EA020756B1 - Новые формы полициклического соединения - Google Patents

Новые формы полициклического соединения Download PDF

Info

Publication number
EA020756B1
EA020756B1 EA201270315A EA201270315A EA020756B1 EA 020756 B1 EA020756 B1 EA 020756B1 EA 201270315 A EA201270315 A EA 201270315A EA 201270315 A EA201270315 A EA 201270315A EA 020756 B1 EA020756 B1 EA 020756B1
Authority
EA
Eurasian Patent Office
Prior art keywords
compound
forms
mixture
χκρό
temperature
Prior art date
Application number
EA201270315A
Other languages
English (en)
Russian (ru)
Other versions
EA201270315A1 (ru
Inventor
Стефен Бирлмэйер
Майкл Кристи
Лоран Курвуазье
Р. Скотт Филд
Р. Кертис Холтиванджер
Линли Хи
Мартин Дж. Джейкобс
Майкл Кресс
Роберт Э. Маккин
Дейл Р. Маури
Джозеф Петрейтис
Мехран Язданиан
Original Assignee
Сефалон, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43033463&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA020756(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Сефалон, Инк. filed Critical Сефалон, Инк.
Publication of EA201270315A1 publication Critical patent/EA201270315A1/ru
Publication of EA020756B1 publication Critical patent/EA020756B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
EA201270315A 2009-08-26 2010-08-25 Новые формы полициклического соединения EA020756B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23718009P 2009-08-26 2009-08-26
PCT/US2010/046671 WO2011028580A1 (en) 2009-08-26 2010-08-25 Novel forms of a multicyclic compound

Publications (2)

Publication Number Publication Date
EA201270315A1 EA201270315A1 (ru) 2012-08-30
EA020756B1 true EA020756B1 (ru) 2015-01-30

Family

ID=43033463

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201270315A EA020756B1 (ru) 2009-08-26 2010-08-25 Новые формы полициклического соединения

Country Status (19)

Country Link
US (1) US8633314B2 (enExample)
EP (1) EP2470540B1 (enExample)
JP (3) JP2013503173A (enExample)
KR (1) KR20120092100A (enExample)
CN (1) CN102482282A (enExample)
AU (1) AU2010289746B2 (enExample)
BR (1) BR112012004053A2 (enExample)
CA (1) CA2772328C (enExample)
CL (1) CL2012000478A1 (enExample)
DK (1) DK2470540T3 (enExample)
EA (1) EA020756B1 (enExample)
ES (1) ES2572652T3 (enExample)
IL (1) IL218132B (enExample)
MX (1) MX2012002456A (enExample)
MY (1) MY156873A (enExample)
NZ (1) NZ598883A (enExample)
SG (1) SG178852A1 (enExample)
UA (1) UA110604C2 (enExample)
WO (1) WO2011028580A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013503173A (ja) * 2009-08-26 2013-01-31 セファロン、インク． 多環系化合物の新規形態
CA2967828A1 (en) 2014-11-26 2016-06-02 Cephalon, Inc. Crystalline forms of parp inhibitors
HRP20240136T1 (hr) 2016-06-29 2024-04-12 Tesaro, Inc. Metode liječenja raka jajnika
AU2018246214B2 (en) 2017-03-27 2021-07-08 Merck Sharp & Dohme Llc Niraparib compositions
CN111278433A (zh) 2017-09-26 2020-06-12 特沙诺有限公司 尼拉帕尼制剂
CN109632555B (zh) * 2018-12-28 2021-07-27 上海新黄河制药有限公司 一种富马酸福莫特罗无定型含量的动态蒸汽吸附分析方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008063644A1 (en) * 2006-11-20 2008-05-29 Cephalon, Inc. Method of radio-sensitizing tumors using a radio-sensitizing agent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122679B2 (en) 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
US20060276497A1 (en) 2000-05-09 2006-12-07 Cephalon, Inc. Novel multicyclic compounds and the use thereof
CN101316592A (zh) * 2005-08-24 2008-12-03 伊诺泰克制药公司 茚并异喹啉酮类似物及其用法
JP2013503173A (ja) * 2009-08-26 2013-01-31 セファロン、インク． 多環系化合物の新規形態

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008063644A1 (en) * 2006-11-20 2008-05-29 Cephalon, Inc. Method of radio-sensitizing tumors using a radio-sensitizing agent

Also Published As

Publication number Publication date
CL2012000478A1 (es) 2012-11-05
EP2470540A1 (en) 2012-07-04
JP2018035158A (ja) 2018-03-08
MX2012002456A (es) 2012-05-08
CA2772328A1 (en) 2011-03-10
EA201270315A1 (ru) 2012-08-30
AU2010289746B2 (en) 2016-07-07
JP2016014029A (ja) 2016-01-28
WO2011028580A1 (en) 2011-03-10
MY156873A (en) 2016-04-15
KR20120092100A (ko) 2012-08-20
NZ598883A (en) 2014-09-26
BR112012004053A2 (pt) 2020-12-08
EP2470540B1 (en) 2016-04-20
AU2010289746A1 (en) 2012-04-12
CA2772328C (en) 2017-06-20
ES2572652T3 (es) 2016-06-01
HK1171750A1 (zh) 2013-04-05
CN102482282A (zh) 2012-05-30
US8633314B2 (en) 2014-01-21
UA110604C2 (uk) 2016-01-25
JP2013503173A (ja) 2013-01-31
SG178852A1 (en) 2012-04-27
DK2470540T3 (en) 2016-08-01
US20120214998A1 (en) 2012-08-23
IL218132A0 (en) 2012-06-28
IL218132B (en) 2018-02-28

Similar Documents

Publication Publication Date Title
US11168057B2 (en) Polymorphs and co-crystals of roxadustat
CN103764637A (zh) 卡巴他赛的固态形式及其制备方法
IL310267A (en) Elagolix sodium compositions and processes
JP2018035158A (ja) 多環系化合物の新規形態
US20130158264A1 (en) Polymorphs of OSI-906
EA025561B1 (ru) Твёрдые формы производного хиназолина и их применение в качестве ингибитора braf
US20090131667A1 (en) Polymorphic forms of tadalafil
KR20250003750A (ko) [2-(1h-인돌-3-일)-1h-이미다졸-4-일](3,4,5-트리메톡시페닐)메타논 및 이의 염의 다형체
US20260070919A1 (en) Crystal form of five-membered and six-membered heterocyclic compound, preparation method therefor, and use thereof
JP2022525125A (ja) ブレイアコニチンａのｅ結晶形及びその製造方法と応用
CN114057643B (zh) 一种罗沙司他共晶及其制备方法
CN102725294B (zh) (s)-1-(4-(5-环丙基-1h-吡唑-3-基氨基)吡咯并[1,2-f][1,2,4]三嗪-2-基)-n-(6-氟吡啶-3-基)-2-甲基吡咯烷-2-甲酰胺的晶型
BRPI0711508A2 (pt) formas cristalinas a,b,c, e x , processo para preparar as formas cristalinas a,b,c,e x formulação farmacêutica, uso das formas a,b,c, e x, e processo para preparar a forma amorfa de cloridrato de (r) -5-(2-aminoetil) - 1 - (6,8 -difluorocroman -3- il), - 1,3-diidroimidazol - 2-tiona
RU2426735C2 (ru) Кристаллическая форма винфлунина дитартрата
WO2020249507A1 (en) Anhydrous crystalline form of cabazitaxel, a process for its preparation and pharmaceutical compositions containing it
AU2018201013B2 (en) Crystalline forms of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide mono hydrochloride
HK1171750B (en) Novel forms of a multicyclic compound
HK1254393A1 (zh) 1-(5-(2，4-二氟苯基)-1-((3-氟苯基)磺酰基)-4-甲氧基-1h-吡咯-3-基)-n-甲基甲胺盐新晶型
KR20170088894A (ko) Parp 억제제의 결정질 형태

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AZ BY KZ KG MD TJ TM RU