CA2900050A1 - Methods for producing diketopiperazines and compositions containing diketopiperazines - Google Patents

Methods for producing diketopiperazines and compositions containing diketopiperazines Download PDF

Info

Publication number
CA2900050A1
CA2900050A1 CA2900050A CA2900050A CA2900050A1 CA 2900050 A1 CA2900050 A1 CA 2900050A1 CA 2900050 A CA2900050 A CA 2900050A CA 2900050 A CA2900050 A CA 2900050A CA 2900050 A1 CA2900050 A1 CA 2900050A1
Authority
CA
Canada
Prior art keywords
albumin
dkp
stream
composition
hsa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2900050A
Other languages
English (en)
French (fr)
Inventor
David Bar-Or
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ampio Pharmaceuticals Inc
Original Assignee
Ampio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ampio Pharmaceuticals Inc filed Critical Ampio Pharmaceuticals Inc
Publication of CA2900050A1 publication Critical patent/CA2900050A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A61K38/385—Serum albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biomedical Technology (AREA)
CA2900050A 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines Abandoned CA2900050A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361759922P 2013-02-01 2013-02-01
US61/759,922 2013-02-01
PCT/US2014/014478 WO2014121210A1 (en) 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines

Publications (1)

Publication Number Publication Date
CA2900050A1 true CA2900050A1 (en) 2014-08-07

Family

ID=51263032

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2900050A Abandoned CA2900050A1 (en) 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines

Country Status (15)

Country Link
US (1) US20150366932A1 (enExample)
EP (1) EP2950811A4 (enExample)
JP (1) JP6387019B2 (enExample)
KR (1) KR20150114984A (enExample)
CN (1) CN105188737A (enExample)
AU (1) AU2014212095B2 (enExample)
BR (1) BR112015017958A2 (enExample)
CA (1) CA2900050A1 (enExample)
EA (1) EA030414B1 (enExample)
HK (1) HK1214772A1 (enExample)
IL (1) IL240125A0 (enExample)
MX (1) MX2015009908A (enExample)
PH (1) PH12015501705A1 (enExample)
SG (2) SG11201505715RA (enExample)
WO (1) WO2014121210A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5048201B2 (ja) 2000-08-04 2012-10-17 ディーエムアイ バイオサイエンシズ インコーポレイテッド ジケトピペラジン類の使用方法とジケトピペラジン類を含む組成物
CN102210852B (zh) 2003-05-15 2016-10-19 安皮奥制药股份有限公司 T-细胞介导的疾病的治疗
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
PH12014500685B1 (en) 2011-10-10 2018-10-03 Ampio Pharmaceuticals Inc Treatment of degenerative joint disease
JP2014530063A (ja) 2011-10-10 2014-11-17 アンピオ ファーマシューティカルズ，インコーポレイテッド 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法
HK1198812A1 (en) 2011-10-28 2015-06-12 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
CA2906864A1 (en) 2013-03-15 2014-09-18 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
EP4066836A1 (en) 2014-08-18 2022-10-05 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
EP3310375A4 (en) 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES
US10426796B2 (en) * 2016-06-13 2019-10-01 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
US10456423B2 (en) 2016-06-13 2019-10-29 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
US20210016273A1 (en) * 2019-07-19 2021-01-21 University Of Utah Research Foundation Rapid sperm separation based on sperm morphology and motility
US20230074374A1 (en) * 2020-02-16 2023-03-09 PUR Biologics, Inc Methods of manufacturing extracellular matrix using aspartyl alanyl diketopiperazine (da-dkp)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE765030A (fr) * 1970-04-02 1971-08-16 Snam Progetti Composes contenant un noyau de dicetopiperazine et leur procedede fabrication
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
US5811241A (en) * 1995-09-13 1998-09-22 Cortech, Inc. Method for preparing and identifying N-substitued 1,4-piperazines and N-substituted 1,4-piperazinediones
JP2000005569A (ja) * 1998-06-24 2000-01-11 Asahi Chem Ind Co Ltd 直列多段濾過法
JP5048201B2 (ja) * 2000-08-04 2012-10-17 ディーエムアイ バイオサイエンシズ インコーポレイテッド ジケトピペラジン類の使用方法とジケトピペラジン類を含む組成物
CN1791420A (zh) * 2003-05-15 2006-06-21 Dmi生物科学公司 T－细胞介导的疾病的治疗
CN102210852B (zh) * 2003-05-15 2016-10-19 安皮奥制药股份有限公司 T-细胞介导的疾病的治疗
US7790039B2 (en) * 2003-11-24 2010-09-07 Northwest Biotherapeutics, Inc. Tangential flow filtration devices and methods for stem cell enrichment
US20050197496A1 (en) * 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
JP4970260B2 (ja) * 2004-08-20 2012-07-04 プロメティック バイオサイエンシズ，リミテッド 親和性クロマトグラフィーによるタンパク質の逐次的単離および精製スキーム
AU2010311332B2 (en) * 2009-10-30 2015-04-23 Albumedix Ltd. Albumin variants
WO2012174472A1 (en) * 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
PH12014500685B1 (en) * 2011-10-10 2018-10-03 Ampio Pharmaceuticals Inc Treatment of degenerative joint disease
JP2014530063A (ja) * 2011-10-10 2014-11-17 アンピオ ファーマシューティカルズ，インコーポレイテッド 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法
HK1198812A1 (en) * 2011-10-28 2015-06-12 Ampio Pharmaceuticals, Inc. Treatment of rhinitis

Also Published As

Publication number Publication date
EP2950811A1 (en) 2015-12-09
US20150366932A1 (en) 2015-12-24
JP6387019B2 (ja) 2018-09-05
AU2014212095A1 (en) 2015-09-10
EP2950811A4 (en) 2016-06-08
MX2015009908A (es) 2015-09-24
IL240125A0 (en) 2015-09-24
JP2016511238A (ja) 2016-04-14
SG11201505715RA (en) 2015-08-28
WO2014121210A1 (en) 2014-08-07
AU2014212095B2 (en) 2018-07-26
EA201500783A1 (ru) 2016-05-31
BR112015017958A2 (pt) 2017-07-11
KR20150114984A (ko) 2015-10-13
SG10201706213RA (en) 2017-09-28
CN105188737A (zh) 2015-12-23
HK1214772A1 (zh) 2016-08-05
PH12015501705A1 (en) 2015-10-12
EA030414B1 (ru) 2018-08-31

Similar Documents

Publication Publication Date Title
US20150366932A1 (en) Methods for producing diketopiperazines and compositions containing diketopiperazines
US10428107B2 (en) Method for isolating and purifying recombinant human serum albumin from transgenic rice grain
CN103347530B (zh) 糖尿病的治疗或预防剂
US8399620B2 (en) Purification of factor VIII using a mixed-mode or multimodal resin
EP2537862A1 (en) A process of purifying coagulation factor VIII
RS57292B1 (sr) Ace2 polipeptid
FI4108259T3 (fi) Prosessi vasta-aineiden konsentroimiseksi ja niiden terapeuttisia tuotteita
EA022821B1 (ru) Способ получения биологически активного рекомбинантного г-ксф человека
IL293286A (en) vegf mini-traps and methods of using them
CN113144169A (zh) 一种黄嘌呤氧化酶抑制肽及其应用
US20240025950A1 (en) Method of purification of recombinantly-produced rsv proteins in trimeric form
CN102321168B (zh) 新型血小板生成素拟肽复性和纯化方法
US20230287041A1 (en) Improvements to wash solutions for anion exchange chromatography in a method of purification of recombinantly-produced rsv proteins
CN120796422B (zh) 一种桑叶降血压活性肽及其制备方法与应用
CN104163850A (zh) 一种小分子抗体亲和肽及其应用
CN1313487C (zh) 具有抗菌作用的免疫活性肽（Trpi）
CN1563404A (zh) 米糠蛋白降血压肽(ace 抑制肽)的制备方法
CN105061558A (zh) 一种金枪鱼蒸煮液活性肽及其制备方法和糖尿病治疗用途
CN118894920A (zh) 一种具有降血糖作用的功能肽及制备方法和应用
CN113072621B (zh) 一种牦牛骨降血压肽及其制备方法与应用
CN116120431A (zh) 一种抗氧化胶原多肽、制备方法及其应用
CN115161371A (zh) 一种牛乳酪蛋白水解制备寡肽的方法
KR20200038309A (ko) 폰 빌레브란트 인자의 바이러스 여과 방법
Merah PURIFICATION OF POTENT ANGIOTENSIN CONVERTING ENZYME (ACE)-INHIBITORY PEPTIDES DERIVED FROM RED TILAPIA (Oreochromis Sp.) BY-PRODUCTS
JPH0482898A (ja) 新規なペプチド及びアンジオテンシン変換酵素阻害剤

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20200204