CA2982532C - T cell which expresses a gamma-delta t cell receptor (tcr) and a chimeric antigen receptor (car) - Google Patents
T cell which expresses a gamma-delta t cell receptor (tcr) and a chimeric antigen receptor (car) Download PDFInfo
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- CA2982532C CA2982532C CA2982532A CA2982532A CA2982532C CA 2982532 C CA2982532 C CA 2982532C CA 2982532 A CA2982532 A CA 2982532A CA 2982532 A CA2982532 A CA 2982532A CA 2982532 C CA2982532 C CA 2982532C
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| CN111801348A (zh) | 2018-02-09 | 2020-10-20 | 新加坡国立大学 | 活化性嵌合受体及其在自然杀伤细胞免疫疗法中的用途 |
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| KR20200138741A (ko) | 2018-04-02 | 2020-12-10 | 내셔널 유니버시티 오브 싱가포르 | 면역 세포에서 발현되는 막-결합 항-사이토카인 비-신호전달 결합제를 이용한 인간 사이토카인의 중화 |
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| CA3098128A1 (en) * | 2018-04-18 | 2019-10-24 | Ucl Business Ltd | Engineered regulatory t cell |
| CN108588023B (zh) * | 2018-05-09 | 2020-02-14 | 河北森朗生物科技有限公司 | 一种生产嵌合抗原受体修饰的γδT细胞的方法 |
| CN110577932A (zh) * | 2018-06-07 | 2019-12-17 | 亘喜生物科技（上海）有限公司 | 一种脐带血来源的嵌合抗原受体t细胞 |
| WO2019242632A1 (en) * | 2018-06-19 | 2019-12-26 | 1§1Nanjing Legend Biotech Co., Ltd. | Engineered cells and uses thereof |
| US20210238550A1 (en) | 2018-07-31 | 2021-08-05 | Thyas Co. Ltd. | METHOD FOR PRODUCING REGENERATED T CELL POPULATION VIA iPS CELLS |
| US12156888B2 (en) | 2018-08-07 | 2024-12-03 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | CAR T-cells for the treatment of bone metastatic cancer |
| DK3835415T3 (en) * | 2018-08-10 | 2025-01-02 | Univ Kyoto | Fremgangsmåde til fremstilling af cd3-positiv celle |
| JP7560882B2 (ja) | 2018-08-29 | 2024-10-03 | ナショナル ユニヴァーシティー オブ シンガポール | 遺伝子修飾免疫細胞の生存及び増加を特異的に刺激するための方法 |
| BR112021005184A8 (pt) * | 2018-09-19 | 2022-08-16 | Lava Therapeutics B V | Imunoglobulina cd1d de dupla ação |
| CN109234236A (zh) * | 2018-09-29 | 2019-01-18 | 吉林大学第医院 | 一种嵌合抗原受体γδT细胞的制备方法 |
| KR20210087458A (ko) * | 2018-10-01 | 2021-07-12 | 아디셋 바이오, 인크. | 고형 종양 치료를 위한 조작된 및 비-조작된 γδ-T 세포에 관한 조성물 및 방법 |
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| CN113508137B (zh) * | 2019-01-29 | 2024-12-20 | 上海交通大学 | 一种嵌合抗原受体及其应用 |
| US20220088074A1 (en) * | 2019-02-21 | 2022-03-24 | Regents Of The University Of Minnesota | Genetically modified gamma delta t cells and methods of making and using |
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| CN113939302A (zh) | 2019-06-14 | 2022-01-14 | 赛雅思株式会社 | 医药组合物 |
| US20220259281A1 (en) * | 2019-06-21 | 2022-08-18 | Shattuck Labs, Inc. | Chimeric protein expressing t-cells |
| GB201909283D0 (en) * | 2019-06-27 | 2019-08-14 | Cancer Research Tech Ltd | Fusion proteins with enzyme activity |
| CN110981972B (zh) * | 2019-12-25 | 2022-09-30 | 华夏源（上海）细胞基因工程股份有限公司 | 一种分泌双特异性抗体的嵌合抗原受体及其表达载体和应用 |
| WO2021176373A1 (en) * | 2020-03-03 | 2021-09-10 | Janssen Biotech, Inc. | ꝩδ T CELLS AND USES THEREOF |
| BR112022023371A2 (pt) | 2020-05-22 | 2022-12-20 | Chongqing Prec Biotech Co Ltd | Proteína de fusão para reversão do microambiente tumoral, vetor de expressão, célula imune, receptor de antígeno quimérico resistente à imunossupressão tumoral, sequência de ácido nucleico, método para preparar uma célula imune, composição farmacêutica, e, uso da composição farmacêutica |
| IL299886A (en) | 2020-07-17 | 2023-03-01 | Instil Bio Uk Ltd | Receptors that provide targeted costimulation for host cell therapy |
| US12012441B2 (en) | 2020-10-26 | 2024-06-18 | Neptune Biosciences Llc | Engineered human IL-21 cytokines and methods for using the same |
| EP4355340A4 (en) | 2021-06-16 | 2025-05-21 | Instil Bio, Inc. | RECEPTORS FOR TARGETED COSTIMULATION FOR ADOPTIVE CELL THERAPY |
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| CN113528455A (zh) * | 2021-07-19 | 2021-10-22 | 广州百暨基因科技有限公司 | 表达嵌合抗原受体的γδT细胞 |
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2015
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2016
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- 2016-04-29 HK HK18111473.3A patent/HK1252235A1/zh unknown
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| AU2016255611B2 (en) | 2021-08-05 |
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| IL255186A0 (en) | 2017-12-31 |
| ES3018558T3 (es) | 2025-05-16 |
| EP3288567B1 (en) | 2025-03-19 |
| ZA201706923B (en) | 2022-02-23 |
| EA201792042A1 (ru) | 2018-03-30 |
| GB201507368D0 (en) | 2015-06-17 |
| HK1252235A1 (zh) | 2019-05-24 |
| JP2018514204A (ja) | 2018-06-07 |
| US20180125890A1 (en) | 2018-05-10 |
| SG11201708402UA (en) | 2017-11-29 |
| CA2982532A1 (en) | 2016-11-03 |
| US12331316B2 (en) | 2025-06-17 |
| CN107771215A (zh) | 2018-03-06 |
| KR20180020140A (ko) | 2018-02-27 |
| US20220211756A1 (en) | 2022-07-07 |
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