CA2841831C - Methods and compositions for production of vaccinia virus - Google Patents
Methods and compositions for production of vaccinia virus Download PDFInfo
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- CA2841831C CA2841831C CA2841831A CA2841831A CA2841831C CA 2841831 C CA2841831 C CA 2841831C CA 2841831 A CA2841831 A CA 2841831A CA 2841831 A CA2841831 A CA 2841831A CA 2841831 C CA2841831 C CA 2841831C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12N2710/00011—Details
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- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24151—Methods of production or purification of viral material
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| WO2020011754A1 (en) | 2018-07-09 | 2020-01-16 | Transgene | Chimeric vaccinia viruses |
| EP3617230A1 (en) | 2018-09-03 | 2020-03-04 | BioInvent International AB | Novel antibodies and nucleotide sequences, and uses thereof |
| AU2019384164A1 (en) * | 2018-11-21 | 2021-06-03 | Kalivir Immunotherapeutics, Inc. | Manufacture of virus |
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| KR102228267B1 (ko) | 2019-01-25 | 2021-03-17 | 바이로큐어 주식회사 | Bhk-21 세포를 이용한 바이러스 생산방법 |
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| CA3183701A1 (en) | 2020-06-22 | 2021-12-30 | Sung Jin Kim | Method for large scale-production of vaccinia virus using suspension cells |
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| KR20230110545A (ko) | 2020-11-19 | 2023-07-24 | 칼리버 임뮤노쎄라퓨틱스, 인크. | 종양 미세환경 재형성에 의한 종양용해 면역요법 |
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| CN114395538A (zh) * | 2022-01-19 | 2022-04-26 | 和元生物技术（上海）股份有限公司 | 一种促进重组病毒载体向细胞外分泌的方法 |
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| US20140162342A1 (en) | 2014-06-12 |
| EP2739293B1 (en) | 2020-06-10 |
| JP6243333B2 (ja) | 2017-12-06 |
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| CN103732236B (zh) | 2017-09-15 |
| US10202581B2 (en) | 2019-02-12 |
| BR112014000787B1 (pt) | 2021-04-13 |
| US10767166B2 (en) | 2020-09-08 |
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| ES2813413T3 (es) | 2021-03-23 |
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| AU2012294606A1 (en) | 2014-01-23 |
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