CA2900050A1 - Methods for producing diketopiperazines and compositions containing diketopiperazines - Google Patents

Methods for producing diketopiperazines and compositions containing diketopiperazines Download PDF

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Publication number
CA2900050A1
CA2900050A1 CA2900050A CA2900050A CA2900050A1 CA 2900050 A1 CA2900050 A1 CA 2900050A1 CA 2900050 A CA2900050 A CA 2900050A CA 2900050 A CA2900050 A CA 2900050A CA 2900050 A1 CA2900050 A1 CA 2900050A1
Authority
CA
Canada
Prior art keywords
albumin
dkp
stream
composition
hsa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2900050A
Other languages
English (en)
French (fr)
Inventor
David Bar-Or
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ampio Pharmaceuticals Inc
Original Assignee
Ampio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ampio Pharmaceuticals Inc filed Critical Ampio Pharmaceuticals Inc
Publication of CA2900050A1 publication Critical patent/CA2900050A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • A61K38/385Serum albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/06Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Preparation (AREA)
  • Biomedical Technology (AREA)
  • Electrochemistry (AREA)
CA2900050A 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines Abandoned CA2900050A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361759922P 2013-02-01 2013-02-01
US61/759,922 2013-02-01
PCT/US2014/014478 WO2014121210A1 (en) 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines

Publications (1)

Publication Number Publication Date
CA2900050A1 true CA2900050A1 (en) 2014-08-07

Family

ID=51263032

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2900050A Abandoned CA2900050A1 (en) 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines

Country Status (15)

Country Link
US (1) US20150366932A1 (enExample)
EP (1) EP2950811A4 (enExample)
JP (1) JP6387019B2 (enExample)
KR (1) KR20150114984A (enExample)
CN (1) CN105188737A (enExample)
AU (1) AU2014212095B2 (enExample)
BR (1) BR112015017958A2 (enExample)
CA (1) CA2900050A1 (enExample)
EA (1) EA030414B1 (enExample)
HK (1) HK1214772A1 (enExample)
IL (1) IL240125A0 (enExample)
MX (1) MX2015009908A (enExample)
PH (1) PH12015501705A1 (enExample)
SG (2) SG11201505715RA (enExample)
WO (1) WO2014121210A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1311269T3 (da) 2000-08-04 2012-03-26 Dmi Biosciences Inc Fremgangsmåde til anvendelse af diketopiperaziner og sammensætning, som indeholder dem
ES2572975T3 (es) 2003-05-15 2016-06-03 Ampio Pharmaceuticals, Inc. Tratamiento de enfermedades mediadas por los linfocitos T
WO2009146320A1 (en) 2008-05-27 2009-12-03 Dmi Life Sciences, Inc. Therapeutic methods and compounds
BR112014007675A2 (pt) 2011-10-10 2017-04-18 Ampio Pharmaceuticals Inc tratamento de doença articular degenerativa
BR112014007657A2 (pt) 2011-10-10 2017-04-11 Ampio Pharmaceuticals Inc dispositivos médicos implantáveis com tolerância imune aperfeiçoada e métodos para produção e implantação
WO2013063413A1 (en) 2011-10-28 2013-05-02 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
US9808454B2 (en) 2013-03-15 2017-11-07 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
EP3183240A4 (en) 2014-08-18 2018-06-27 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
HK1246669A1 (zh) 2015-06-22 2018-09-14 Ampio Pharmaceuticals, Inc. 人血清白蛋白低分子量组分在疾病治疗中的应用
US10456423B2 (en) 2016-06-13 2019-10-29 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
US10426796B2 (en) * 2016-06-13 2019-10-01 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
US20210016273A1 (en) * 2019-07-19 2021-01-21 University Of Utah Research Foundation Rapid sperm separation based on sperm morphology and motility
WO2021163693A1 (en) * 2020-02-16 2021-08-19 Pur Biologics, Inc. Methods of manufacturing extracellular matrix using aspartyl alanyl diketopiperazine (da-dkp)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE765030A (fr) * 1970-04-02 1971-08-16 Snam Progetti Composes contenant un noyau de dicetopiperazine et leur procedede fabrication
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
US5811241A (en) * 1995-09-13 1998-09-22 Cortech, Inc. Method for preparing and identifying N-substitued 1,4-piperazines and N-substituted 1,4-piperazinediones
JP2000005569A (ja) * 1998-06-24 2000-01-11 Asahi Chem Ind Co Ltd 直列多段濾過法
DK1311269T3 (da) * 2000-08-04 2012-03-26 Dmi Biosciences Inc Fremgangsmåde til anvendelse af diketopiperaziner og sammensætning, som indeholder dem
CN101279094A (zh) * 2003-05-15 2008-10-08 Dmi生物科学公司 T-细胞介导的疾病的治疗
ES2572975T3 (es) * 2003-05-15 2016-06-03 Ampio Pharmaceuticals, Inc. Tratamiento de enfermedades mediadas por los linfocitos T
US7790039B2 (en) * 2003-11-24 2010-09-07 Northwest Biotherapeutics, Inc. Tangential flow filtration devices and methods for stem cell enrichment
US20050197496A1 (en) * 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
PL1786273T3 (pl) * 2004-08-20 2019-05-31 Prometic Biosciences Ltd Schematy sekwencyjnego izolowania i oczyszczania białek sposobem chromatografii powinowactwa
MX2012004793A (es) * 2009-10-30 2012-07-20 Novozymes Biopharma Dk As Variantes de albumina.
WO2012174472A1 (en) * 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014007657A2 (pt) * 2011-10-10 2017-04-11 Ampio Pharmaceuticals Inc dispositivos médicos implantáveis com tolerância imune aperfeiçoada e métodos para produção e implantação
BR112014007675A2 (pt) * 2011-10-10 2017-04-18 Ampio Pharmaceuticals Inc tratamento de doença articular degenerativa
WO2013063413A1 (en) * 2011-10-28 2013-05-02 Ampio Pharmaceuticals, Inc. Treatment of rhinitis

Also Published As

Publication number Publication date
BR112015017958A2 (pt) 2017-07-11
HK1214772A1 (zh) 2016-08-05
KR20150114984A (ko) 2015-10-13
EA030414B1 (ru) 2018-08-31
EA201500783A1 (ru) 2016-05-31
CN105188737A (zh) 2015-12-23
PH12015501705A1 (en) 2015-10-12
US20150366932A1 (en) 2015-12-24
WO2014121210A1 (en) 2014-08-07
IL240125A0 (en) 2015-09-24
SG10201706213RA (en) 2017-09-28
EP2950811A4 (en) 2016-06-08
EP2950811A1 (en) 2015-12-09
SG11201505715RA (en) 2015-08-28
AU2014212095B2 (en) 2018-07-26
MX2015009908A (es) 2015-09-24
JP6387019B2 (ja) 2018-09-05
AU2014212095A1 (en) 2015-09-10
JP2016511238A (ja) 2016-04-14

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20200204

FZDE Discontinued

Effective date: 20200204