ATE478656T1 - Biologisch abbaubare polymerzusammensetzungen, zusammensetzungen und damit in beziehung stehende verwendungen - Google Patents
Biologisch abbaubare polymerzusammensetzungen, zusammensetzungen und damit in beziehung stehende verwendungenInfo
- Publication number
- ATE478656T1 ATE478656T1 AT02756268T AT02756268T ATE478656T1 AT E478656 T1 ATE478656 T1 AT E478656T1 AT 02756268 T AT02756268 T AT 02756268T AT 02756268 T AT02756268 T AT 02756268T AT E478656 T1 ATE478656 T1 AT E478656T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- biodegradable polymer
- polymers
- related uses
- polymer compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 229920002988 biodegradable polymer Polymers 0.000 title abstract 2
- 239000004621 biodegradable polymer Substances 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000004005 microsphere Substances 0.000 abstract 1
- 239000002077 nanosphere Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyethers (AREA)
- Biological Depolymerization Polymers (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29972901P | 2001-06-22 | 2001-06-22 | |
| PCT/US2002/019772 WO2003000237A2 (en) | 2001-06-22 | 2002-06-21 | Biodegradable polymer coompositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE478656T1 true ATE478656T1 (de) | 2010-09-15 |
Family
ID=23156038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02756268T ATE478656T1 (de) | 2001-06-22 | 2002-06-21 | Biologisch abbaubare polymerzusammensetzungen, zusammensetzungen und damit in beziehung stehende verwendungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7163697B2 (de) |
| EP (1) | EP1406593B1 (de) |
| JP (1) | JP4758607B2 (de) |
| AT (1) | ATE478656T1 (de) |
| AU (1) | AU2002322289A1 (de) |
| DE (1) | DE60237449D1 (de) |
| WO (1) | WO2003000237A2 (de) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005510571A (ja) * | 2001-11-23 | 2005-04-21 | ラトガーズ, ザ ステート ユニバーシティー | ポリ無水物の改善された合成 |
| US7351749B2 (en) * | 2002-12-16 | 2008-04-01 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Process for manufacture of personal care products utilizing a concentrate water phase |
| US7662864B2 (en) * | 2003-06-04 | 2010-02-16 | Rutgers, The State University Of New Jersey | Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent |
| US20050196455A1 (en) * | 2003-10-27 | 2005-09-08 | Jianbing Chen | Suspension delivery system for the sustained and controlled local release of pharmaceuticals |
| JP2005206491A (ja) * | 2004-01-21 | 2005-08-04 | Medgel Corp | 肺気腫を治療するための経肺投与用製剤 |
| EP1713514B1 (de) * | 2004-01-28 | 2021-11-24 | Johns Hopkins University | Arzneimittel und genträgerteilchen, die sich schnell durch schleimhautbarrieren bewegen |
| EP1856179B1 (de) * | 2004-12-10 | 2013-05-15 | Kala Pharmaceuticals, Inc. | Funktionalisierte poly(ether-anhydrid)-blockcopolymere |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| FR2887886B1 (fr) † | 2005-07-01 | 2010-01-08 | Oreal | Polymere cationique neutralise, composition le comprenant et procede de traitement cosmetique |
| US20070225472A1 (en) * | 2006-03-23 | 2007-09-27 | Varshney Sunil K | Polyanhydride polymers and their uses in biomedical devices |
| EP2007358A4 (de) * | 2006-04-04 | 2012-01-25 | Stc Unm | Quellbare partikel für wirkstofffreisetzung |
| US20080014170A1 (en) * | 2006-07-14 | 2008-01-17 | Olexander Hnojewyj | Drug delivery polyanhydride composition and method |
| ITMI20061539A1 (it) * | 2006-08-02 | 2008-02-03 | Mediolanum Pharmaceuticals Ltd | Impianti sottocutanei in grado di rilasciare il principio attivo per un periodo prolungato di tempo |
| EP2049081B1 (de) | 2006-08-09 | 2012-11-14 | Intarcia Therapeutics, Inc. | Osmotische freisetzungssysteme und kolbenanordnungen |
| DE602007012559D1 (de) * | 2006-09-08 | 2011-03-31 | Univ Johns Hopkins | H die schleimhaut |
| US20090169628A1 (en) | 2006-10-17 | 2009-07-02 | Armark Authentication Technologies, Llc | Article and method for focused delivery of therapeutic and/or diagnostic materials |
| NO20065147L (no) * | 2006-11-08 | 2008-05-09 | Ntnu Tech Transfer As | Nanokompositter basert på cellulosewhiskers og celluloseplast |
| CN101679021B (zh) | 2007-03-02 | 2014-04-30 | 伊利诺伊大学评议会 | 药物颗粒送递 |
| WO2008128140A1 (en) * | 2007-04-13 | 2008-10-23 | The Regents Of The University Of Michigan | Delivery device and method for forming the same |
| HRP20130259T1 (hr) | 2007-04-23 | 2013-04-30 | Intarcia Therapeutics, Inc. | Suspenzijske formulacije inzulinotropnih peptida i njihove uporabe |
| US20080311172A1 (en) * | 2007-04-25 | 2008-12-18 | Schapira Jay N | Programmed-release, nanostructured biological construct |
| EP2242481A1 (de) * | 2007-12-31 | 2010-10-27 | Armark Authentication Technologies, LLC | Artikel und verfahren zum gezielten ausbringen von therapeutischen und/oder diagnostischen materialien |
| DK2240155T3 (da) | 2008-02-13 | 2012-09-17 | Intarcia Therapeutics Inc | Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler |
| CA2730760A1 (en) * | 2008-07-16 | 2010-01-21 | Surmodics Pharmaceuticals, Inc. | Process for preparing microparticles containing bioactive peptides |
| KR101760953B1 (ko) * | 2008-09-04 | 2017-07-24 | 아밀린 파마슈티칼스, 엘엘씨. | 비-수성 담체를 이용한 서방성 제형물 |
| US8815971B2 (en) * | 2008-12-22 | 2014-08-26 | ATRP Solutions, Inc. | Control over controlled radical polymerization processes |
| US8822610B2 (en) | 2008-12-22 | 2014-09-02 | ATRP Solutions, Inc. | Control over controlled radical polymerization processes |
| US8569421B2 (en) | 2009-04-23 | 2013-10-29 | ATRP Solutions, Inc. | Star macromolecules for personal and home care |
| US8173750B2 (en) | 2009-04-23 | 2012-05-08 | ATRP Solutions, Inc. | Star macromolecules for personal and home care |
| US9783628B2 (en) | 2009-04-23 | 2017-10-10 | ATRP Solutions, Inc. | Dual-mechanism thickening agents for hydraulic fracturing fluids |
| SMT201700583T1 (it) | 2009-09-28 | 2018-01-11 | Intarcia Therapeutics Inc | Instaurazione e/o terminazione rapida di erogazione di farmaci in modo sostanzialmente stazionario |
| WO2011084458A2 (en) * | 2009-12-15 | 2011-07-14 | The Johns Hopkins University | Polymer-based compositions and methods for treatment of peritoneal disorders |
| US9587064B2 (en) | 2010-12-08 | 2017-03-07 | ATRP Solutions, Inc. | Salt-tolerant star macromolecules |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| KR102310775B1 (ko) | 2012-05-03 | 2021-10-07 | 칼라 파마슈티컬스, 인크. | 개선된 점막 수송을 나타내는 제약 나노입자 |
| AU2013256064B2 (en) | 2012-05-03 | 2018-01-04 | Alcon Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| JP6294885B2 (ja) | 2012-08-30 | 2018-03-14 | エーティーアールピー ソリューションズ インコーポレイテッドATRP Solutions,Inc. | 星形高分子、星形高分子組成物および星形高分子の製造方法 |
| CN105263978B (zh) | 2013-02-04 | 2018-04-17 | Atrp解决方案公司 | 耐盐星形大分子 |
| JP6669499B2 (ja) | 2013-02-15 | 2020-03-18 | カラ ファーマシューティカルズ インコーポレイテッド | 治療用化合物 |
| US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
| JP2016510000A (ja) | 2013-02-20 | 2016-04-04 | カラ ファーマシューティカルズ インコーポレイテッド | 治療用化合物およびその使用 |
| US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| NZ719185A (en) | 2013-11-01 | 2017-11-24 | Kala Pharmaceuticals Inc | Crystalline forms of therapeutic compounds and uses thereof |
| US20170119683A1 (en) * | 2014-04-28 | 2017-05-04 | The Johns Hopkins University | Biopolymer-encapsulated glycosyl transferase inhibitor compositions and methods for treating diabetes and cardiac indications |
| US10023521B2 (en) | 2014-06-13 | 2018-07-17 | Rutgers, The State University Of New Jersey | Process and intermediates for preparing poly(anhydride-esters) |
| CA2956431C (en) | 2014-07-03 | 2023-01-31 | ATRP Solutions, Inc. | Surfactant-compatible star macromolecules |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| US10925639B2 (en) | 2015-06-03 | 2021-02-23 | Intarcia Therapeutics, Inc. | Implant placement and removal systems |
| CN108367079B (zh) | 2015-11-12 | 2022-11-22 | 灰色视觉公司 | 用于治疗的聚集性微粒 |
| RU2760007C2 (ru) | 2016-05-16 | 2021-11-22 | Интарсия Терапьютикс, Инк. | Полипептиды, селективные к рецепторам глюкагона, и способы их применения |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| KR20190051010A (ko) | 2016-09-08 | 2019-05-14 | 칼라 파마슈티컬스, 인크. | 치료 화합물의 결정형 및 그의 용도 |
| AU2017324713B2 (en) | 2016-09-08 | 2020-08-13 | KALA BIO, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| EP3509423A4 (de) | 2016-09-08 | 2020-05-13 | Kala Pharmaceuticals, Inc. | Kristalline formen von therapeutischen verbindungen und verwendungen davon |
| CN110225762A (zh) | 2017-01-03 | 2019-09-10 | 因塔西亚制药公司 | 包括glp-1受体激动剂的连续施用和药物的共同施用的方法 |
| CA3056923A1 (en) | 2017-03-23 | 2018-09-27 | Graybug Vision, Inc. | Drugs and compositions for the treatment of ocular disorders |
| US11160870B2 (en) | 2017-05-10 | 2021-11-02 | Graybug Vision, Inc. | Extended release microparticles and suspensions thereof for medical therapy |
| EP3969070B1 (de) * | 2019-05-13 | 2026-03-11 | University of Pittsburgh - of the Commonwealth System of Higher Education | Polymerbasiertes implantat zur netzhauttherapie und verfahren zur herstellung und verwendung davon |
| CN112495319B (zh) * | 2020-09-29 | 2023-07-04 | 海丰生物科技(北京)有限公司 | 一种环瓜氨酸肽双微球偶联物及其制备方法与应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4757128A (en) * | 1986-08-01 | 1988-07-12 | Massachusetts Institute Of Technology | High molecular weight polyanhydride and preparation thereof |
| CH671402A5 (de) * | 1985-10-02 | 1989-08-31 | Sandoz Ag | |
| US4789724A (en) * | 1986-10-17 | 1988-12-06 | Massachusetts Institute Of Technology | Preparation of anhydride copolymers |
| US5718921A (en) * | 1987-03-13 | 1998-02-17 | Massachusetts Institute Of Technology | Microspheres comprising polymer and drug dispersed there within |
| EP0712421A1 (de) * | 1993-07-23 | 1996-05-22 | Massachusetts Institute Of Technology | Nanopartikel und mikropartikel aus nichtlinearen hydrophilen-hydrophoben multiblockcopolymeren |
| US5565215A (en) * | 1993-07-23 | 1996-10-15 | Massachusettes Institute Of Technology | Biodegradable injectable particles for imaging |
| DE69505949T2 (de) * | 1994-02-17 | 1999-06-02 | Pankaj Hamilton Ontario Modi | Arzneimittel, impfstoffe und hormone in polylaktidbeschichteten mikropartikel |
| US5985309A (en) * | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
| JP2000143538A (ja) * | 1998-11-04 | 2000-05-23 | Teijin Ltd | 免疫調節剤を含有する医薬組成物 |
-
2002
- 2002-06-21 JP JP2003506884A patent/JP4758607B2/ja not_active Expired - Lifetime
- 2002-06-21 DE DE60237449T patent/DE60237449D1/de not_active Expired - Lifetime
- 2002-06-21 WO PCT/US2002/019772 patent/WO2003000237A2/en not_active Ceased
- 2002-06-21 EP EP02756268A patent/EP1406593B1/de not_active Expired - Lifetime
- 2002-06-21 AT AT02756268T patent/ATE478656T1/de not_active IP Right Cessation
- 2002-06-21 US US10/177,748 patent/US7163697B2/en not_active Expired - Lifetime
- 2002-06-21 AU AU2002322289A patent/AU2002322289A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003000237A3 (en) | 2003-03-27 |
| DE60237449D1 (de) | 2010-10-07 |
| JP2004538347A (ja) | 2004-12-24 |
| US20030086895A1 (en) | 2003-05-08 |
| WO2003000237A8 (en) | 2004-12-23 |
| AU2002322289A1 (en) | 2003-01-08 |
| JP4758607B2 (ja) | 2011-08-31 |
| EP1406593A2 (de) | 2004-04-14 |
| WO2003000237A2 (en) | 2003-01-03 |
| US7163697B2 (en) | 2007-01-16 |
| EP1406593B1 (de) | 2010-08-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE478656T1 (de) | Biologisch abbaubare polymerzusammensetzungen, zusammensetzungen und damit in beziehung stehende verwendungen | |
| WO2006063249A3 (en) | Functionalized poly (ether-anhydride) block copolymers | |
| DK1553927T3 (da) | Gel-stabiliserede, nanopartikulære aktivstof-sammensætninger | |
| BR0112054A (pt) | Composição formadora de micelas, e métodos para a administração e a proteção de um agente terapêutico | |
| BR0107874A (pt) | Implante farmacêutico para controlavelmente liberar uma droga, método para controlavelmente liberar uma droga em um indivìduo, e, método para preparar o implante | |
| EP1610751A4 (de) | Therapeutisches mittel/ligand-konjugat-zusammensetzungen, ihre syntheseverfahren und ihre anwendung | |
| TNSN06032A1 (en) | Pyridazine derivatives and their use as therapeutic agents | |
| TW200518753A (en) | Pyridylpiperazines and aminonicotinamides and their use as therapeutic agents | |
| CY1108918T1 (el) | Φαρμακευτικοι συνδυασμοι οξυκωδονης και ναλοξονης | |
| AR034356A1 (es) | Mezclas de conjugados droga insulinica-oligomero que comprenden polialquilenglicol, usos de los mismos, y metodos de obtencion | |
| MY141939A (en) | Pyridazine derivatives and their use as therapeutic agents | |
| TR200102977T2 (tr) | Yeni tedavi yöntemi. | |
| SE9802208D0 (sv) | Novel compounds | |
| BRPI0406858A (pt) | Liberação controlada de agentes altamente solúveis | |
| NO942396L (no) | Preparat med vedvarende frigiving av anti-endotelin substans | |
| DE60140997D1 (de) | Therapeutische zusammensetzungen zur pulmonalen verabreichung | |
| GEP20063869B (en) | Novel cyclohexyl sulphones | |
| AR034372A1 (es) | Composiciones farmaceuticas | |
| DE69627365D1 (de) | Verabreichungssystem mit verzoegerter freisetzung sowie langwirkende narkotische analgetika und antagonisten | |
| DK1227797T3 (da) | Farmaceutiske faststofdispersionsformuleringer | |
| SE0001916D0 (sv) | Novel formulation | |
| SE9802209D0 (sv) | Novel compounds | |
| BR0206960A (pt) | Composição farmacêutica oral, e, uso de um polìmero de ftalato de hidroxipropilmetilcelulose | |
| WO2005094265A3 (en) | Self assembling activation agents targeted using active drug release | |
| AR032036A1 (es) | Tratamiento de tumores inoperables por medio de inyeccion estereotactica de microesferas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |