AU2014212095B2 - Methods for producing diketopiperazines and compositions containing diketopiperazines - Google Patents

Methods for producing diketopiperazines and compositions containing diketopiperazines Download PDF

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Publication number
AU2014212095B2
AU2014212095B2 AU2014212095A AU2014212095A AU2014212095B2 AU 2014212095 B2 AU2014212095 B2 AU 2014212095B2 AU 2014212095 A AU2014212095 A AU 2014212095A AU 2014212095 A AU2014212095 A AU 2014212095A AU 2014212095 B2 AU2014212095 B2 AU 2014212095B2
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AU
Australia
Prior art keywords
albumin
dkp
stream
pct
rich
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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AU2014212095A
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English (en)
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AU2014212095A1 (en
Inventor
David Bar-Or
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ampio Pharmaceuticals Inc
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Ampio Pharmaceuticals Inc
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Publication of AU2014212095A1 publication Critical patent/AU2014212095A1/en
Application granted granted Critical
Publication of AU2014212095B2 publication Critical patent/AU2014212095B2/en
Ceased legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A61K38/385—Serum albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biomedical Technology (AREA)
AU2014212095A 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines Ceased AU2014212095B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361759922P 2013-02-01 2013-02-01
US61/759,922 2013-02-01
PCT/US2014/014478 WO2014121210A1 (en) 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines

Publications (2)

Publication Number Publication Date
AU2014212095A1 AU2014212095A1 (en) 2015-09-10
AU2014212095B2 true AU2014212095B2 (en) 2018-07-26

Family

ID=51263032

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014212095A Ceased AU2014212095B2 (en) 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines

Country Status (15)

Country Link
US (1) US20150366932A1 (enExample)
EP (1) EP2950811A4 (enExample)
JP (1) JP6387019B2 (enExample)
KR (1) KR20150114984A (enExample)
CN (1) CN105188737A (enExample)
AU (1) AU2014212095B2 (enExample)
BR (1) BR112015017958A2 (enExample)
CA (1) CA2900050A1 (enExample)
EA (1) EA030414B1 (enExample)
HK (1) HK1214772A1 (enExample)
IL (1) IL240125A0 (enExample)
MX (1) MX2015009908A (enExample)
PH (1) PH12015501705A1 (enExample)
SG (2) SG11201505715RA (enExample)
WO (1) WO2014121210A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001279313B2 (en) 2000-08-04 2007-03-01 Ampio Pharmaceuticals, Inc. Method of using diketopiperazines and composition containing them
CA3050734A1 (en) 2003-05-15 2004-12-02 Ampio Pharmaceuticals, Inc. Treatment of t-cell mediated diseases
WO2009146320A1 (en) 2008-05-27 2009-12-03 Dmi Life Sciences, Inc. Therapeutic methods and compounds
EP2766029B1 (en) 2011-10-10 2020-03-25 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease
EA027343B1 (ru) 2011-10-10 2017-07-31 Ампио Фармасьютикалз, Инк. Имплантируемые устройства медицинского назначения с повышенной иммунной толерантностью и способы изготовления и имплантирования
CA2846394A1 (en) 2011-10-28 2013-05-02 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
BR112015020469A2 (pt) 2013-03-15 2020-01-28 Ampio Pharmaceuticals Inc Usos de da-dkp, composição e método para fornecimento de células-tronco a umindivíduo
AU2015305611B2 (en) 2014-08-18 2020-04-23 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
US11389512B2 (en) 2015-06-22 2022-07-19 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
US10426796B2 (en) * 2016-06-13 2019-10-01 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
US10456423B2 (en) 2016-06-13 2019-10-29 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
US20210016273A1 (en) * 2019-07-19 2021-01-21 University Of Utah Research Foundation Rapid sperm separation based on sperm morphology and motility
US20230074374A1 (en) * 2020-02-16 2023-03-09 PUR Biologics, Inc Methods of manufacturing extracellular matrix using aspartyl alanyl diketopiperazine (da-dkp)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092556A5 (enExample) * 1970-04-02 1972-01-21 Snam Progetti
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
US5811241A (en) * 1995-09-13 1998-09-22 Cortech, Inc. Method for preparing and identifying N-substitued 1,4-piperazines and N-substituted 1,4-piperazinediones
JP2000005569A (ja) * 1998-06-24 2000-01-11 Asahi Chem Ind Co Ltd 直列多段濾過法
AU2001279313B2 (en) * 2000-08-04 2007-03-01 Ampio Pharmaceuticals, Inc. Method of using diketopiperazines and composition containing them
CA3050734A1 (en) * 2003-05-15 2004-12-02 Ampio Pharmaceuticals, Inc. Treatment of t-cell mediated diseases
CN101279094A (zh) * 2003-05-15 2008-10-08 Dmi生物科学公司 T-细胞介导的疾病的治疗
US7790039B2 (en) * 2003-11-24 2010-09-07 Northwest Biotherapeutics, Inc. Tangential flow filtration devices and methods for stem cell enrichment
US20050197496A1 (en) * 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
AU2005277190B2 (en) * 2004-08-20 2011-03-03 American National Red Cross Sequential protein isolation and purification schemes by affinity chromatography
CN102741280B (zh) * 2009-10-30 2015-12-02 诺维信生物制药丹麦公司 白蛋白变体
WO2012174472A1 (en) * 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
EA027343B1 (ru) * 2011-10-10 2017-07-31 Ампио Фармасьютикалз, Инк. Имплантируемые устройства медицинского назначения с повышенной иммунной толерантностью и способы изготовления и имплантирования
EP2766029B1 (en) * 2011-10-10 2020-03-25 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease
CA2846394A1 (en) * 2011-10-28 2013-05-02 Ampio Pharmaceuticals, Inc. Treatment of rhinitis

Also Published As

Publication number Publication date
EA201500783A1 (ru) 2016-05-31
US20150366932A1 (en) 2015-12-24
CN105188737A (zh) 2015-12-23
PH12015501705A1 (en) 2015-10-12
EP2950811A1 (en) 2015-12-09
MX2015009908A (es) 2015-09-24
IL240125A0 (en) 2015-09-24
EA030414B1 (ru) 2018-08-31
BR112015017958A2 (pt) 2017-07-11
KR20150114984A (ko) 2015-10-13
EP2950811A4 (en) 2016-06-08
SG11201505715RA (en) 2015-08-28
HK1214772A1 (zh) 2016-08-05
CA2900050A1 (en) 2014-08-07
JP2016511238A (ja) 2016-04-14
JP6387019B2 (ja) 2018-09-05
AU2014212095A1 (en) 2015-09-10
WO2014121210A1 (en) 2014-08-07
SG10201706213RA (en) 2017-09-28

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired