL40571A (no)
NL (1) NL7213927A (no)
NO (1) NO136092C (no)
PH (1) PH13645A (no)
PL (4) PL91408B1 (no)
RO (8) RO70567A (no)
SE (2) SE399417B (no)
SU (7) SU471710A3 (no)
YU (5) YU255972A (no)
ZA (1) ZA727320B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053639A (en) * 1964-01-24 1977-10-11 The Boots Company Limited Therapeutically active phenylalkane derivatives
BE790085A (fr) * 1971-10-15 1973-04-13 Thomae Gmbh Dr K Nouveaux 4-(4-biphenylyl)-butanols
DE2240440A1 (de) * 1972-08-17 1974-02-28 Thomae Gmbh Dr K Neue (4-biphenylyl)-alkohole und verfahren zu ihrer herstellung
DE2240438A1 (de) * 1972-08-17 1974-02-28 Thomae Gmbh Dr K Neue 2-(4-biphenylyl)-tetrahydrofurane und verfahren zu ihrer herstellung
DE2341506A1 (de) * 1973-08-16 1975-02-27 Thomae Gmbh Dr K Neue biphenylderivate und verfahren zu ihrer herstellung
DE2528958A1 (de) * 1975-06-28 1977-01-13 Merck Patent Gmbh Araliphatische dihalogenverbindungen und verfahren zu ihrer herstellung
DE2708520A1 (de) * 1977-02-26 1978-08-31 Thomae Gmbh Dr K Neue arzneimittelkombinationen und verfahren zu ihrer herstellung
DE3001303A1 (de) * 1980-01-16 1981-07-23 Basf Ag, 6700 Ludwigshafen Optisch aktive phenylpropan-derivate, ihre herstellung und verwendung
AT399471B (de) * 1993-06-04 1995-05-26 Ifw Manfred Otte Ges M B H & C Spritzgiessform

Also Published As

Publication number Publication date
IE36775L (en) 1973-04-15
CS160611B2 (no) 1975-03-28
AU469279B2 (en) 1976-02-12
BG20560A3 (bg) 1975-12-05
ZA727320B (en) 1974-06-26
SU474968A3 (ru) 1975-06-25
AU4774872A (en) 1974-04-26
RO70059A (ro) 1980-03-15
RO71244A (ro) 1982-07-06
YU197279A (en) 1982-06-18
HU164696B (no) 1974-03-28
YU197179A (en) 1982-06-18
JPS5387341A (en) 1978-08-01
IE36775B1 (en) 1977-02-16
FI55984B (fi) 1979-07-31
SU471710A3 (ru) 1975-05-25
CS160609B2 (no) 1975-03-28
PL91407B1 (no) 1977-02-28
US3801654A (en) 1974-04-02
DK129573C (no) 1975-03-24
DK129573B (da) 1974-10-28
FR2157860B1 (no) 1975-10-31
SE399417B (sv) 1978-02-13
JPS5515448B2 (no) 1980-04-23
IL40571A0 (en) 1972-12-29
CH599082A5 (no) 1978-05-12
SU464105A3 (ru) 1975-03-15
JPS5320031B2 (no) 1978-06-24
CH575358A5 (no) 1976-05-14
BG20777A3 (bg) 1975-12-20
SU496714A3 (ru) 1975-12-25
NO136092B (no) 1977-04-12
DE2151312C3 (de) 1975-07-31
CS160610B2 (no) 1975-03-28
IL40571A (en) 1975-10-15
DD103233A5 (no) 1974-01-12
SU496713A3 (ru) 1975-12-25
CS160613B2 (no) 1975-03-28
SU464106A3 (ru) 1975-03-15
GB1361574A (en) 1974-07-30
RO70567A (ro) 1981-07-30
ES415241A1 (es) 1976-06-16
JPS5387342A (en) 1978-08-01
RO71306A (ro) 1981-08-17
CS160615B2 (no) 1975-03-28
AT321897B (de) 1975-04-25
RO70058A (ro) 1982-09-09
PL91408B1 (no) 1977-02-28
YU255972A (en) 1982-06-18
AT321899B (de) 1975-04-25
NL7213927A (no) 1973-04-17
RO69378A (ro) 1981-04-20
AT315823B (de) 1974-06-10
AT321901B (de) 1975-04-25
JPS4861459A (no) 1973-08-28
JPS5542054B2 (no) 1980-10-28
DE2151312A1 (de) 1973-04-19
BG20332A3 (bg) 1975-11-05
ES407583A1 (es) 1975-11-01
PL83601B1 (no) 1975-12-31
SU453823A3 (ru) 1974-12-15
ES415243A1 (es) 1976-11-01
AT321900B (de) 1975-04-25
FI55984C (fi) 1979-11-12
YU197479A (en) 1982-06-18
YU197379A (en) 1982-06-18
PH13645A (en) 1980-08-18
NO136092C (no) 1977-07-20
PL91409B1 (no) 1977-02-28
ES415244A1 (es) 1976-11-01
CH590185A5 (no) 1977-07-29
CS160612B2 (no) 1975-03-28
ATA573873A (de) 1975-04-15
SE7600800L (sv) 1976-01-26
RO71307A (ro) 1982-03-24
AT321898B (de) 1975-04-25
CS160614B2 (no) 1975-03-28
RO70060A (ro) 1981-06-30
DE2151312B2 (no) 1974-11-28
FR2157860A1 (no) 1973-06-08
BE790086A (fr) 1973-04-13
BG20333A3 (bg) 1975-11-05
CH589575A5 (no) 1977-07-15
BG19586A3 (bg) 1975-06-25
AT327177B (de) 1976-01-26
ES415242A1 (es) 1976-06-16

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