JP2024545787A - 一酸化窒素送達剤としてのジメチルトリプタミン類似体 - Google Patents

一酸化窒素送達剤としてのジメチルトリプタミン類似体 Download PDF

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JP2024545787A
JP2024545787A JP2024539472A JP2024539472A JP2024545787A JP 2024545787 A JP2024545787 A JP 2024545787A JP 2024539472 A JP2024539472 A JP 2024539472A JP 2024539472 A JP2024539472 A JP 2024539472A JP 2024545787 A JP2024545787 A JP 2024545787A
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absent
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JP2024545787A5 (https=
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グレン ショート,
ロバート ビー. ペルニ,
タンヴェア カーン,
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Atai Therapeutics Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Addiction (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2024539472A 2021-12-30 2022-12-28 一酸化窒素送達剤としてのジメチルトリプタミン類似体 Pending JP2024545787A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163295199P 2021-12-30 2021-12-30
US63/295,199 2021-12-30
PCT/US2022/082465 WO2023129956A2 (en) 2021-12-30 2022-12-28 Dimethyltryptamine analogues as nitric oxide delivery drugs

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JP2024545787A true JP2024545787A (ja) 2024-12-11
JP2024545787A5 JP2024545787A5 (https=) 2026-01-09

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US (2) US12012381B2 (https=)
EP (1) EP4457214A4 (https=)
JP (1) JP2024545787A (https=)
AU (1) AU2022425541A1 (https=)
CA (1) CA3238440A1 (https=)
WO (1) WO2023129956A2 (https=)

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* Cited by examiner, † Cited by third party
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EP4584247A2 (en) * 2022-09-06 2025-07-16 ATAI Therapeutics, Inc. Heteroatom substituted cyclic and alkyl amines as activators of serotonin receptors

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