CA2769852A1 - Islet cell sheet, process for production thereof, and use thereof - Google Patents

Islet cell sheet, process for production thereof, and use thereof Download PDF

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Publication number
CA2769852A1
CA2769852A1 CA2769852A CA2769852A CA2769852A1 CA 2769852 A1 CA2769852 A1 CA 2769852A1 CA 2769852 A CA2769852 A CA 2769852A CA 2769852 A CA2769852 A CA 2769852A CA 2769852 A1 CA2769852 A1 CA 2769852A1
Authority
CA
Canada
Prior art keywords
islet
cell
islet cell
cell sheet
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2769852A
Other languages
English (en)
French (fr)
Inventor
Hirofumi Shimizu
Kazuo Ohashi
Rie Utoh
Kazuya Ise
Masayuki Yamato
Teruo Okano
Mitsukazu Gotoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tokyo Womens Medical University
Original Assignee
Tokyo Womens Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tokyo Womens Medical University filed Critical Tokyo Womens Medical University
Publication of CA2769852A1 publication Critical patent/CA2769852A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2539/00—Supports and/or coatings for cell culture characterised by properties
    • C12N2539/10—Coating allowing for selective detachment of cells, e.g. thermoreactive coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2769852A 2009-08-02 2010-08-02 Islet cell sheet, process for production thereof, and use thereof Abandoned CA2769852A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009-193648 2009-08-02
JP2009193648 2009-08-02
PCT/JP2010/063033 WO2011016423A1 (ja) 2009-08-02 2010-08-02 膵島細胞シート、製造方法及びその利用方法

Publications (1)

Publication Number Publication Date
CA2769852A1 true CA2769852A1 (en) 2011-02-10

Family

ID=43544318

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2769852A Abandoned CA2769852A1 (en) 2009-08-02 2010-08-02 Islet cell sheet, process for production thereof, and use thereof

Country Status (7)

Country Link
US (1) US20120210451A1 (enExample)
EP (1) EP2491957A4 (enExample)
JP (1) JP5717253B2 (enExample)
CN (1) CN102858380B (enExample)
CA (1) CA2769852A1 (enExample)
IN (1) IN2012DN01268A (enExample)
WO (1) WO2011016423A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004070023A1 (ja) * 2003-02-06 2004-08-19 Cellseed Inc. 前眼部関連細胞シート、３次元構造体、及びそれらの製造法
EP1600177B1 (en) * 2003-02-20 2016-05-25 Cellseed Inc. Endothelial cell sheet for cornea regeneration, method of producing the same and method of using the same
US9114192B2 (en) * 2004-04-25 2015-08-25 Cellseed Inc. Cultured periodontal ligament cell sheet, process for producing the same and method of use thereof
US20080131476A1 (en) 2005-02-28 2008-06-05 Masato Kanzaki Cultured Cell Sheet, Production Method and Tissue Repair Method Using Thereof
JP4921353B2 (ja) * 2005-02-28 2012-04-25 株式会社セルシード 培養細胞シート、製造方法及びその利用方法
EP2348099B1 (en) * 2008-10-14 2017-07-05 CellSeed Inc. Temperature-responsive cell culture substrate and method for producing the same
WO2012118099A1 (ja) * 2011-02-28 2012-09-07 学校法人 東京女子医科大学 サイトカイン産生細胞シートとその利用方法
JP2012205516A (ja) 2011-03-29 2012-10-25 Osaka Univ 人工皮膚モデルの製造方法、及び人工皮膚モデル
CA2833866C (en) * 2011-04-08 2019-05-21 Otsuka Pharmaceutical Factory, Inc. Method for producing sheet-like pancreatic islet
US10094816B2 (en) 2012-05-25 2018-10-09 Tokyo Women's Medical University Method of evaluating wetting characteristic of object
EP2894219B1 (en) * 2012-09-04 2018-03-28 Osaka University Artificial skin tissue, artificial skin model and manufacturing method therefor
BR112015031253B1 (pt) * 2013-06-13 2021-09-28 Orgenesis Ltd. Método para produção de uma população de células transdiferenciada
WO2015159889A1 (ja) * 2014-04-14 2015-10-22 学校法人福岡大学 インスリン産生細胞移植方法
MA41296A (fr) 2014-12-30 2017-11-07 Orgenesis Ltd Procédés de transdifférenciation et procédés d'utilisation de ceux-ci
JP2018518190A (ja) * 2015-06-25 2018-07-12 オークランド ユニサービシズ リミテッド 組織を培養する装置及び方法
EP3315596A4 (en) * 2015-06-26 2019-02-13 National Cerebral and Cardiovascular Center CELL CULTURE CONTAINER
KR101828696B1 (ko) * 2015-08-26 2018-02-12 울산대학교 산학협력단 인슐린분비세포 이식용 조성물 및 이의 제조방법
JP6593589B2 (ja) * 2015-09-30 2019-10-23 澁谷工業株式会社 細胞塊シートの作製方法および細胞塊シート
US20170304528A1 (en) * 2016-04-22 2017-10-26 DeepScience Ltd. Implantable medical device for delivering cells
WO2018207179A1 (en) 2017-05-08 2018-11-15 Orgenesis Ltd. Transdifferentiated cell populations and methods of use thereof
TWI875793B (zh) * 2019-08-08 2025-03-11 學校法人 東京女子醫科大學 創傷被覆用片及創傷被覆方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06104061B2 (ja) 1989-02-10 1994-12-21 花王株式会社 細胞培養支持体材料
JPH05168470A (ja) * 1990-08-08 1993-07-02 W R Grace & Co 複数の細胞種からなる細胞塊状体とシートおよびその製造法
EP0470681A3 (en) * 1990-08-08 1992-04-22 W.R. Grace & Co.-Conn. Cell clusters or sheets comprising a plurality of cell species and preparations thereof
JPH05192138A (ja) 1992-01-22 1993-08-03 Kao Corp 皮膚細胞培養法及び培養皮膚
WO1997028252A1 (en) * 1996-01-31 1997-08-07 Vivorx Pharmaceuticals, Inc. Process for aggregating cells and forming sheets of mammalian tissue in a horizontally rotating bioreactor
WO2000014542A2 (de) * 1998-09-08 2000-03-16 Privates Institut Bioserv Gmbh Diagnostisches verfahren zur erkennung einer pankreasfunktionsstörung
DK1264877T3 (da) * 2000-03-16 2013-10-28 Cellseed Inc Celledyrkningsbæremateriale, fremgangsmåde til samdyrkning af celler og samdyrket cellelag opnået derved
MXPA04005010A (es) * 2001-11-26 2005-04-08 Advanced Cell Tech Inc METODO PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS METODOS PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS HUMANOS REPROGRAMADOS Y CELULAS DEL TALLO HUMANAS AUTOLOGAS E ISOGENICAS.
EA200401244A1 (ru) * 2002-03-25 2005-02-24 Вашингтон Юниверсити Химерная поджелудочная железа
EP1600177B1 (en) * 2003-02-20 2016-05-25 Cellseed Inc. Endothelial cell sheet for cornea regeneration, method of producing the same and method of using the same
US20040176855A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
WO2004091679A1 (ja) * 2003-04-16 2004-10-28 Creative Co., Ltd. 細胞製剤
JP2006304791A (ja) 2005-03-31 2006-11-09 National Institute For Materials Science 三次元培養装置を用いた細胞集塊の大量形成法
ES2561944T3 (es) 2006-01-12 2016-03-01 Tokyo Women's Medical University Procedimiento para mantener la función de las células de tejido hepático durante un tiempo prolongado
KR100788800B1 (ko) * 2006-06-26 2007-12-27 이정익 자가 탄성연골로 캡슐화된 이식물 및 이의 제조방법
CN101147704A (zh) * 2006-09-18 2008-03-26 中国人民解放军军事医学科学院野战输血研究所 一种可移植的人工替代单元
US20100272697A1 (en) * 2007-04-10 2010-10-28 Ali Naji Pancreatic islet cells composition and methods
JP2008278769A (ja) 2007-05-08 2008-11-20 Hokkaido Univ 膵島細胞からなる３次元凝集体をインビトロで製造する方法

Also Published As

Publication number Publication date
WO2011016423A1 (ja) 2011-02-10
EP2491957A4 (en) 2013-10-02
JPWO2011016423A1 (ja) 2013-01-10
CN102858380A (zh) 2013-01-02
US20120210451A1 (en) 2012-08-16
JP5717253B2 (ja) 2015-05-13
IN2012DN01268A (enExample) 2015-05-15
CN102858380B (zh) 2016-03-23
EP2491957A1 (en) 2012-08-29

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150720

FZDE Dead

Effective date: 20190416