PH12015501705A1 - Methods for producing diketopiperazines and compositions containing diketopiperazines - Google Patents
Methods for producing diketopiperazines and compositions containing diketopiperazinesInfo
- Publication number
- PH12015501705A1 PH12015501705A1 PH12015501705A PH12015501705A PH12015501705A1 PH 12015501705 A1 PH12015501705 A1 PH 12015501705A1 PH 12015501705 A PH12015501705 A PH 12015501705A PH 12015501705 A PH12015501705 A PH 12015501705A PH 12015501705 A1 PH12015501705 A1 PH 12015501705A1
- Authority
- PH
- Philippines
- Prior art keywords
- dkp
- albumin
- diketopiperazines
- methods
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 102000009027 Albumins Human genes 0.000 abstract 6
- 108010088751 Albumins Proteins 0.000 abstract 6
- 230000001225 therapeutic effect Effects 0.000 abstract 3
- 102000016622 Dipeptidyl Peptidase 4 Human genes 0.000 abstract 2
- 101000930822 Giardia intestinalis Dipeptidyl-peptidase 4 Proteins 0.000 abstract 2
- RVLCUCVJZVRNDC-IMJSIDKUSA-N 2-[(2s,5s)-5-methyl-3,6-dioxopiperazin-2-yl]acetic acid Chemical compound C[C@@H]1NC(=O)[C@H](CC(O)=O)NC1=O RVLCUCVJZVRNDC-IMJSIDKUSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 abstract 1
- 108010038239 aspartyl-alanyl-diketopiperazine Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A61K38/385—Serum albumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Biomedical Technology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361759922P | 2013-02-01 | 2013-02-01 | |
| PCT/US2014/014478 WO2014121210A1 (en) | 2013-02-01 | 2014-02-03 | Methods for producing diketopiperazines and compositions containing diketopiperazines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12015501705A1 true PH12015501705A1 (en) | 2015-10-12 |
Family
ID=51263032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12015501705A PH12015501705A1 (en) | 2013-02-01 | 2015-07-31 | Methods for producing diketopiperazines and compositions containing diketopiperazines |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20150366932A1 (enExample) |
| EP (1) | EP2950811A4 (enExample) |
| JP (1) | JP6387019B2 (enExample) |
| KR (1) | KR20150114984A (enExample) |
| CN (1) | CN105188737A (enExample) |
| AU (1) | AU2014212095B2 (enExample) |
| BR (1) | BR112015017958A2 (enExample) |
| CA (1) | CA2900050A1 (enExample) |
| EA (1) | EA030414B1 (enExample) |
| HK (1) | HK1214772A1 (enExample) |
| IL (1) | IL240125A0 (enExample) |
| MX (1) | MX2015009908A (enExample) |
| PH (1) | PH12015501705A1 (enExample) |
| SG (2) | SG11201505715RA (enExample) |
| WO (1) | WO2014121210A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5048201B2 (ja) | 2000-08-04 | 2012-10-17 | ディーエムアイ バイオサイエンシズ インコーポレイテッド | ジケトピペラジン類の使用方法とジケトピペラジン類を含む組成物 |
| CN102210852B (zh) | 2003-05-15 | 2016-10-19 | 安皮奥制药股份有限公司 | T-细胞介导的疾病的治疗 |
| JP5856843B2 (ja) | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ，インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| PH12014500685B1 (en) | 2011-10-10 | 2018-10-03 | Ampio Pharmaceuticals Inc | Treatment of degenerative joint disease |
| JP2014530063A (ja) | 2011-10-10 | 2014-11-17 | アンピオ ファーマシューティカルズ，インコーポレイテッド | 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法 |
| HK1198812A1 (en) | 2011-10-28 | 2015-06-12 | Ampio Pharmaceuticals, Inc. | Treatment of rhinitis |
| CA2906864A1 (en) | 2013-03-15 | 2014-09-18 | Ampio Pharmaceuticals, Inc. | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
| EP4066836A1 (en) | 2014-08-18 | 2022-10-05 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
| EP3310375A4 (en) | 2015-06-22 | 2019-02-20 | Ampio Pharmaceuticals, Inc. | USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES |
| US10426796B2 (en) * | 2016-06-13 | 2019-10-01 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| US10456423B2 (en) | 2016-06-13 | 2019-10-29 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| US20210016273A1 (en) * | 2019-07-19 | 2021-01-21 | University Of Utah Research Foundation | Rapid sperm separation based on sperm morphology and motility |
| US20230074374A1 (en) * | 2020-02-16 | 2023-03-09 | PUR Biologics, Inc | Methods of manufacturing extracellular matrix using aspartyl alanyl diketopiperazine (da-dkp) |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE765030A (fr) * | 1970-04-02 | 1971-08-16 | Snam Progetti | Composes contenant un noyau de dicetopiperazine et leur procedede fabrication |
| US5561115A (en) * | 1994-08-10 | 1996-10-01 | Bayer Corporation | Low temperature albumin fractionation using sodium caprylate as a partitioning agent |
| US5811241A (en) * | 1995-09-13 | 1998-09-22 | Cortech, Inc. | Method for preparing and identifying N-substitued 1,4-piperazines and N-substituted 1,4-piperazinediones |
| JP2000005569A (ja) * | 1998-06-24 | 2000-01-11 | Asahi Chem Ind Co Ltd | 直列多段濾過法 |
| JP5048201B2 (ja) * | 2000-08-04 | 2012-10-17 | ディーエムアイ バイオサイエンシズ インコーポレイテッド | ジケトピペラジン類の使用方法とジケトピペラジン類を含む組成物 |
| CN1791420A (zh) * | 2003-05-15 | 2006-06-21 | Dmi生物科学公司 | T－细胞介导的疾病的治疗 |
| CN102210852B (zh) * | 2003-05-15 | 2016-10-19 | 安皮奥制药股份有限公司 | T-细胞介导的疾病的治疗 |
| US7790039B2 (en) * | 2003-11-24 | 2010-09-07 | Northwest Biotherapeutics, Inc. | Tangential flow filtration devices and methods for stem cell enrichment |
| US20050197496A1 (en) * | 2004-03-04 | 2005-09-08 | Gtc Biotherapeutics, Inc. | Methods of protein fractionation using high performance tangential flow filtration |
| JP4970260B2 (ja) * | 2004-08-20 | 2012-07-04 | プロメティック バイオサイエンシズ，リミテッド | 親和性クロマトグラフィーによるタンパク質の逐次的単離および精製スキーム |
| AU2010311332B2 (en) * | 2009-10-30 | 2015-04-23 | Albumedix Ltd. | Albumin variants |
| WO2012174472A1 (en) * | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| PH12014500685B1 (en) * | 2011-10-10 | 2018-10-03 | Ampio Pharmaceuticals Inc | Treatment of degenerative joint disease |
| JP2014530063A (ja) * | 2011-10-10 | 2014-11-17 | アンピオ ファーマシューティカルズ，インコーポレイテッド | 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法 |
| HK1198812A1 (en) * | 2011-10-28 | 2015-06-12 | Ampio Pharmaceuticals, Inc. | Treatment of rhinitis |
-
2014
- 2014-02-03 WO PCT/US2014/014478 patent/WO2014121210A1/en not_active Ceased
- 2014-02-03 CA CA2900050A patent/CA2900050A1/en not_active Abandoned
- 2014-02-03 MX MX2015009908A patent/MX2015009908A/es unknown
- 2014-02-03 US US14/765,018 patent/US20150366932A1/en not_active Abandoned
- 2014-02-03 SG SG11201505715RA patent/SG11201505715RA/en unknown
- 2014-02-03 EP EP14745933.3A patent/EP2950811A4/en not_active Withdrawn
- 2014-02-03 KR KR1020157023636A patent/KR20150114984A/ko not_active Withdrawn
- 2014-02-03 BR BR112015017958A patent/BR112015017958A2/pt not_active IP Right Cessation
- 2014-02-03 AU AU2014212095A patent/AU2014212095B2/en not_active Ceased
- 2014-02-03 HK HK16102846.4A patent/HK1214772A1/zh unknown
- 2014-02-03 EA EA201500783A patent/EA030414B1/ru not_active IP Right Cessation
- 2014-02-03 CN CN201480015923.2A patent/CN105188737A/zh active Pending
- 2014-02-03 SG SG10201706213RA patent/SG10201706213RA/en unknown
- 2014-02-03 JP JP2015556207A patent/JP6387019B2/ja not_active Expired - Fee Related
-
2015
- 2015-07-23 IL IL240125A patent/IL240125A0/en unknown
- 2015-07-31 PH PH12015501705A patent/PH12015501705A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2950811A1 (en) | 2015-12-09 |
| US20150366932A1 (en) | 2015-12-24 |
| JP6387019B2 (ja) | 2018-09-05 |
| AU2014212095A1 (en) | 2015-09-10 |
| EP2950811A4 (en) | 2016-06-08 |
| MX2015009908A (es) | 2015-09-24 |
| IL240125A0 (en) | 2015-09-24 |
| CA2900050A1 (en) | 2014-08-07 |
| JP2016511238A (ja) | 2016-04-14 |
| SG11201505715RA (en) | 2015-08-28 |
| WO2014121210A1 (en) | 2014-08-07 |
| AU2014212095B2 (en) | 2018-07-26 |
| EA201500783A1 (ru) | 2016-05-31 |
| BR112015017958A2 (pt) | 2017-07-11 |
| KR20150114984A (ko) | 2015-10-13 |
| SG10201706213RA (en) | 2017-09-28 |
| CN105188737A (zh) | 2015-12-23 |
| HK1214772A1 (zh) | 2016-08-05 |
| EA030414B1 (ru) | 2018-08-31 |
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