CA3238440A1 - Dimethyltryptamine analogues as nitric oxide delivery drugs - Google Patents

Dimethyltryptamine analogues as nitric oxide delivery drugs Download PDF

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Publication number
CA3238440A1
CA3238440A1 CA3238440A CA3238440A CA3238440A1 CA 3238440 A1 CA3238440 A1 CA 3238440A1 CA 3238440 A CA3238440 A CA 3238440A CA 3238440 A CA3238440 A CA 3238440A CA 3238440 A1 CA3238440 A1 CA 3238440A1
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Prior art keywords
formula
compounds
compound
alkyl
cr7r7
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CA3238440A
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English (en)
French (fr)
Inventor
Glenn Short
Robert B. Perni
Tanweer Khan
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Atai Therapeutics Inc
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Individual
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Addiction (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3238440A 2021-12-30 2022-12-28 Dimethyltryptamine analogues as nitric oxide delivery drugs Pending CA3238440A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163295199P 2021-12-30 2021-12-30
US63/295,199 2021-12-30
PCT/US2022/082465 WO2023129956A2 (en) 2021-12-30 2022-12-28 Dimethyltryptamine analogues as nitric oxide delivery drugs

Publications (1)

Publication Number Publication Date
CA3238440A1 true CA3238440A1 (en) 2023-07-06

Family

ID=87000269

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3238440A Pending CA3238440A1 (en) 2021-12-30 2022-12-28 Dimethyltryptamine analogues as nitric oxide delivery drugs

Country Status (6)

Country Link
US (2) US12012381B2 (https=)
EP (1) EP4457214A4 (https=)
JP (1) JP2024545787A (https=)
AU (1) AU2022425541A1 (https=)
CA (1) CA3238440A1 (https=)
WO (1) WO2023129956A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
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