CA2772328C - Novel forms of a multicyclic compound - Google Patents
Novel forms of a multicyclic compound Download PDFInfo
- Publication number
- CA2772328C CA2772328C CA2772328A CA2772328A CA2772328C CA 2772328 C CA2772328 C CA 2772328C CA 2772328 A CA2772328 A CA 2772328A CA 2772328 A CA2772328 A CA 2772328A CA 2772328 C CA2772328 C CA 2772328C
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- CA
- Canada
- Prior art keywords
- compound
- xrpd
- crystalline
- crystalline form
- ray powder
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23718009P | 2009-08-26 | 2009-08-26 | |
| US61/237,180 | 2009-08-26 | ||
| PCT/US2010/046671 WO2011028580A1 (en) | 2009-08-26 | 2010-08-25 | Novel forms of a multicyclic compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2772328A1 CA2772328A1 (en) | 2011-03-10 |
| CA2772328C true CA2772328C (en) | 2017-06-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2772328A Expired - Fee Related CA2772328C (en) | 2009-08-26 | 2010-08-25 | Novel forms of a multicyclic compound |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8633314B2 (enExample) |
| EP (1) | EP2470540B1 (enExample) |
| JP (3) | JP2013503173A (enExample) |
| KR (1) | KR20120092100A (enExample) |
| CN (1) | CN102482282A (enExample) |
| AU (1) | AU2010289746B2 (enExample) |
| BR (1) | BR112012004053A2 (enExample) |
| CA (1) | CA2772328C (enExample) |
| CL (1) | CL2012000478A1 (enExample) |
| DK (1) | DK2470540T3 (enExample) |
| EA (1) | EA020756B1 (enExample) |
| ES (1) | ES2572652T3 (enExample) |
| IL (1) | IL218132B (enExample) |
| MX (1) | MX2012002456A (enExample) |
| MY (1) | MY156873A (enExample) |
| NZ (1) | NZ598883A (enExample) |
| SG (1) | SG178852A1 (enExample) |
| UA (1) | UA110604C2 (enExample) |
| WO (1) | WO2011028580A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013503173A (ja) * | 2009-08-26 | 2013-01-31 | セファロン、インク． | 多環系化合物の新規形態 |
| CA2967828A1 (en) | 2014-11-26 | 2016-06-02 | Cephalon, Inc. | Crystalline forms of parp inhibitors |
| HRP20240136T1 (hr) | 2016-06-29 | 2024-04-12 | Tesaro, Inc. | Metode liječenja raka jajnika |
| AU2018246214B2 (en) | 2017-03-27 | 2021-07-08 | Merck Sharp & Dohme Llc | Niraparib compositions |
| CN111278433A (zh) | 2017-09-26 | 2020-06-12 | 特沙诺有限公司 | 尼拉帕尼制剂 |
| CN109632555B (zh) * | 2018-12-28 | 2021-07-27 | 上海新黄河制药有限公司 | 一种富马酸福莫特罗无定型含量的动态蒸汽吸附分析方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7122679B2 (en) | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
| US20060276497A1 (en) | 2000-05-09 | 2006-12-07 | Cephalon, Inc. | Novel multicyclic compounds and the use thereof |
| CN101316592A (zh) * | 2005-08-24 | 2008-12-03 | 伊诺泰克制药公司 | 茚并异喹啉酮类似物及其用法 |
| WO2008063644A1 (en) | 2006-11-20 | 2008-05-29 | Cephalon, Inc. | Method of radio-sensitizing tumors using a radio-sensitizing agent |
| JP2013503173A (ja) * | 2009-08-26 | 2013-01-31 | セファロン、インク． | 多環系化合物の新規形態 |
-
2010
- 2010-08-25 JP JP2012526945A patent/JP2013503173A/ja active Pending
- 2010-08-25 CA CA2772328A patent/CA2772328C/en not_active Expired - Fee Related
- 2010-08-25 DK DK10750210.6T patent/DK2470540T3/en active
- 2010-08-25 EP EP10750210.6A patent/EP2470540B1/en active Active
- 2010-08-25 MY MYPI2012000710A patent/MY156873A/en unknown
- 2010-08-25 NZ NZ598883A patent/NZ598883A/en not_active IP Right Cessation
- 2010-08-25 WO PCT/US2010/046671 patent/WO2011028580A1/en not_active Ceased
- 2010-08-25 KR KR1020127007524A patent/KR20120092100A/ko not_active Ceased
- 2010-08-25 EA EA201270315A patent/EA020756B1/ru not_active IP Right Cessation
- 2010-08-25 CN CN2010800380284A patent/CN102482282A/zh active Pending
- 2010-08-25 SG SG2012012290A patent/SG178852A1/en unknown
- 2010-08-25 UA UAA201203501A patent/UA110604C2/uk unknown
- 2010-08-25 BR BR112012004053-7A patent/BR112012004053A2/pt not_active IP Right Cessation
- 2010-08-25 ES ES10750210.6T patent/ES2572652T3/es active Active
- 2010-08-25 AU AU2010289746A patent/AU2010289746B2/en not_active Ceased
- 2010-08-25 MX MX2012002456A patent/MX2012002456A/es active IP Right Grant
-
2012
- 2012-02-15 IL IL218132A patent/IL218132B/en not_active IP Right Cessation
- 2012-02-24 US US13/404,137 patent/US8633314B2/en not_active Expired - Fee Related
- 2012-02-24 CL CL2012000478A patent/CL2012000478A1/es unknown
-
2015
- 2015-07-30 JP JP2015151114A patent/JP2016014029A/ja not_active Ceased
-
2017
- 2017-09-04 JP JP2017169876A patent/JP2018035158A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CL2012000478A1 (es) | 2012-11-05 |
| EP2470540A1 (en) | 2012-07-04 |
| JP2018035158A (ja) | 2018-03-08 |
| MX2012002456A (es) | 2012-05-08 |
| CA2772328A1 (en) | 2011-03-10 |
| EA020756B1 (ru) | 2015-01-30 |
| EA201270315A1 (ru) | 2012-08-30 |
| AU2010289746B2 (en) | 2016-07-07 |
| JP2016014029A (ja) | 2016-01-28 |
| WO2011028580A1 (en) | 2011-03-10 |
| MY156873A (en) | 2016-04-15 |
| KR20120092100A (ko) | 2012-08-20 |
| NZ598883A (en) | 2014-09-26 |
| BR112012004053A2 (pt) | 2020-12-08 |
| EP2470540B1 (en) | 2016-04-20 |
| AU2010289746A1 (en) | 2012-04-12 |
| ES2572652T3 (es) | 2016-06-01 |
| HK1171750A1 (zh) | 2013-04-05 |
| CN102482282A (zh) | 2012-05-30 |
| US8633314B2 (en) | 2014-01-21 |
| UA110604C2 (uk) | 2016-01-25 |
| JP2013503173A (ja) | 2013-01-31 |
| SG178852A1 (en) | 2012-04-27 |
| DK2470540T3 (en) | 2016-08-01 |
| US20120214998A1 (en) | 2012-08-23 |
| IL218132A0 (en) | 2012-06-28 |
| IL218132B (en) | 2018-02-28 |
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Legal Events
| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20150327 |
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| MKLA | Lapsed |
Effective date: 20200831 |