UA110604C2 - Кристалічна форма поліциклічної сполуки - Google Patents

Кристалічна форма поліциклічної сполуки Download PDF

Info

Publication number
UA110604C2
UA110604C2 UAA201203501A UAA201203501A UA110604C2 UA 110604 C2 UA110604 C2 UA 110604C2 UA A201203501 A UAA201203501 A UA A201203501A UA A201203501 A UAA201203501 A UA A201203501A UA 110604 C2 UA110604 C2 UA 110604C2
Authority
UA
Ukraine
Prior art keywords
shk
shi
compound
still
shchi
Prior art date
Application number
UAA201203501A
Other languages
English (en)
Ukrainian (uk)
Inventor
Стефен Бірлмейєр
Майкл Крісті
Лоран Курвуазьє
Р. Скотт Філд
Р. Кертіс Холтіванджер
Лінлі Хі
Мартін Дж. Джейкобс
Майкл Кресс
Роберт Е. Маккін
Дейл Р. Маурі
Джозеф Петрейтіс
Мехран Язданіан
Original Assignee
Сефалон, Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43033463&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA110604(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Сефалон, Інк. filed Critical Сефалон, Інк.
Publication of UA110604C2 publication Critical patent/UA110604C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
UAA201203501A 2009-08-26 2010-08-25 Кристалічна форма поліциклічної сполуки UA110604C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23718009P 2009-08-26 2009-08-26
PCT/US2010/046671 WO2011028580A1 (en) 2009-08-26 2010-08-25 Novel forms of a multicyclic compound

Publications (1)

Publication Number Publication Date
UA110604C2 true UA110604C2 (uk) 2016-01-25

Family

ID=43033463

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201203501A UA110604C2 (uk) 2009-08-26 2010-08-25 Кристалічна форма поліциклічної сполуки

Country Status (19)

Country Link
US (1) US8633314B2 (enExample)
EP (1) EP2470540B1 (enExample)
JP (3) JP2013503173A (enExample)
KR (1) KR20120092100A (enExample)
CN (1) CN102482282A (enExample)
AU (1) AU2010289746B2 (enExample)
BR (1) BR112012004053A2 (enExample)
CA (1) CA2772328C (enExample)
CL (1) CL2012000478A1 (enExample)
DK (1) DK2470540T3 (enExample)
EA (1) EA020756B1 (enExample)
ES (1) ES2572652T3 (enExample)
IL (1) IL218132B (enExample)
MX (1) MX2012002456A (enExample)
MY (1) MY156873A (enExample)
NZ (1) NZ598883A (enExample)
SG (1) SG178852A1 (enExample)
UA (1) UA110604C2 (enExample)
WO (1) WO2011028580A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2572652T3 (es) * 2009-08-26 2016-06-01 Cephalon, Inc. Nuevas formas de un compuesto multicíclico
CN107207511A (zh) * 2014-11-26 2017-09-26 赛福伦公司 Parp抑制剂的结晶形式
FI3478286T3 (fi) 2016-06-29 2024-03-14 Tesaro Inc Menetelmiä munasarjasyövän hoitamiseksi
EA201992177A1 (ru) * 2017-03-27 2020-02-25 Тесаро, Инк. Композиции на основе нирапариба
AU2018341479B2 (en) 2017-09-26 2022-02-17 Tesaro, Inc. Niraparib formulations
CN109632555B (zh) * 2018-12-28 2021-07-27 上海新黄河制药有限公司 一种富马酸福莫特罗无定型含量的动态蒸汽吸附分析方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060276497A1 (en) 2000-05-09 2006-12-07 Cephalon, Inc. Novel multicyclic compounds and the use thereof
US7122679B2 (en) * 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
RU2008110955A (ru) * 2005-08-24 2009-09-27 Инотек Фармасьютикалз Корпорейшн (Us) Инденоизохинолиноновые аналоги и способы их применения
DE602007009717D1 (de) 2006-11-20 2010-11-18 Cephalon Inc Verfahren zur strahlensensibilisierung von tumoren mit einem strahlensensibilisierungsmittel
ES2572652T3 (es) * 2009-08-26 2016-06-01 Cephalon, Inc. Nuevas formas de un compuesto multicíclico

Also Published As

Publication number Publication date
SG178852A1 (en) 2012-04-27
JP2016014029A (ja) 2016-01-28
ES2572652T3 (es) 2016-06-01
WO2011028580A1 (en) 2011-03-10
NZ598883A (en) 2014-09-26
JP2018035158A (ja) 2018-03-08
EA020756B1 (ru) 2015-01-30
AU2010289746A1 (en) 2012-04-12
MY156873A (en) 2016-04-15
AU2010289746B2 (en) 2016-07-07
JP2013503173A (ja) 2013-01-31
EA201270315A1 (ru) 2012-08-30
DK2470540T3 (en) 2016-08-01
CL2012000478A1 (es) 2012-11-05
CA2772328C (en) 2017-06-20
US8633314B2 (en) 2014-01-21
HK1171750A1 (zh) 2013-04-05
CN102482282A (zh) 2012-05-30
US20120214998A1 (en) 2012-08-23
EP2470540A1 (en) 2012-07-04
EP2470540B1 (en) 2016-04-20
MX2012002456A (es) 2012-05-08
CA2772328A1 (en) 2011-03-10
IL218132B (en) 2018-02-28
IL218132A0 (en) 2012-06-28
KR20120092100A (ko) 2012-08-20
BR112012004053A2 (pt) 2020-12-08

Similar Documents

Publication Publication Date Title
TWI915407B (zh) Ａｐｏｌ１抑制劑及其使用方法
US20230040262A1 (en) Stereoselective process for preparing substituted polycyclic pyridone derivatives
CA2871464C (en) Sulfonamide derivatives and their use in the inhibition of .alpha.4.beta.7 integrin-dependent process
ES2639052T3 (es) Forma polimórfica de hidrocloruro de pridopidina
EP3315499B1 (en) Crystal of (6S,9aS)-N-benzyl-8-({6-[3-(4-ethylpiperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-6-(2-fluoro-4-hydroxybenzyl)-4,7-dioxo-2-(prop-2-en-1-yl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide
CA2990521C (en) Pde9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases
US8921363B2 (en) Derivatives of 1 H-isoindol-3-amine, 1 H-iso-aza-indol-3amine, 3,4-dihydroisoquinolin-1-amine, and 1,4-dihydroisoquinolin-3-amine as beta-secretase inhibitors
ES2450568T3 (es) Compuestos espiero de amino-dihidrooxazina y amino-dihidrotiazina como moduladores de beta-secretasa y su uso médico
AU2019309706A1 (en) Elagolix sodium compositions and processes
BR112017019779B1 (pt) Composto, e, composição farmacêutica
TW200306176A (en) Chemical compounds
JP2018035158A (ja) 多環系化合物の新規形態
US20140031340A1 (en) 5-Amino-Oxazepine and 5-Amino-Thiazepane Compounds as Beta Secretase Antagonists and Methods of Use
CN104316608A (zh) 阿齐沙坦酯杂质的检测及其制备方法
CN116375707A (zh) Menin抑制剂及其用途
ES2784826T3 (es) Forma cristalina de un compuesto de 4H-pirazol[1,5-]benzimidazol, procedimiento de preparación de la misma e intermediario de la misma
ES2616752T3 (es) Composición y cocristal de aprepitant L-prolina
MX2014007009A (es) Formas solidas de clorhidrato de (1r,4r)-6´-fluoro-n,n-dimetil-4-f enil-4´,9´-dihidro-3´h-espiro-[ciclohexano-1,1´-pirano[3,4,b]indo l]-4-amina.
ES2926469T3 (es) Cristales de un derivado de benzoxazol
EA029975B1 (ru) ТВЕРДЫЕ ФОРМЫ (1r,4r)-6'-ФТОР-(N,N-ДИМЕТИЛ)-4-ФЕНИЛ-4'9'-ДИГИДРО-3'Н-СПИРО[ЦИКЛОГЕКСАН-1,1'-ПИРАНО[3,4,b]ИНДОЛ]-4-АМИНА И СЕРНОЙ КИСЛОТЫ
WO2014118180A1 (en) Crystalline form of linaclotide
RU2423992C1 (ru) Способ получения пакистанамина и берберина хлорида из berberis sibirica
KR102871840B1 (ko) 거대고리 화합물
CN118165008A (zh) 二苯并-1,3-氧氮杂环戊烷并异喹啉-1(2h)-酮类化合物及其制备方法和抗肿瘤应用
CN120774891A (zh) 用于抑制Nav1.8的钠通道调节剂