CA2928969C - Compositions and methods for ophthalmic and/or other applications - Google Patents

Compositions and methods for ophthalmic and/or other applications Download PDF

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Publication number
CA2928969C
CA2928969C CA2928969A CA2928969A CA2928969C CA 2928969 C CA2928969 C CA 2928969C CA 2928969 A CA2928969 A CA 2928969A CA 2928969 A CA2928969 A CA 2928969A CA 2928969 C CA2928969 C CA 2928969C
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CA
Canada
Prior art keywords
pharmaceutical composition
equal
less
loteprednol etabonate
coated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2928969A
Other languages
English (en)
French (fr)
Other versions
CA2928969A1 (en
Inventor
Alexey Popov
Elizabeth M. Enlow
Hongming Chen
James BOURASSA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Inc
Original Assignee
Kala Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kala Pharmaceuticals Inc filed Critical Kala Pharmaceuticals Inc
Priority to CA3135978A priority Critical patent/CA3135978A1/en
Publication of CA2928969A1 publication Critical patent/CA2928969A1/en
Application granted granted Critical
Publication of CA2928969C publication Critical patent/CA2928969C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2928969A 2013-11-02 2014-10-31 Compositions and methods for ophthalmic and/or other applications Active CA2928969C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3135978A CA3135978A1 (en) 2013-11-02 2014-10-31 Compositions and methods for ophthalmic and/or other applications

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/070,506 US9827191B2 (en) 2012-05-03 2013-11-02 Compositions and methods for ophthalmic and/or other applications
US14/070,506 2013-11-02
PCT/US2014/063373 WO2015066444A1 (en) 2013-11-02 2014-10-31 Compositions and methods for ophthalmic and/or other applications

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3135978A Division CA3135978A1 (en) 2013-11-02 2014-10-31 Compositions and methods for ophthalmic and/or other applications

Publications (2)

Publication Number Publication Date
CA2928969A1 CA2928969A1 (en) 2015-05-07
CA2928969C true CA2928969C (en) 2021-11-30

Family

ID=53005177

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2928969A Active CA2928969C (en) 2013-11-02 2014-10-31 Compositions and methods for ophthalmic and/or other applications
CA3135978A Pending CA3135978A1 (en) 2013-11-02 2014-10-31 Compositions and methods for ophthalmic and/or other applications

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3135978A Pending CA3135978A1 (en) 2013-11-02 2014-10-31 Compositions and methods for ophthalmic and/or other applications

Country Status (8)

Country Link
US (8) US9827191B2 (https=)
EP (1) EP3062796A4 (https=)
JP (3) JP6751669B2 (https=)
CN (3) CN105916509B (https=)
AU (1) AU2014342097B2 (https=)
CA (2) CA2928969C (https=)
MX (2) MX384021B (https=)
WO (1) WO2015066444A1 (https=)

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