CA2966060A1 - Soluble, stable, anti-inflammatory, proliferative, protective and mucoadhesive pharmaceutical compositions; use thereof for treating mucositis conditions and method for producingsame; base pharmaceutical composition for preparing the pharmaceutical compositions and method for producing same - Google Patents

Soluble, stable, anti-inflammatory, proliferative, protective and mucoadhesive pharmaceutical compositions; use thereof for treating mucositis conditions and method for producingsame; base pharmaceutical composition for preparing the pharmaceutical compositions and method for producing same Download PDF

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Publication number
CA2966060A1
CA2966060A1 CA2966060A CA2966060A CA2966060A1 CA 2966060 A1 CA2966060 A1 CA 2966060A1 CA 2966060 A CA2966060 A CA 2966060A CA 2966060 A CA2966060 A CA 2966060A CA 2966060 A1 CA2966060 A1 CA 2966060A1
Authority
CA
Canada
Prior art keywords
extract
pharmaceutical compositions
curcuminoids
poloxamer
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2966060A
Other languages
English (en)
French (fr)
Inventor
Marize Campos Valadares BOZINIS
Eliana Martins LIMA
Aline Carvalho BATISTA
Ricardo Neves MARRETO
Elismauro Francisco De Mendonca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FBM INDUSTRIA FARMACEUTICA LTDA
UNIVERSIDADE FEDERAL DE GOIAS - UFG
Original Assignee
FBM INDUSTRIA FARMACEUTICA LTDA
UNIVERSIDADE FEDERAL DE GOIAS - UFG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FBM INDUSTRIA FARMACEUTICA LTDA, UNIVERSIDADE FEDERAL DE GOIAS - UFG filed Critical FBM INDUSTRIA FARMACEUTICA LTDA
Publication of CA2966060A1 publication Critical patent/CA2966060A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2966060A 2014-10-27 2014-10-27 Soluble, stable, anti-inflammatory, proliferative, protective and mucoadhesive pharmaceutical compositions; use thereof for treating mucositis conditions and method for producingsame; base pharmaceutical composition for preparing the pharmaceutical compositions and method for producing same Abandoned CA2966060A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/BR2014/050002 WO2016065442A1 (pt) 2014-10-27 2014-10-27 Composições farmacêuticas antiinflamatórias, proliferativas, protetoras e mucoadesivas, solúveis e estáveis; seu uso no tratamento dos quadros de mucosite e processo de obtenção; composição farmacêutica de base para o preparo das composições farmacêuticas e seu processo de obtenção

Publications (1)

Publication Number Publication Date
CA2966060A1 true CA2966060A1 (en) 2016-05-06

Family

ID=55856293

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2966060A Abandoned CA2966060A1 (en) 2014-10-27 2014-10-27 Soluble, stable, anti-inflammatory, proliferative, protective and mucoadhesive pharmaceutical compositions; use thereof for treating mucositis conditions and method for producingsame; base pharmaceutical composition for preparing the pharmaceutical compositions and method for producing same

Country Status (6)

Country Link
US (1) US11007244B2 (cg-RX-API-DMAC7.html)
EP (1) EP3213760A4 (cg-RX-API-DMAC7.html)
JP (1) JP7020915B2 (cg-RX-API-DMAC7.html)
CA (1) CA2966060A1 (cg-RX-API-DMAC7.html)
RU (1) RU2017114569A (cg-RX-API-DMAC7.html)
WO (1) WO2016065442A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019203813A1 (en) * 2018-04-18 2019-10-24 Muhammed Majeed Compositions containing tetrahydrocurcuminoids for improvement of oral health and hygiene
CN111358927B (zh) * 2020-04-30 2021-09-07 深圳市宝安中医院(集团) 蒲姜药物组合物及其应用
CN112773887B (zh) * 2021-01-06 2023-05-23 温州医科大学 一种用于结肠黏膜修复的温敏凝胶
CN115919816B (zh) * 2022-09-27 2024-04-09 四川大学 姜黄素-四面体框架核酸载药系统在制备预防或治疗放射性口腔黏膜炎的药物中的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07330582A (ja) * 1994-01-31 1995-12-19 Takeda Chem Ind Ltd 直腸投与用組成物
KR100419132B1 (ko) * 2000-12-29 2004-02-18 조성근 위·장 점막 부착성과 증식성, 내산성, 내담즙성 및헬리코박터 파일로리, 대장균 0157:h7에 대한 항균성이우수한 락토바실러스 파라카제이 서브스패시즈 파라카제이csk 01
PT1363600E (pt) * 2001-02-15 2008-12-22 Access Pharma Inc Formulações líquidas para a prevenção e para o tratamento de doenças e distúrbios das mucosas
CN102176920B (zh) * 2008-11-17 2013-09-18 莱拉制药用品私营有限责任公司 姜黄素及其用于治疗眼科疾病的方法
AT509777B1 (de) * 2010-04-30 2012-03-15 Orphanidis Pharma Res Gmbh Adhesive retardformulierungen zur lokalen verabreichung von curcumin

Also Published As

Publication number Publication date
JP7020915B2 (ja) 2022-02-16
WO2016065442A1 (pt) 2016-05-06
US20170319642A1 (en) 2017-11-09
EP3213760A4 (en) 2018-06-20
RU2017114569A (ru) 2018-11-29
RU2017114569A3 (cg-RX-API-DMAC7.html) 2018-11-29
EP3213760A1 (en) 2017-09-06
US11007244B2 (en) 2021-05-18
JP2017533264A (ja) 2017-11-09

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20170427

FZDE Discontinued

Effective date: 20190919