CA3040919A1 - Substituted pyridinone-containing tricyclic compounds, and methods using same - Google Patents

Substituted pyridinone-containing tricyclic compounds, and methods using same Download PDF

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Publication number
CA3040919A1
CA3040919A1 CA3040919A CA3040919A CA3040919A1 CA 3040919 A1 CA3040919 A1 CA 3040919A1 CA 3040919 A CA3040919 A CA 3040919A CA 3040919 A CA3040919 A CA 3040919A CA 3040919 A1 CA3040919 A1 CA 3040919A1
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group
alkyl
compound
optionally substituted
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French (fr)
Inventor
Dimitar B. Gotchev
Bruce D. Dorsey
Ramesh Kakarla
Yingzhi Bi
Duyan Nguyen
Shuai Chen
Mark Christopher Wood
Lauren Danielle Bailey
Richard James Holland
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Arbutus Biopharma Corp
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Arbutus Biopharma Corp
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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CN108727378A (zh) * 2017-04-19 2018-11-02 银杏树药业(苏州)有限公司 新型异喹啉类化合物及其医药用途
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CN111217811B (zh) * 2018-11-26 2024-01-16 广东东阳光药业股份有限公司 稠合三环类化合物及其在药物中的应用

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TW201823232A (zh) 2018-07-01
CN110114071A (zh) 2019-08-09
US20190314347A1 (en) 2019-10-17
WO2018085619A1 (en) 2018-05-11
US10821103B2 (en) 2020-11-03
AU2017353986A1 (en) 2019-04-18
SG11201902944TA (en) 2019-05-30
KR102522060B1 (ko) 2023-04-14
US11013726B2 (en) 2021-05-25
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