CA3083097A1 - Reducing junction epitope presentation for neoantigens - Google Patents
Reducing junction epitope presentation for neoantigensInfo
- Publication number
- CA3083097A1 CA3083097A1 CA3083097A CA3083097A CA3083097A1 CA 3083097 A1 CA3083097 A1 CA 3083097A1 CA 3083097 A CA3083097 A CA 3083097A CA 3083097 A CA3083097 A CA 3083097A CA 3083097 A1 CA3083097 A1 CA 3083097A1
- Authority
- CA
- Canada
- Prior art keywords
- sequence
- epitopes
- presentation
- therapeutic
- cassette
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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| WO2016128060A1 (en) | 2015-02-12 | 2016-08-18 | Biontech Ag | Predicting t cell epitopes useful for vaccination |
| EP3389630B1 (en) | 2015-12-16 | 2023-11-08 | Gritstone bio, Inc. | Neoantigen identification, manufacture, and use |
| WO2017194170A1 (en) | 2016-05-13 | 2017-11-16 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of proteins or protein fragments for immunotherapy |
| WO2018224166A1 (en) | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| JP7227237B2 (ja) | 2017-10-10 | 2023-02-21 | グリットストーン バイオ インコーポレイテッド | ホットスポットを利用した新生抗原の特定 |
| CN111630602A (zh) | 2017-11-22 | 2020-09-04 | 磨石肿瘤生物技术公司 | 减少新抗原的接合表位呈递 |
| CA3124905A1 (en) | 2019-01-03 | 2020-07-09 | Jens KRINGELUM | Vaccines targeting neoepitopes |
| EP3937973A1 (en) | 2019-03-11 | 2022-01-19 | Evaxion Biotech A/S | Nucleic acid vaccination using neo-epitope encoding constructs |
| CN120775062A (zh) | 2019-07-16 | 2025-10-14 | 吉利德科学公司 | Hiv疫苗及其制备和使用方法 |
| WO2021048400A1 (en) | 2019-09-13 | 2021-03-18 | Evaxion Biotech Aps | Method for identifying t-cell epitopes |
| WO2021123232A1 (en) | 2019-12-18 | 2021-06-24 | Evaxion Biotech Aps | Nucleic acid vaccination using neo-epitope encoding constructs |
| EP4116436A4 (en) * | 2020-01-07 | 2024-01-31 | Korea Advanced Institute of Science and Technology | METHOD AND SYSTEM FOR SCREENING NEOANTIGENS AND USES THEREOF |
| WO2021204911A1 (en) | 2020-04-07 | 2021-10-14 | Evaxion Biotech A/S | Neoepitope immunotherapy with apc targeting unit |
| EP4181949A1 (en) | 2020-07-14 | 2023-05-24 | Evaxion Biotech A/S | Apc targeting units for immunotherapy |
| CA3202382A1 (en) * | 2020-12-18 | 2022-06-23 | Yeda Research And Development Co. Ltd. | Compositions for use in the treatment of chd2 haploinsufficiency and methods of identifying same |
| WO2022155258A1 (en) | 2021-01-14 | 2022-07-21 | Gilead Sciences, Inc. | Hiv vaccines and methods of using |
| WO2022229966A1 (en) | 2021-04-29 | 2022-11-03 | Yeda Research And Development Co. Ltd. | T cell receptors directed against ras-derived recurrent neoantigens and methods of identifying same |
| KR102475794B1 (ko) * | 2022-08-23 | 2022-12-08 | 주식회사 테라젠바이오 | 합성 긴 펩타이드의 면역원성 예측 장치, 면역원성 예측 방법 및 컴퓨터 프로그램 |
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- 2018-11-21 EP EP18880880.2A patent/EP3714275A4/en active Pending
- 2018-11-21 US US16/766,627 patent/US11885815B2/en active Active
- 2018-11-21 IL IL274799A patent/IL274799B2/en unknown
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2023
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| IL274799B2 (en) | 2025-05-01 |
| KR20200090855A (ko) | 2020-07-29 |
| US11885815B2 (en) | 2024-01-30 |
| CN111630602A (zh) | 2020-09-04 |
| AU2018373154A1 (en) | 2020-07-02 |
| IL274799A (en) | 2020-07-30 |
| JP2024012365A (ja) | 2024-01-30 |
| US20240361335A1 (en) | 2024-10-31 |
| JP7755628B2 (ja) | 2025-10-16 |
| EP3714275A1 (en) | 2020-09-30 |
| AU2025259935A1 (en) | 2025-11-20 |
| US20210011026A1 (en) | 2021-01-14 |
| IL274799B1 (en) | 2025-01-01 |
| JP2021503897A (ja) | 2021-02-15 |
| JP2025175055A (ja) | 2025-11-28 |
| WO2019104203A1 (en) | 2019-05-31 |
| AU2018373154B2 (en) | 2025-08-07 |
| EP3714275A4 (en) | 2021-10-27 |
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