JP7020915B2 - 抗炎症性、増殖性、保護性及び粘膜付着性の、可溶性且つ安定な医薬組成物、粘膜部位の状態を治療するためのその使用及び取得方法、並びに医薬組成物の調製のための基本医薬組成物及びその取得方法 - Google Patents

抗炎症性、増殖性、保護性及び粘膜付着性の、可溶性且つ安定な医薬組成物、粘膜部位の状態を治療するためのその使用及び取得方法、並びに医薬組成物の調製のための基本医薬組成物及びその取得方法 Download PDF

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JP7020915B2
JP7020915B2 JP2017541143A JP2017541143A JP7020915B2 JP 7020915 B2 JP7020915 B2 JP 7020915B2 JP 2017541143 A JP2017541143 A JP 2017541143A JP 2017541143 A JP2017541143 A JP 2017541143A JP 7020915 B2 JP7020915 B2 JP 7020915B2
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curcuminoids
mucositis
mixture
pharmaceutical compositions
inflammatory
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カンポス バラダレス ボズィニス，マリゼ
マルチンス リマ，エリアーナ
カルヴァーリョ バティスタ，アリーニ
ネベス マレト，リカルド
メンドンサ，エリスマウロ フランシスコ デ
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FBM INDUSTRIA FARMACEUTICA LTDA
UNIVERSIDADE FEDERAL DE GOIAS-UFG
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FBM INDUSTRIA FARMACEUTICA LTDA
UNIVERSIDADE FEDERAL DE GOIAS-UFG
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • Natural Medicines & Medicinal Plants (AREA)
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  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Plant Substances (AREA)
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JP2017541143A 2014-10-27 2014-10-27 抗炎症性、増殖性、保護性及び粘膜付着性の、可溶性且つ安定な医薬組成物、粘膜部位の状態を治療するためのその使用及び取得方法、並びに医薬組成物の調製のための基本医薬組成物及びその取得方法 Active JP7020915B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/BR2014/050002 WO2016065442A1 (pt) 2014-10-27 2014-10-27 Composições farmacêuticas antiinflamatórias, proliferativas, protetoras e mucoadesivas, solúveis e estáveis; seu uso no tratamento dos quadros de mucosite e processo de obtenção; composição farmacêutica de base para o preparo das composições farmacêuticas e seu processo de obtenção

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JP2017533264A JP2017533264A (ja) 2017-11-09
JP2017533264A5 JP2017533264A5 (cg-RX-API-DMAC7.html) 2017-12-21
JP7020915B2 true JP7020915B2 (ja) 2022-02-16

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US (1) US11007244B2 (cg-RX-API-DMAC7.html)
EP (1) EP3213760A4 (cg-RX-API-DMAC7.html)
JP (1) JP7020915B2 (cg-RX-API-DMAC7.html)
CA (1) CA2966060A1 (cg-RX-API-DMAC7.html)
RU (1) RU2017114569A (cg-RX-API-DMAC7.html)
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Publication number Priority date Publication date Assignee Title
WO2019203813A1 (en) * 2018-04-18 2019-10-24 Muhammed Majeed Compositions containing tetrahydrocurcuminoids for improvement of oral health and hygiene
CN111358927B (zh) * 2020-04-30 2021-09-07 深圳市宝安中医院（集团） 蒲姜药物组合物及其应用
CN112773887B (zh) * 2021-01-06 2023-05-23 温州医科大学 一种用于结肠黏膜修复的温敏凝胶
CN115919816B (zh) * 2022-09-27 2024-04-09 四川大学 姜黄素-四面体框架核酸载药系统在制备预防或治疗放射性口腔黏膜炎的药物中的用途

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Publication number Priority date Publication date Assignee Title
JPH07330582A (ja) * 1994-01-31 1995-12-19 Takeda Chem Ind Ltd 直腸投与用組成物
KR100419132B1 (ko) * 2000-12-29 2004-02-18 조성근 위·장 점막 부착성과 증식성, 내산성, 내담즙성 및헬리코박터 파일로리, 대장균 0157:ｈ7에 대한 항균성이우수한 락토바실러스 파라카제이 서브스패시즈 파라카제이ｃｓｋ 01
PT1363600E (pt) * 2001-02-15 2008-12-22 Access Pharma Inc Formulações líquidas para a prevenção e para o tratamento de doenças e distúrbios das mucosas
CN102176920B (zh) * 2008-11-17 2013-09-18 莱拉制药用品私营有限责任公司 姜黄素及其用于治疗眼科疾病的方法
AT509777B1 (de) * 2010-04-30 2012-03-15 Orphanidis Pharma Res Gmbh Adhesive retardformulierungen zur lokalen verabreichung von curcumin

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Ｃａｒｌａ Ｃａｒｏｌｉｎｅ Ｃ． Ｂａｓｔｏｓａ ｅｔ ａｌ．，ＥＦＥＩＴＯＳ ＤＡ ＣＯＭＢＩＮＡＣＡＯ ＭＵＣＯＡＤＥＳＩＶＡ ＤＥ ＢＩＤＥＮＳ ＰＩＬＯＳＡ Ｅ ＣＵＲＣＵＭＡ ＬＯＮＧＡ ＮＯ ＴＲＡＴＡＭＥＮＴＯ ＤＡ ＭＵＣＯＳＩＴＥ ＩＮＴＥＳＴＩＮＡＬ，Ｒｅｖｉｓｔａ ｄｅ Ｂｉｏｔｅｃｎｏｌｏｇｉａ ＆ Ｃｉｅｎｃｉａ，２０１３，Ｖｏｌ．２，Ｎｏ．１
Ｉｎｔ． Ｊ． Ｃｏｌｏｒｅｃｔａｌ Ｄｉｓ．，２０１２，Ｖｏｌ．２７，ｐｐ．８６９－８７８
Ｐａｕｌｏ Ｈｅｎｒｉｑｕｅ Ｍａｒｃｅｌｉｎｏ ｄｅ Ａｖｉｌａ， Ａｃａｏ ｄａ ｆｏｒｍｕｌａｃａｏ ｍｕｃｏａｄｅｓｉｖａ ｃｏｎｔｅｎｄｏ Ｂｉｄｅｎｓ ｐｉｌｏｓａ Ｌ （Ａｓｔｅｒａｃｅａｅ） ｓｏｂｒｅ ａ ｍｕｃｏｓｉｔｅ ｉｎｔｅｓｔｉｎａｌ ｉｎｄｕｚｉｄａ ｐｏｒ ５－ｆｌｕｏｒｏｕｒａｃｉｌ ｅｍ ｃａｍｕｎｄｏｎｇｏｓ ，ゴイアス州立大学大学院薬学修士論文，２０１３，ＵＲＬは以下，ｈｔｔｐｓ：／／ｒｅｐｏｓｉｔｏｒｉｏ．ｂｃ．ｕｆｇ．ｂｒ／ｔｅｄｅ／ｂｉｔｓｔｒｅａｍ／ｔｅｄｅ／５０５９／５／Ｄｉｓｓｅｒｔａ％ｃ３％ａ７％ｃ３％ａ３ｏ％２０－％２０Ｐａｕｌｏ％２０Ｈｅｎｒｉｑｕｅ％２０Ｍａｒｃｅｌｉｎｏ％２０ｄｅ％２０％ｃ３％８１ｖｉｌａ％２０－％２０２０１３．ｐｄｆ

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Publication number Publication date
WO2016065442A1 (pt) 2016-05-06
US20170319642A1 (en) 2017-11-09
CA2966060A1 (en) 2016-05-06
EP3213760A4 (en) 2018-06-20
RU2017114569A (ru) 2018-11-29
RU2017114569A3 (cg-RX-API-DMAC7.html) 2018-11-29
EP3213760A1 (en) 2017-09-06
US11007244B2 (en) 2021-05-18
JP2017533264A (ja) 2017-11-09

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