CA2820419A1 - Agents and methods for inhibiting human pluripotent stem cell growth - Google Patents
Agents and methods for inhibiting human pluripotent stem cell growth Download PDFInfo
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- CA2820419A1 CA2820419A1 CA2820419A CA2820419A CA2820419A1 CA 2820419 A1 CA2820419 A1 CA 2820419A1 CA 2820419 A CA2820419 A CA 2820419A CA 2820419 A CA2820419 A CA 2820419A CA 2820419 A1 CA2820419 A1 CA 2820419A1
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5073—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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| PCT/US2010/059586 WO2012078153A1 (en) | 2010-12-08 | 2010-12-08 | Agents and methods for inhibiting human pluripotent stem cell growth |
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| ES2674567T3 (es) | 2010-05-21 | 2018-07-02 | Merrimack Pharmaceuticals, Inc. | Proteínas de fusión biespecíficas |
| JP6312591B2 (ja) | 2011-06-21 | 2018-04-18 | ノヴォ ノルディスク アー／エス | 多能性幹細胞からの胚体内胚葉の効率的な誘導 |
| US10072242B2 (en) | 2013-03-25 | 2018-09-11 | Foundation For Biomedical Research And Innovation At Kobe | Cell sorting method |
| CN105283541B (zh) * | 2013-05-30 | 2019-02-19 | 味之素株式会社 | 干细胞培养用培养基 |
| WO2015025967A1 (ja) | 2013-08-23 | 2015-02-26 | 住友化学株式会社 | 網膜組織及び網膜関連細胞の製造方法 |
| EP3097186B1 (en) | 2014-01-21 | 2019-05-08 | The Medical College of Wisconsin, Inc. | Methods for selective inhibition of pluripotent stem cells |
| CA2944393C (en) | 2014-03-31 | 2019-02-05 | Ajinomoto Co., Inc. | Medium for stem cell use |
| US11028369B2 (en) | 2015-08-13 | 2021-06-08 | Beihao Stem Cell And Regenerative Medicine Research Institute Co., Ltd. | Induced extended pluripotent stem cells, method of making and using |
| CA3000742A1 (en) | 2015-10-02 | 2017-04-06 | Silver Creek Pharmaceuticals, Inc. | Bi-specific therapeutic proteins for tissue repair |
| WO2017123806A1 (en) | 2016-01-12 | 2017-07-20 | Cedars-Sinai Medical Center | A method of non destructive monitoring of biological processes in microfluidic tissue culture systems |
| WO2018140647A1 (en) * | 2017-01-25 | 2018-08-02 | Cedars-Sinai Medical Center | In vitro induction of mammary-like differentiation from human pluripotent stem cells |
| US11746331B2 (en) | 2017-01-27 | 2023-09-05 | Kaneka Corporation | Endodermal cell population, and method for producing cell population of any of three germ layers from pluripotent cell |
| EP3592838A4 (en) * | 2017-03-07 | 2021-01-13 | Platelet Biogenesis, Inc. | RECIRCULATING BIOREACTOR |
| US11767513B2 (en) | 2017-03-14 | 2023-09-26 | Cedars-Sinai Medical Center | Neuromuscular junction |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| CN110506109B (zh) | 2017-06-05 | 2024-03-12 | 泰尔茂株式会社 | 细胞培养物的制造方法 |
| US10391156B2 (en) | 2017-07-12 | 2019-08-27 | Viacyte, Inc. | University donor cells and related methods |
| CN108570443A (zh) * | 2017-12-05 | 2018-09-25 | 皓昇莱生物制药有限公司 | 一种用于培养尿液来源细胞的培养基 |
| US12161676B2 (en) | 2018-03-23 | 2024-12-10 | Cedars-Sinai Medical Center | Methods of use of islet cells |
| JP7016185B2 (ja) * | 2018-03-28 | 2022-02-04 | 国立大学法人大阪大学 | 幹細胞由来涙腺組織の作製方法 |
| JP7464532B2 (ja) | 2018-04-06 | 2024-04-09 | シーダーズ－サイナイ メディカル センター | マイクロ流体チップ上のヒト多能性幹細胞由来の神経変性疾患モデル |
| WO2019195800A1 (en) | 2018-04-06 | 2019-10-10 | Cedars-Sinai Medical Center | Novel differentiation technique to generate dopaminergic neurons from induced pluripotent stem cells |
| US20210033628A1 (en) | 2018-04-30 | 2021-02-04 | Cedars-Sinai Medical Center | Diagnostic and drug screening for molecular signatures of early onset sporadic parkinson's disease |
| CN110684714B (zh) * | 2018-07-05 | 2023-05-09 | 广东博溪生物科技有限公司 | 一种屏障功能弱化模型的构建方法 |
| BR112021000996A2 (pt) | 2018-07-19 | 2021-04-20 | Platelet Biogenesis, Inc. | biorreator de recirculação empilhado |
| US10724052B2 (en) | 2018-09-07 | 2020-07-28 | Crispr Therapeutics Ag | Universal donor cells |
| TWI862513B (zh) * | 2018-09-19 | 2024-11-21 | 日商千紙鶴治療公司 | 包含胰島素產生細胞之細胞集團、包含該細胞集團之醫藥、其用途及製造方法 |
| EP3739040B1 (en) | 2018-09-27 | 2023-07-05 | Osaka University | Sheeting method for pluripotent stem cell-derived cells |
| EP3901252A4 (en) * | 2018-12-21 | 2022-10-26 | National University Corporation Hokkaido University | COMPOSITION FOR REMOVAL OF PLURIPOTENTER STEM CELLS AND METHOD OF REMOVAL OF PLURIPOTENTER STEM CELLS |
| CN110373375A (zh) * | 2019-03-19 | 2019-10-25 | 杭州原生生物科技有限公司 | 一种制备纤维细胞作为细胞培养基的方法和用途 |
| AU2020340622A1 (en) | 2019-09-05 | 2022-03-03 | Crispr Therapeutics Ag | Universal donor cells |
| US11118195B2 (en) | 2019-09-05 | 2021-09-14 | Crispr Therapeutics Ag | Universal donor cells |
| KR20230051519A (ko) | 2020-08-15 | 2023-04-18 | 리제너론 파마슈티칼스 인코포레이티드 | 칼시토닌 수용체 (calcr)를 인코딩하는 변이체 핵산 분자를 갖는 대상체에서 비만의 치료 |
| KR20230146007A (ko) | 2020-12-31 | 2023-10-18 | 크리스퍼 테라퓨틱스 아게 | 범용 공여자 세포 |
| TW202523836A (zh) * | 2023-12-12 | 2025-06-16 | 佛教慈濟醫療財團法人 | 選擇性去除未分化多潛能幹細胞的方法 |
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| US5861483A (en) * | 1996-04-03 | 1999-01-19 | Pro-Neuron, Inc. | Inhibitor of stem cell proliferation and uses thereof |
| WO2000027995A1 (en) | 1998-11-09 | 2000-05-18 | Monash University | Embryonic stem cells |
| US8597947B2 (en) * | 2004-12-29 | 2013-12-03 | Hadasit Medical Research Services & Development Limited | Undifferentiated stem cell culture systems |
| US20080070303A1 (en) * | 2005-11-21 | 2008-03-20 | West Michael D | Methods to accelerate the isolation of novel cell strains from pluripotent stem cells and cells obtained thereby |
| US20120295346A1 (en) * | 2009-07-22 | 2012-11-22 | Tufts University | Methods and compositions for modulating membrane potential to influence cell behavior |
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- 2010-12-08 AU AU2010365057A patent/AU2010365057B2/en not_active Ceased
- 2010-12-08 CN CN201080071181.7A patent/CN103354835B/zh not_active Expired - Fee Related
- 2010-12-08 ES ES10860584.1T patent/ES2690663T3/es active Active
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2016
- 2016-06-10 US US15/178,852 patent/US20160281058A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN103354835A (zh) | 2013-10-16 |
| US9365830B2 (en) | 2016-06-14 |
| EP2649177B1 (en) | 2018-09-05 |
| EP2649177A1 (en) | 2013-10-16 |
| US20160281058A1 (en) | 2016-09-29 |
| AU2010365057B2 (en) | 2016-12-22 |
| US20130280802A1 (en) | 2013-10-24 |
| EP2649177A4 (en) | 2014-04-23 |
| WO2012078153A1 (en) | 2012-06-14 |
| ES2690663T3 (es) | 2018-11-21 |
| JP2014501518A (ja) | 2014-01-23 |
| JP5875597B2 (ja) | 2016-03-02 |
| CN103354835B (zh) | 2016-03-02 |
| AU2010365057A1 (en) | 2013-06-20 |
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