CA3036306C - Ophthalmic compositions comprising ciclosporin - Google Patents

Ophthalmic compositions comprising ciclosporin Download PDF

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Publication number
CA3036306C
CA3036306C CA3036306A CA3036306A CA3036306C CA 3036306 C CA3036306 C CA 3036306C CA 3036306 A CA3036306 A CA 3036306A CA 3036306 A CA3036306 A CA 3036306A CA 3036306 C CA3036306 C CA 3036306C
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CA
Canada
Prior art keywords
ciclosporin
composition
water content
less
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3036306A
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English (en)
French (fr)
Other versions
CA3036306A1 (en
Inventor
Frank Loscher
Ralf Grillenberger
Johan Engblom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novaliq GmbH
Original Assignee
Novaliq GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of CA3036306A1 publication Critical patent/CA3036306A1/en
Application granted granted Critical
Publication of CA3036306C publication Critical patent/CA3036306C/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CA3036306A 2016-09-23 2017-09-22 Ophthalmic compositions comprising ciclosporin Active CA3036306C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16190431 2016-09-23
EP16190431.3 2016-09-23
PCT/EP2017/074079 WO2018055101A1 (en) 2016-09-23 2017-09-22 Ophthalmic compositions comprising ciclosporin

Publications (2)

Publication Number Publication Date
CA3036306A1 CA3036306A1 (en) 2018-03-29
CA3036306C true CA3036306C (en) 2024-05-14

Family

ID=56990364

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3036306A Active CA3036306C (en) 2016-09-23 2017-09-22 Ophthalmic compositions comprising ciclosporin

Country Status (10)

Country Link
US (3) US10813976B2 (enExample)
EP (1) EP3515467B1 (enExample)
JP (1) JP6869336B2 (enExample)
KR (1) KR20190057338A (enExample)
CN (1) CN109906085B (enExample)
AU (1) AU2017329983B2 (enExample)
CA (1) CA3036306C (enExample)
ES (1) ES2965677T3 (enExample)
MX (1) MX2019003364A (enExample)
WO (1) WO2018055101A1 (enExample)

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CN110650734B (zh) 2017-05-12 2024-11-15 诺瓦利克有限责任公司 治疗与隐形眼镜有关病症的包含半氟化烷烃的药物组合物
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JP2021522219A (ja) 2018-04-27 2021-08-30 ノバリック ゲーエムベーハー 緑内障の治療のためのタフルプロストを含む眼科用組成物
WO2020074697A1 (en) 2018-10-12 2020-04-16 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease
WO2020165132A1 (en) 2019-02-13 2020-08-20 Novaliq Gmbh Compositions and methods for the treatment of ocular neovascularization
WO2021044045A1 (en) 2019-09-06 2021-03-11 Novaliq Gmbh Ophthalmic composition for the treatment of uveitis
EP3861857A1 (en) * 2020-02-07 2021-08-11 Novaliq GmbH Antiparasitic compositions

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US11400132B2 (en) 2022-08-02
ES2965677T3 (es) 2024-04-16
US20220354926A1 (en) 2022-11-10
EP3515467C0 (en) 2023-11-29
AU2017329983A1 (en) 2019-04-04
MX2019003364A (es) 2019-10-02
JP6869336B2 (ja) 2021-05-12
EP3515467B1 (en) 2023-11-29
JP2019529457A (ja) 2019-10-17
US10813976B2 (en) 2020-10-27
AU2017329983B2 (en) 2022-05-05
EP3515467A1 (en) 2019-07-31
CA3036306A1 (en) 2018-03-29
KR20190057338A (ko) 2019-05-28
WO2018055101A1 (en) 2018-03-29
CN109906085B (zh) 2024-03-08
US20210023166A1 (en) 2021-01-28
US20200023035A1 (en) 2020-01-23

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